The Indispensable Role of Bacteria in Human Life and Environmental Health DOI Open Access

PD Gupta,

Dominika Skiba, Barbara Sawicka

et al.

Published: June 24, 2024

Background: Bacteria, among the earliest life forms on Earth, are integral to both human health and environmental ecosystems. They contribute essential processes such as digestion, nutrient absorption, immune defense, play key roles in biogeochemical cycles that sustain life. Objective: This paper explores indispensable role of bacteria health, emphasizing their contributions protection, ecosystem functioning. It also discusses advances understanding microbiome implications for therapeutic interventions. Methods: The study reviews existing literature microbiome, probiotics, cycling. analyses experimental evidence case studies, particularly focusing impact fecal microbiota transplantation (FMT) a tool. Metagenomic analysis techniques examined highlight diversity functionality gut bacteria. Results: Bacteria found be breaking down food, providing vital nutrients, protecting against pathogens. critical maintaining healthy system involved necessary health. reveals significant variations bacterial populations associated with disease, importance balanced microbiota. FMT shows promise an effective treatment various diseases, including gastrointestinal, metabolic, neurological disorders. Conclusions: crucial stability. Maintaining is overall well-being, interventions probiotics can offer benefits. Future research should focus further complex interactions between hosts develop targeted therapies conditions.

Language: Английский

From the Gut to the Brain: Is Microbiome a New Paradigm in Parkinson’s Disease Treatment? DOI Open Access
Cristiana Vilela, Bruna Araújo, Carla Guedes

et al.

Published: April 19, 2024

Parkinson's disease (PD) is recognized as the second most prevalent primary chronic neurodegenerative disorder of central nervous system. Clinically, PD characterized a movement disorder, exhibiting an incidence and mortality rate that increasing faster than any other neurological condition. In recent years, there has been growing interest concerning role gut microbiome in etiology pathophysiology PD. The establishment brain-gut axis now real, with evidence denoting bidirectional communication between brain microbiota through metabolic, immune, neuronal, endocrine mechanisms pathways. Among these, vagus nerve represents direct form gut. Given potential interactions bacteria drugs, it observed therapies for can have impact on composition microbiome. Therefore, scope present review, we will discuss current understanding whether this may be new paradigm treating devastating disease.

Language: Английский

Citations

2
The Indispensable Role of Bacteria in Human Life and Environmental Health DOI Open Access

PD Gupta,

Dominika Skiba, Barbara Sawicka

et al.

Published: June 24, 2024

Background: Bacteria, among the earliest life forms on Earth, are integral to both human health and environmental ecosystems. They contribute essential processes such as digestion, nutrient absorption, immune defense, play key roles in biogeochemical cycles that sustain life. Objective: This paper explores indispensable role of bacteria health, emphasizing their contributions protection, ecosystem functioning. It also discusses advances understanding microbiome implications for therapeutic interventions. Methods: The study reviews existing literature microbiome, probiotics, cycling. analyses experimental evidence case studies, particularly focusing impact fecal microbiota transplantation (FMT) a tool. Metagenomic analysis techniques examined highlight diversity functionality gut bacteria. Results: Bacteria found be breaking down food, providing vital nutrients, protecting against pathogens. critical maintaining healthy system involved necessary health. reveals significant variations bacterial populations associated with disease, importance balanced microbiota. FMT shows promise an effective treatment various diseases, including gastrointestinal, metabolic, neurological disorders. Conclusions: crucial stability. Maintaining is overall well-being, interventions probiotics can offer benefits. Future research should focus further complex interactions between hosts develop targeted therapies conditions.

Language: Английский

Citations

1