The Procalcitonin Combined with C-Reactive Protein/Albumin Ratio as a Predictor of Mortality in Patients After Lung Transplantation DOI Creative Commons
Chenhao Xuan, Dapeng Wang, Song Wang

et al.

Intensive Care Research, Journal Year: 2023, Volume and Issue: 3(3), P. 221 - 228

Published: July 26, 2023

Abstract Background The Procalcitonin (PCT) and C-reactive protein (CRP)/albumin ratio have recently been used to predict early prognosis for intensive care unit (ICU) patients undergoing major surgery. But there were few clinical studies in after lung transplantation (LTX). Aim/Purpose purpose of this study was identify the association between PCT combined with CRP/albumin 30-day mortality accuracy LTX. Method From January 1, 2016 December 2020, data 77 LTX who died within 30 days retrospectively collected, we randomly collected 87 survived more than ROC curve evaluate prognostic value predicting at ICU admission, Cox proportional hazard model analysis risk factors, subgroup analyses conducted. Results Postoperative PCT, CRP, albumin, ratio, atrial fibrillation, primary graft dysfunction (PGD) grade, hours postoperative mechanical ventilation (MV) length stay survivor non-survivor had a significant difference . On regression analysis, both [HR 1.02 (1.00–1.05), P = 0.037] 1.438 (1.26–1.65), < 0.001] independent predictors mortality. In all LTX, area under (AUC) 0.76 (95% CI 0.69–0.83). AUC 0.83 0.75–0.91) interstitial pulmonary fibrosis (IPF). Conclusion could be predictor outcomes predictive efficacy better IPF.

Language: Английский

Assessing the Quality of Life in Adult Lung Transplant Recipients Quality of Life Post‐Lung Transplant DOI Open Access

Bashayer M. Al‐Shweeman,

Gamal A. Mohamed,

Atheer Alawwad

et al.

Clinical Transplantation, Journal Year: 2025, Volume and Issue: 39(2)

Published: Jan. 30, 2025

ABSTRACT Background Significant limitations in daily life characterize end‐stage lung diseases (ESLD) due to symptoms such as dyspnea, recurrent infections, side effects of immunosuppressive medication, and frequent need for hospitalizations. In addition physical symptoms, ESLD is associated with emotional social sources distress depression, anxiety, fear dying, financial concerns, regular relocation. A transplant can significantly affect the recipients’ domains, from well‐being relationships roles. Objective This study aims assess quality adult recipients Saudi Arabia. Method cross‐sectional quantitative design was employed using self‐administered World Health Organization Quality Life (WHOQOL‐BREF) questionnaire, a sociodemographic clinical medical chart review. The conducted tertiary care center Data were collected November 2023 April 2024. Results One hundred fifty‐seven individuals mean age 45 years had completed there no participant refusal (Response rate = 100%). Males accounted 61.1%, most participants married (63.7%). About half (44.6%) at least one comorbidity outside ESLD. Only 26.7% working post‐transplant. Overall, data strongly suggests that adjust recover post‐transplant, they tend feel increasingly positive time. Most rated their health satisfaction high. lowest score domain . Conclusion study's findings showed good overall across various moderate scores, on Improving rehabilitation strategies would help transplanted patients live more fulfilling lives.

Language: Английский

Citations

0
Nutrition support management of organ transplant recipients in the acute posttransplant phase DOI
Michaelann Hahn,

Abby Wood,

Jeanette M. Hasse

et al.

Nutrition in Clinical Practice, Journal Year: 2023, Volume and Issue: 39(1), P. 45 - 58

Published: Dec. 11, 2023

Abstract Patients who undergo solid organ transplant can have an extensive and challenging postoperative course. The chronicity of the disease state prior to in combination with transplant‐specific complications immunosuppressant medications lead distinct challenges that are not observed other critically ill patients. Although manifestation posttransplant may be specific being transplanted, there common affect nutrition therapy these Effects malnutrition, metabolic aberrations, dysfunction should considered when developing a care plan for patients immediate phase. This article addresses various arise phase among undergoing appropriate interventions or considerations this specialized patient population.

Language: Английский

Citations

4
Assessing nutrition status, sarcopenia, and frailty in adult transplant recipients DOI
Astrid Ruiz‐Margáin, Ricardo Ulises Macías‐Rodríguez,

Nayelli C Flores-García

et al.

