
Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(10), P. 1325 - 1325
Published: Oct. 12, 2024
Eye disorders affect a substantial portion of the global population, yet availability efficacious ophthalmic drug products remains limited. This can be partly ascribed to number factors: (1) inadequate understanding physiological barriers, treatment strategies, and polymer properties, delivery systems; (2) challenges in effectively delivering drugs anterior posterior segments eye due anatomical constraints; (3) manufacturing regulatory hurdles ocular product development. The present review discusses innovative treatments, encompassing implants, liposomes, nanoparticles, nanomicelles, microparticles, iontophoresis, situ gels, contact lenses, microneedles, hydrogels, bispecific antibodies, gene strategies. Furthermore, this also introduces advanced technologies such as 3D printing hot-melt extrusion (HME), aimed at improving bioavailability, reducing therapeutic dosages side effects, facilitating design personalized dosage forms, well enhancing patient compliance. comprehensive lastly offers insights into digital healthcare, market trends, industry perspectives pertaining
Language: Английский