Virulence Molecular Epidemiology of Clinical Carbapenem-Resistant Acinetobacter baumannii: First Report from Jordan DOI Open Access
AbdelRahman Zueter,

Dua’a Al Balawi,

Mohammad Al‐Tamimi

et al.

Published: May 7, 2024

1) Background: carbapenem-resistant Acinetobacter baumannii (CRAB) is an opportunistic Gram-negative pathogen that has a significant role in healthcare-associated infections. Unlike several studies on the antibiotic-resistant epidemiology of A. baumanni, virulence molecular was less studied. This study aimed to investigate CRAB genes and their ability form biofilms, correlate biofilm formation with both; biofilm-encoding carbapenemase-encoding resistance genes. 2) Methods: 107 clinical isolates were collected from two hospitals Jordan between 2018 2019 screened for using PCR. In addition, assessed microtiter plate method. 3) Results: frequencies bap, OmpA, surA, PLD, paaE, basD, traT 99.10%, 98.20%, 95.50%, 89.10%, 86.40%, 8.20%, respectively. Overall, 86.4% tested formers varying degrees; weak (28.2%), moderate (36.4%) strong (21.8%). A relationship found gene (OXA-23 gene) production. 4) Conclusion: best our knowledge, this first inspected highlighted importance improving infection control measures avoid outbreaks.

Language: Английский

Virulence Molecular Epidemiology of Clinical Carbapenem-Resistant Acinetobacter baumannii: First Report from Jordan DOI Open Access
AbdelRahman Zueter,

Dua’a Al Balawi,

Mohammad Al‐Tamimi

et al.

Published: May 7, 2024

1) Background: carbapenem-resistant Acinetobacter baumannii (CRAB) is an opportunistic Gram-negative pathogen that has a significant role in healthcare-associated infections. Unlike several studies on the antibiotic-resistant epidemiology of A. baumanni, virulence molecular was less studied. This study aimed to investigate CRAB genes and their ability form biofilms, correlate biofilm formation with both; biofilm-encoding carbapenemase-encoding resistance genes. 2) Methods: 107 clinical isolates were collected from two hospitals Jordan between 2018 2019 screened for using PCR. In addition, assessed microtiter plate method. 3) Results: frequencies bap, OmpA, surA, PLD, paaE, basD, traT 99.10%, 98.20%, 95.50%, 89.10%, 86.40%, 8.20%, respectively. Overall, 86.4% tested formers varying degrees; weak (28.2%), moderate (36.4%) strong (21.8%). A relationship found gene (OXA-23 gene) production. 4) Conclusion: best our knowledge, this first inspected highlighted importance improving infection control measures avoid outbreaks.

Language: Английский

Citations

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