Nutrition in Clinical Practice, Journal Year: 2023, Volume and Issue: 39(1), P. 14 - 26

Published: Dec. 14, 2023

The assessment of nutrition status, sarcopenia, and frailty holds significant relevance in the context adult transplantation, as these factors are associated with an unfavorable prognosis; thus, transplant candidates must undergo a full assessment. Screening tools may be used to prioritize patients, this can done using Nutrition Risk 2002 or Royal Free Hospital-Nutritional Prioritizing Tool. Subsequently, thorough nutrition-focused physical examination should conducted evaluate clinical signs deficiencies, fat muscle loss, fluid overload; dietary history current intake also assessed. Apart from examination, specific testing for sarcopenia recommended. For assessment, specifically quantification, gold standard is cross-sectional measurement at L3 obtained computed tomography scan magnetic resonance imaging; dual-energy x-ray absorptiometry good tool especially when appendicular skeletal index calculated. Other more readily available options include phase angle bioelectrical impedance bioimpedance spectroscopy. In function evaluation required, handgrip strength stands primary test purpose; part subjective global included some scores. Finally, Short Physical Performance Battery useful evaluating frailty, multidimensional evaluation, Fried phenotype used. Specifically liver candidates, use Liver Frailty Index

Language: Английский

Citations

3
Malnutrition in solid organ transplant patients: A review of the literature DOI
Heather Lorden,

Jessa Engelken,

Katrina Sprang

et al.

Clinical Transplantation, Journal Year: 2023, Volume and Issue: 37(11)

Published: Sept. 16, 2023

Abstract Screening for malnutrition is of vital importance solid organ transplant candidates to optimize nutrition status before transplant, improve clinical outcomes and inform selection committees nutritional contraindications risks. There are multiple criteria screening tools available determining diagnosis risk. Registered Dietitian Nutritionists use these assessments quantify the severity malnutrition, provide patient‐centered interventions, monitor progression. Many centers in United States utilize American Society Parenteral Enteral Nutrition Academy Dietetics’ Adult Malnutrition Criteria, though there limited research using specifically population. Malnutrition, utilizing other diagnostic tools, has been associated with important complications, including longer length hospital stay, increased mortality, decreased quality life, worsened end‐stage progression, functional status. typically results from sarcopenia cachexia, can ultimately lead frailty, causing further negative impacts on outcomes. This literature review summarizes current provides recommendations future practice implications.

Language: Английский

Citations

2
The Year in Cardiothoracic Transplant Anesthesia: Selected Highlights From 2022 Part I: Lung Transplantation DOI
Andrew Courtwright,

Alice M. Whyte,

Jagan Devarajan

et al.

Journal of Cardiothoracic and Vascular Anesthesia, Journal Year: 2024, Volume and Issue: 38(11), P. 2516 - 2545

Published: May 8, 2024

Language: Английский

Citations

0
The Procalcitonin Combined with C-Reactive Protein/Albumin Ratio as a Predictor of Mortality in Patients After Lung Transplantation DOI Creative Commons
Chenhao Xuan, Dapeng Wang, Song Wang

et al.

Intensive Care Research, Journal Year: 2023, Volume and Issue: 3(3), P. 221 - 228

Published: July 26, 2023

Abstract Background The Procalcitonin (PCT) and C-reactive protein (CRP)/albumin ratio have recently been used to predict early prognosis for intensive care unit (ICU) patients undergoing major surgery. But there were few clinical studies in after lung transplantation (LTX). Aim/Purpose purpose of this study was identify the association between PCT combined with CRP/albumin 30-day mortality accuracy LTX. Method From January 1, 2016 December 2020, data 77 LTX who died within 30 days retrospectively collected, we randomly collected 87 survived more than ROC curve evaluate prognostic value predicting at ICU admission, Cox proportional hazard model analysis risk factors, subgroup analyses conducted. Results Postoperative PCT, CRP, albumin, ratio, atrial fibrillation, primary graft dysfunction (PGD) grade, hours postoperative mechanical ventilation (MV) length stay survivor non-survivor had a significant difference . On regression analysis, both [HR 1.02 (1.00–1.05), P = 0.037] 1.438 (1.26–1.65), < 0.001] independent predictors mortality. In all LTX, area under (AUC) 0.76 (95% CI 0.69–0.83). AUC 0.83 0.75–0.91) interstitial pulmonary fibrosis (IPF). Conclusion could be predictor outcomes predictive efficacy better IPF.

Language: Английский

Citations

0