Gut Microbiota in Regulating Natural Bioactive Polysaccharides on Metabolic Diseases: A Review DOI Open Access
Yu Pi,

Miaoyu Fang,

Yanpin Li

et al.

Published: July 18, 2024

The gut microbiota constitutes a complex ecosystem, comprising trillions of microbes that have co-evolved with their host over hundreds millions years. Over the past decade, growing body knowledge has underscored intricate connections among diet, microbiota, and human health. Bioactive polysaccharides (BPs) from natural sources like medicinal plants, sea-weeds, fungi diverse biological functions, including antioxidant, immunoregulatory, metabolic activities. Their effects are closely tied to which metabolizes BPs into health-influencing compounds. Understanding how interact is critical for harnessing potential health benefits. This review provides an overview focusing on its role in diseases obesity, type II diabetes mellitus (T2DM), non-alcoholic fatty liver disease (NAFLD), cardiovascular (CVD). It explores basic characteristics several impact microbiota. Given significance health, we summarize functions these BPs, particularly terms im-munoregulatory activities, blood sugar, hypolipidemic effect, providing valuable reference understanding benefits treating diseases. These properties make promising agents preventing comprehensive mechanisms by exert through opens new avenues developing targeted therapies improve

Language: Английский

Gut Microbiota in Regulating Natural Bioactive Polysaccharides on Metabolic Diseases: A Review DOI Open Access
Yu Pi,

Miaoyu Fang,

Yanpin Li

et al.

Published: July 18, 2024

The gut microbiota constitutes a complex ecosystem, comprising trillions of microbes that have co-evolved with their host over hundreds millions years. Over the past decade, growing body knowledge has underscored intricate connections among diet, microbiota, and human health. Bioactive polysaccharides (BPs) from natural sources like medicinal plants, sea-weeds, fungi diverse biological functions, including antioxidant, immunoregulatory, metabolic activities. Their effects are closely tied to which metabolizes BPs into health-influencing compounds. Understanding how interact is critical for harnessing potential health benefits. This review provides an overview focusing on its role in diseases obesity, type II diabetes mellitus (T2DM), non-alcoholic fatty liver disease (NAFLD), cardiovascular (CVD). It explores basic characteristics several impact microbiota. Given significance health, we summarize functions these BPs, particularly terms im-munoregulatory activities, blood sugar, hypolipidemic effect, providing valuable reference understanding benefits treating diseases. These properties make promising agents preventing comprehensive mechanisms by exert through opens new avenues developing targeted therapies improve

Language: Английский

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