Published: April 29, 2024
Many ailments can be diagnosed while they are asymptomatic, meaning that the patient has no signs or symptoms of a progressing disease. If caught in their initial stage formation, these maladies effectively treated, leading to successful outcomes; curative therapies halt illnesses from advancing, thus improving quality life, and long-term survival patient. Still cutting-edge upgrades precision technologies necessary for early, reliable, affordable, rapid disease detection, but also vital well-being people future global public health. The emerging role utility non-invasive repeatable diagnostic test approaches detection health conditions been liquid biopsies based on genomic biomarkers. As such, biological fluids permit any measurable molecular indicator signature (e.g., proteins), provide valuable information individual’s wellness and/or Among bodily secretions used diagnostics is sputum, complex viscous gel-like biopolymeric network, gained growing recognition as rich source biomarkers airway infections, pulmonary diseases, serves determinant reveal other illnesses. per World Health Organization, burden respiratory exacerbated by factors, ranging considerable subjection air pollution occupational contaminants, tobacco smoking second-hand smoke, addition poor socio-economic status. Due likely increase determinants, tract rise, affecting many individuals, putting stress healthcare facilities services worldwide. We therefore highlight need use expectorated induced sputum specimens routine sample testing protein diagnose chronic maladies, predict inflammation progression, well monitor effectiveness treatments. Further, we discuss urgency fast reliable point-of-care methods detect quantify crucial specimens, limitations faced when dealing with matrices.
Language: Английский