Next-Generation Pharmaceuticals: The Rise of Orodispersible Formulation Technology for Male Sexual Health DOI Open Access
Emmanuele A. Jannini,

Shivani Ohri Vignesh,

Tarek A. Hassan

et al.

Published: July 29, 2024

Abstract: Orodispersible film (ODF) is one of the novel formulations that have been currently made available disintegrates rapidly in mouth without requisite for water and offer several benefits over conventional oral solid dosage formulations. This delivery system serves as a discreet convenient mode administration, especially patients who dysphagia, fluid restriction, being beneficial to pediatric, geriatric, bedridden patients. A sildenafil ODF containing citrate formulated be used with erectile dysfunction (ED). review discusses advantages improving compliance satisfaction these describes bioequivalence stability studies ODF. formulation offers unique benefit ED by their acceptance, compliance, respecting privacy. Moreover, comparison pharmacokinetic parameters between administered film-coated tablet were similar. It also demonstrated reliable performance yielded consistent product, meeting all specifications at release after three weeks storage under stressed conditions (60oC). Sildenafil warrants improved ease intake, taste, portability, storage, among patients, making it potential most preferred drug choice.

Language: Английский

Next-Generation Pharmaceuticals: The Rise of Orodispersible Formulation Technology for Male Sexual Health DOI Open Access
Emmanuele A. Jannini,

Shivani Ohri Vignesh,

Tarek A. Hassan

et al.

Published: July 29, 2024

Abstract: Orodispersible film (ODF) is one of the novel formulations that have been currently made available disintegrates rapidly in mouth without requisite for water and offer several benefits over conventional oral solid dosage formulations. This delivery system serves as a discreet convenient mode administration, especially patients who dysphagia, fluid restriction, being beneficial to pediatric, geriatric, bedridden patients. A sildenafil ODF containing citrate formulated be used with erectile dysfunction (ED). review discusses advantages improving compliance satisfaction these describes bioequivalence stability studies ODF. formulation offers unique benefit ED by their acceptance, compliance, respecting privacy. Moreover, comparison pharmacokinetic parameters between administered film-coated tablet were similar. It also demonstrated reliable performance yielded consistent product, meeting all specifications at release after three weeks storage under stressed conditions (60oC). Sildenafil warrants improved ease intake, taste, portability, storage, among patients, making it potential most preferred drug choice.

Language: Английский

Citations

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