Comparative Study of Condensed and Hydrolysable Tannins during Early Stages of Zebrafish Development DOI Open Access
Alessandra La Pietra, Roberta Imperatore, Elena Coccia

et al.

Published: April 28, 2024

In this study, we present data on the effects of condensed (CTs) and hydrolysable (HTs) tannins, polyphenols extracted from plants, at different concentrations zebrafish development to identify range with toxic effects. Zebrafish embryos were exposed CTs HTs two concentration ranges (5.0, 10.0, 20.0 μgL-1 5.0, mgL-1) for 72 h. The toxicity parameters observed up h treatment. uptake by larvae was assessed HPLC analysis. qRT-PCR analysis performed evaluate gene expression cd63, zhe1 klf4, involved in hatching process zebrafish. not toxic. On contrary, mgL-1 induced a delayed starting 48 treatment, while showed mainly 48h. down-regulation group confirming data. We believe that study is important define optimal doses HTs, be employed application fields such as chemical animal feed industry, medical science.

Language: Английский

Comparative Study of Condensed and Hydrolysable Tannins during Early Stages of Zebrafish Development DOI Open Access
Alessandra La Pietra, Roberta Imperatore, Elena Coccia

et al.

Published: April 28, 2024

In this study, we present data on the effects of condensed (CTs) and hydrolysable (HTs) tannins, polyphenols extracted from plants, at different concentrations zebrafish development to identify range with toxic effects. Zebrafish embryos were exposed CTs HTs two concentration ranges (5.0, 10.0, 20.0 μgL-1 5.0, mgL-1) for 72 h. The toxicity parameters observed up h treatment. uptake by larvae was assessed HPLC analysis. qRT-PCR analysis performed evaluate gene expression cd63, zhe1 klf4, involved in hatching process zebrafish. not toxic. On contrary, mgL-1 induced a delayed starting 48 treatment, while showed mainly 48h. down-regulation group confirming data. We believe that study is important define optimal doses HTs, be employed application fields such as chemical animal feed industry, medical science.

Language: Английский

Citations

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