Drinking Water Microbiota, Entero-Mammary Pathways and Breast Cancer: Focus on Nontuberculous Mycobacteria DOI Open Access
Ana Maranha, Susana Alarico, Daniela Nunes‐Costa

et al.

Published: June 20, 2024

The prospect of drinking water serving as a conduit for gut bacteria, artificially selected by disinfection strategies and lack monitoring at the point use, is concerning. Certain opportunistic pathogens, notably some nontuberculous mycobacteria (NTM), often exceed coliform bacteria levels in water, posing safety risks. NTM other microbiota resist chlorination thrive plumbing systems. When inhaled, can infect lungs immunocompromised or chronically ill patients, elderly, primarily postmenopausal women. ingested with survive stomach acidity, reach intestines, migrate to organs using immune cells vehicles, potentially colonizing tumor tissue, including breast cancer. link between microbiome cancer not new, yet recognition intratumoral microbiomes recent development. Breast risk rises age, infections emerged concern among patients. In addition studies hinting potential association chronic lung cancer, have also been detected tumors higher than normal adjacent tissue. Evaluating risks continued ingestion contaminated paramount, especially given ability various from tissue via entero-mammary pathways. This underscores pressing need revise guidelines delve into hormonal factors, which includes addressing disproportionate impact on women examining health posed cryptic unchecked water.

Language: Английский

Drinking Water Microbiota, Entero-Mammary Pathways and Breast Cancer: Focus on Nontuberculous Mycobacteria DOI Open Access
Ana Maranha, Susana Alarico, Daniela Nunes‐Costa

et al.

Published: June 20, 2024

The prospect of drinking water serving as a conduit for gut bacteria, artificially selected by disinfection strategies and lack monitoring at the point use, is concerning. Certain opportunistic pathogens, notably some nontuberculous mycobacteria (NTM), often exceed coliform bacteria levels in water, posing safety risks. NTM other microbiota resist chlorination thrive plumbing systems. When inhaled, can infect lungs immunocompromised or chronically ill patients, elderly, primarily postmenopausal women. ingested with survive stomach acidity, reach intestines, migrate to organs using immune cells vehicles, potentially colonizing tumor tissue, including breast cancer. link between microbiome cancer not new, yet recognition intratumoral microbiomes recent development. Breast risk rises age, infections emerged concern among patients. In addition studies hinting potential association chronic lung cancer, have also been detected tumors higher than normal adjacent tissue. Evaluating risks continued ingestion contaminated paramount, especially given ability various from tissue via entero-mammary pathways. This underscores pressing need revise guidelines delve into hormonal factors, which includes addressing disproportionate impact on women examining health posed cryptic unchecked water.

Language: Английский

Citations

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