The Past, Present and Future of Plant Activator Targeting Salicylic Acid Signal Pathway

Published: July 17, 2024

Plant activators have emerged as promising alternatives to conventional pesticides for crop disease manage-ment due their unique mode of action. By priming the plant's innate immune system, these compounds can induce systemic acquired resistance against a broad spectrum pathogens without directly inhibiting proliferation. Key advantages plant include prolonged defense activity, lower effective dosages, and negligible risk developing pathogen resistance. Among various defensive pathways tar-geted, salicylic acid (SA) signaling cascade has been extensively explored, leading successful devel-opment commercial like benzothiadiazole widespread application in protection. While action sites many SA-targeting preliminarily mapped different steps along pathway, comprehensive understanding precise mechanisms remains elusive. This review provides historical perspective on activator development outlines diverse screening strategies employed across multiple levels, from whole-plant bioassays molecular transgenic approaches. We expound intricate components, biological relevance, regulatory circuits governing SA while criti-cally examining structural features, bioactivities, proposed modes classical such derivatives, analogs, other small molecules. Insights field trials as-sessing practical applicability are also discussed. Furthermore, we highlight current status, challenges, future prospects realm globally, with focus recent en-deavors China. Collectively, this aims synthesize existing knowledge provide roadmap research toward more potent mechanistically understood activa-tors that fortify immunity disease.

Language: Английский

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Plant Secondary Metabolites—Central Regulators Against Abiotic and Biotic Stresses

Metabolites, Journal Year: 2025, Volume and Issue: 15(4), P. 276 - 276

Published: April 16, 2025

As global climates shift, plants are increasingly exposed to biotic and abiotic stresses that adversely affect their growth development, ultimately reducing agricultural productivity. To counter these stresses, produce secondary metabolites (SMs), which critical biochemical essential compounds serve as primary defense mechanisms. These diverse compounds, such alkaloids, flavonoids, phenolic nitrogen/sulfur-containing act natural protectants against herbivores, pathogens, oxidative stress. Despite the well-documented protective roles of SMs, precise mechanisms by environmental factors modulate accumulation under different stress conditions not fully understood. This review provides comprehensive insights into recent advances in understanding functions SMs plant emphasizing regulatory networks biosynthetic pathways. Furthermore, we explored unique contributions individual SM classes responses while integrating findings across entire spectrum diversity, providing a resilience multiple conditions. Finally, highlight emerging strategies for harnessing improve crop through genetic engineering present novel solutions enhance sustainability changing climate.

Language: Английский

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Enhanced Antifungal Efficacy of Validamycin A Co-Administered with Bacillus velezensis TCS001 against Camellia anthracnose

Plants, Journal Year: 2024, Volume and Issue: 13(19), P. 2743 - 2743

Published: Sept. 30, 2024

Anthracnose, a fungal disease harming fruit trees and crops, poses threat to agriculture. Traditional chemical pesticides face issues like environmental pollution resistance. A strategy combining low-toxicity chemicals with biopesticides is proposed enhance control while reducing use. Our study found that mixing validamycin (VMA)

Language: Английский

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Chemical and Biological Investigations of Antiviral Agents Against Plant Viruses Conducted in China in the 21st Century

Genes, Journal Year: 2024, Volume and Issue: 15(12), P. 1654 - 1654

Published: Dec. 23, 2024

Research into the biology of plant viruses, their mechanisms pathogenicity, and induction host resistance has laid a solid foundation for discovery antiviral agents targets development effective control technologies. Additionally, recent advancements in fields such as chemical biology, cheminformatics, bioinformatics, synthetic have provided valuable methods tools design drugs, synthesis drug molecules, assessment activity, investigation modes action. Compared with human viral diseases, diseases presents greater challenges, including cost-benefit agents, simplification technologies, effectiveness treatments. Therefore, current context complex outbreaks severe damage caused by it is crucial to delve deeper research agents. This review provides detailed overview biological characteristics mode interaction between virus antivirals, insights future development. We believe this will not only facilitate in-depth analysis antivirals crops but also offer perspectives use veterinary medicine.

Language: Английский

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