Investigation of relationship between lumbar Modic changes and serum vitamin D concentrations DOI Creative Commons
Server İlter, Veysel Delen, Murat Toprak

et al.

Van Medical Journal, Journal Year: 2024, Volume and Issue: 31(2), P. 142 - 146

Published: Jan. 1, 2024

Introduction:There is limited and inconsistent data on the relationship between vitamin D deficiency Modic changes (MCs).Also, which type of MCs associated with not clear.Vitamin has anti-inflammatory effects, while 1 inflammatory nature.Accordingly, patients may have lower levels than those 2 MCs.This study aimed to com pare for serum concentrations. Materials Methods:Between May 2019 July 2020, a total 53 or were included in this study.Patients' demographics recorded, back pain severity was assessed by using visual analog scale.Serum measured as 25-hydroxy D. Accordingly, (µg/L) are graded deficient (<20), insufficient (20 -30), sufficient (30-80).Results: Type (n=26) (n=27) groups similar age (p=0.199),gender, BMI, work status, duration, concentration, degree (p=0.773), spinal levels.Type had more painful low patients. Conclusion:Type concentration.The be related its nature, but insufficiency.

Language: Английский

"Vitamin D and its Antioxidant and Anti-Inflammatory Role in Cardiovascular Diseases" DOI Open Access
Kali Makedou

Biomedical Journal of Scientific & Technical Research, Journal Year: 2023, Volume and Issue: 50(1)

Published: April 26, 2023

Vitamin D an hormone synthesized in the skin by ultraviolet radiation, regulating bone metabolism, but has many extra-skeletal actions as well. It been suggested that vitamin plays a significant role pathophysiology of cardiovascular diseases. Its involvement anti-inflammatory and antioxidant mechanisms results inverse relationship between levels cardiometabolic risk, shown observational studies. Randomized controlled studies have supplementation decreased inflammatory oxidative stress biomarkers.

Language: Английский

Citations

1
"Prevalence of Vitamin D Deficiency and Relation to Chronic Diseases" DOI Open Access
Kali Makedou

Biomedical Journal of Scientific & Technical Research, Journal Year: 2023, Volume and Issue: 51(1)

Published: June 21, 2023

Vitamin D is a hormone produced in the skin by ultraviolet radiation and plays crucial role calcium homeostasis. It has been lately acknowledged that vitamin participates pathophysiology of various chronic diseases its deficiency linked to deterioration patients’ condition. The aim this study was record levels 25(OH)D population rural, near-border area Northern Greece investigate possible association an underline disease. These are preliminary results on epidemiology genetic polymorphisms receptor transfer protein.

Language: Английский

Citations

1
Research Progress on the Application of Deshumazumab in Osteoporosis DOI

宁 马

Advances in Clinical Medicine, Journal Year: 2023, Volume and Issue: 13(08), P. 13454 - 13463

Published: Jan. 1, 2023

Language: Английский

Citations

1
Complex Interplay of Psychiatry Disorders, Fractures, and Osteoporosis: A Mendelian Randomization Study DOI Creative Commons

xueqiang wu,

zefang Li,

Han‐Zheng Li

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: Oct. 24, 2023

Abstract Background Neurodevelopmental disorders, such as Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum (ASD), and Tourette Syndrome (TS), have been extensively studied for their multifaceted impacts on psychological, social, emotional well-being. Recently, there has growing interest in potential relationship with fracture risks adulthood. This study aims to explore the associations between these disorders rates, considering factors like self-harm impact of psychotropic medications. Methods Employing a novel approach, this utilized Mendelian randomization (MR) analysis investigate complex interplay ADHD, ASD, TS, fractures. The MR framework, leveraging extensive genomic datasets, facilitated systematic examination causal relationships genetic predispositions. Results findings unveil intriguing bidirectional links specific types Notably, ADHD is identified risk factor fractures, pronounced various anatomical regions, including skull, trunk, lower limbs. Conversely, individuals notably those affecting femur lumbar spine, exhibit an increased predisposition ASD. These results provide perspective neurodevelopmental emphasizing importance early diagnosis, intervention, holistic approach healthcare. Conclusion research sheds new light intricate connections offering valuable insights into links. fractures highlight need comprehensive clinical approaches that consider both psychological physical Early pharmacological interventions, diligent monitoring bone health are essential components improved healthcare strategies

Language: Английский

Citations

1
Investigation of relationship between lumbar Modic changes and serum vitamin D concentrations DOI Creative Commons
Server İlter, Veysel Delen, Murat Toprak

et al.

Van Medical Journal, Journal Year: 2024, Volume and Issue: 31(2), P. 142 - 146

Published: Jan. 1, 2024

Introduction:There is limited and inconsistent data on the relationship between vitamin D deficiency Modic changes (MCs).Also, which type of MCs associated with not clear.Vitamin has anti-inflammatory effects, while 1 inflammatory nature.Accordingly, patients may have lower levels than those 2 MCs.This study aimed to com pare for serum concentrations. Materials Methods:Between May 2019 July 2020, a total 53 or were included in this study.Patients' demographics recorded, back pain severity was assessed by using visual analog scale.Serum measured as 25-hydroxy D. Accordingly, (µg/L) are graded deficient (<20), insufficient (20 -30), sufficient (30-80).Results: Type (n=26) (n=27) groups similar age (p=0.199),gender, BMI, work status, duration, concentration, degree (p=0.773), spinal levels.Type had more painful low patients. Conclusion:Type concentration.The be related its nature, but insufficiency.

Language: Английский

Citations

0