Effects of Gestational Intermittent Hypoxia on the Respiratory System: A Tale of the Placenta, Fetus and Developing Offspring DOI Open Access
Esther Valverde‐Pérez, Elena Olea, Asunción Rocher

et al.

Published: May 2, 2024

Obstructive sleep apnea (OSA) is a common disorder that associated with wide variety of health conditions, including cardiovascular, cerebrovascular, metabolic, neoplastic, and neurocognitive manifestations. OSA mainly characterized by repeated upper airway obstructions during cause episodes chronic intermittent hypoxia (IH), resulting in tissue hypoxia-reoxygenation. Decreased arterial oxygen pressure (PaO2) hemoglobin saturation (SatO2) stimulate reflex responses to overcome the obstruction. The prevalence significant worldwide, particularly women pregnancy, due physiological changes this stage life, especially its later stages. It an increased risk hypertension, pre-eclampsia diabetes, among others. pregnancy can interfere normal fetal development growth retardation, preterm birth, or low term weight. Carotid body stimulation hypoxia-reoxygenation contribute cardiovascular disease oxidative stress, harm both, mother fetus, even into adulthood. Because gestational (GIH) hallmark review examines impact GIH on maternal, fetal, offspring respiratory outcomes. Most adverse outcomes be prevented continuous positive (CPAP) therapy lifestyle if detected early treated appropriately.

Language: Английский

Effects of Gestational Intermittent Hypoxia on the Respiratory System: A Tale of the Placenta, Fetus and Developing Offspring DOI Open Access
Esther Valverde‐Pérez, Elena Olea, Asunción Rocher

et al.

Published: May 2, 2024

Obstructive sleep apnea (OSA) is a common disorder that associated with wide variety of health conditions, including cardiovascular, cerebrovascular, metabolic, neoplastic, and neurocognitive manifestations. OSA mainly characterized by repeated upper airway obstructions during cause episodes chronic intermittent hypoxia (IH), resulting in tissue hypoxia-reoxygenation. Decreased arterial oxygen pressure (PaO2) hemoglobin saturation (SatO2) stimulate reflex responses to overcome the obstruction. The prevalence significant worldwide, particularly women pregnancy, due physiological changes this stage life, especially its later stages. It an increased risk hypertension, pre-eclampsia diabetes, among others. pregnancy can interfere normal fetal development growth retardation, preterm birth, or low term weight. Carotid body stimulation hypoxia-reoxygenation contribute cardiovascular disease oxidative stress, harm both, mother fetus, even into adulthood. Because gestational (GIH) hallmark review examines impact GIH on maternal, fetal, offspring respiratory outcomes. Most adverse outcomes be prevented continuous positive (CPAP) therapy lifestyle if detected early treated appropriately.

Language: Английский

Citations

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