The Impact of Maternal Passive Tobacco Smoke on Neonatal Myocardiopathy in Mice DOI
Naseer Kawish, Muddasir Hassan Abbasi, Muhammad Babar Khawar

et al.

Birth Defects Research, Journal Year: 2024, Volume and Issue: 116(11)

Published: Nov. 1, 2024

ABSTRACT Background Tobacco smoke has a global impact, particularly on pregnant women and their newborns. An emerging body of research suggests that passive tobacco smoking is significant contributor to congenital cardiovascular disorders (CVDs). Aim the Study This study aimed mimic effects (PTS) neonates exposed throughout gestational period. Methods Female mice (DPC = 0) were PTS; 24 cigarettes/day with an interval 10 min between each cigarette in specialized chamber from conception birth. Histopathological analysis was employed evaluate PTS‐induced cardiac damage neonates. Results The results revealed alterations cell structure, namely, widened interstitial spaces, hemorrhage, pyknotic nuclei, inflammatory infiltration, collagen deposition, fibrosis. Conclusion Maternal exposure PTS during pregnancy may lead neonatal myocardiopathy.

Language: Английский

Hidden blood loss and bleeding characteristics in children with congenital scoliosis undergoing spinal osteotomies DOI Creative Commons
Arimatias Raitio, Susanna Heiskanen, Venla Soini

et al.

International Orthopaedics, Journal Year: 2024, Volume and Issue: 48(6), P. 1569 - 1577

Published: Jan. 17, 2024

Spinal osteotomies are often essential in the treatment of congenital scoliosis. Risk factors for bleeding these patients needing extracavitatory approaches, especially hidden blood loss, sparsely investigated. We aimed to investigate characteristics and loss paediatric undergoing spinal

Language: Английский

Citations

4
Increased Prevalence of Skeletal Anomalies on Ultrasound Evaluation of Buprenorphine-Exposed Human Fetuses DOI

Margaret E. Dean,

Helen Mistler,

Lori L. Moore

et al.

Southern Medical Journal, Journal Year: 2025, Volume and Issue: 118(1), P. 39 - 44

Published: Jan. 1, 2025

In this study, buprenorphine was the primary source of maternal opioid exposure at time initial prenatal evaluation. Current recommendations advise that level II ultrasounds be performed in patients with substance use disorders. For some patients, distance, transportation, and costs associated obtaining from a specialist pose significant barriers. This study thus undertaken to evaluate value buprenorphine-exposed pregnancies.

Language: Английский

Citations

0
Association between disease activity of rheumatoid arthritis and maternal and fetal outcomes in pregnant women: a systematic review and meta-analysis DOI Creative Commons

Jiamin Lv,

Li Xu, Shuhui Mao

et al.

BMC Pregnancy and Childbirth, Journal Year: 2023, Volume and Issue: 23(1)

Published: Oct. 11, 2023

Abstract Background A meta-analysis has compared the pregnancy outcomes between women with and without RA, while effect of disease severity on within RA not been explored. Therefore, we performed a systematic review to assess association activity outcomes. Methods Four English databases (Pubmed, Embase, Cochrane Library, Web Science) three Chinese (China National Knowledge Infrastructure [CNKI], VIP, Wan Fang) was searched for eligible studies up August 13, 2023. Cochran’s Q test I 2 statistic were used heterogeneity included studies. The odds ratio (OR) (for counting data) weighted mean difference (WMD) measurement calculated 95% confidence intervals (95%CIs) using random-effect model (I ≥ 50%) or fixed-effect < 50%). Subgroup analysis based study design regions explore sources heterogeneity. Sensitivity all publication bias assessed Begg’s test. Results total 41 articles finally included. had higher suffer from preeclampsia, gestational diabetes, spontaneous abortion, cesarean delivery (all P 0.05). infants born mother showed risk stillbirth, SGA, LBW, congenital abnormalities, diabetes type 1, asthma high significantly associated (OR: 2.29, 95%CI: 1.02–5.15) premature 5.61, 2.20–14.30). Conclusions High adverse outcomes, suggesting that it important control who prepared pregnancy.

Language: Английский

Citations

9
Predictive factors and adverse perinatal outcomes associated with maternal smoking status DOI Creative Commons
Shereen Hamadneh, Jehan Hamadneh, Esraa Alhenawi

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Feb. 10, 2024

Abstract To identify risk factors for smoking among pregnant women, and adverse perinatal outcomes women. A case–control study of singleton full-term women who gave birth at a university hospital in Jordan June 2020. Pregnant were divided into three groups according to their status, active, passive, non-smokers. They interviewed using semi-structured questionnaire that included demographic data, current pregnancy history, neonatal outcomes. Low-level maternal education, unemployment, secondary antenatal care, having husband identified as smoke exposure The cesarean section was ninefold higher nulliparous Women with low family income, those did not receive information about the hazards smoking, unemployed passive multiparty raised intensive care unit admission active This increased lower levels inactive income by 25 times compared level education. Smoking is associated Appropriate preventive strategies should address modifiable during pregnancy.

Language: Английский

Citations

2
Maternal risk factors for congenital vertebral formation and mixed defects: A population-based case–control study DOI Creative Commons
Susanna Heiskanen, Ilkka Helenius, Johanna Syvänen

et al.

Journal of Children s Orthopaedics, Journal Year: 2024, Volume and Issue: 18(3), P. 340 - 345

Published: March 20, 2024

Background: The etiology and risk factors of congenital vertebral anomalies are mainly unclear in isolated cases. Also, there no reports on the for different subgroups anomalies. Therefore, we assessed identified potential maternal these hypothesized that diabetes, other chronic diseases, smoking, obesity, medication early pregnancy would increase Methods: All cases with were Finnish Register Congenital Malformations from 1997 to 2016 this nationwide register-based case–control study. Five matched controls without malformations randomly selected. Analyzed included age, body mass index, parity, history miscarriages, prescription drug purchases pregnancy. Results: register search 256 malformations. After excluding 66 syndromic cases, 190 non-syndromic (74 formation defects, 4 segmentation 112 mixed anomalies) Maternal smoking was a significant factor defects (adjusted odds ratio 2.33, 95% confidence interval 1.21–4.47). pregestational diabetes 8.53, 2.33–31.20) rheumatoid arthritis 13.19, 1.31–132.95) associated Conclusion: an increased increases represents avoidable scoliosis. Level evidence: III

Language: Английский

Citations

0
The Impact of Maternal Passive Tobacco Smoke on Neonatal Myocardiopathy in Mice DOI
Naseer Kawish, Muddasir Hassan Abbasi, Muhammad Babar Khawar

et al.

Birth Defects Research, Journal Year: 2024, Volume and Issue: 116(11)

Published: Nov. 1, 2024

ABSTRACT Background Tobacco smoke has a global impact, particularly on pregnant women and their newborns. An emerging body of research suggests that passive tobacco smoking is significant contributor to congenital cardiovascular disorders (CVDs). Aim the Study This study aimed mimic effects (PTS) neonates exposed throughout gestational period. Methods Female mice (DPC = 0) were PTS; 24 cigarettes/day with an interval 10 min between each cigarette in specialized chamber from conception birth. Histopathological analysis was employed evaluate PTS‐induced cardiac damage neonates. Results The results revealed alterations cell structure, namely, widened interstitial spaces, hemorrhage, pyknotic nuclei, inflammatory infiltration, collagen deposition, fibrosis. Conclusion Maternal exposure PTS during pregnancy may lead neonatal myocardiopathy.

Language: Английский

Citations

0