Structure and Functional Characteristics of Novel Polyurethane/Ferrite Nanocomposites with Antioxidant Properties and Improved Biocompatibility for Vascular Graft Development DOI Open Access
Marija V. Pergal, Jelena Brkljačić, Dana Vasiljević-Radović

et al.

Polymers, Journal Year: 2025, Volume and Issue: 17(2), P. 152 - 152

Published: Jan. 9, 2025

Novel ferrite/polyurethane nanocomposites were synthesized using the in situ polymerization method after addition of different spinel nanoferrite particles (copper, zinc, and copper–zinc) examined as potential coatings for medical devices implants vascular tissue engineering. The influence type on structure functional characteristics polyurethane composites was investigated by FTIR, SWAXS, AFM, TGA, DSC, nanoindentation, swelling behavior, water contact angle, absorption measurements. Biocompatibility evaluated examining cytotoxicity adhesion human endothelial cells fibroblasts onto prepared performing a protein adsorption test. antioxidant activity detected UV–VIS spectroscopy 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging assay. Embedding types nanoparticles matrix increased phase mixing, ability, DPPH scavenging, decreased surface roughness, differently affected stiffness materials. composite with zinc ferrite showed improved mechanical properties, hydrophilicity, cell adhesion, similar thermal stability, but lower roughness crosslinking density compared to pristine matrix. vitro biocompatibility evaluation demonstrates that all are non-toxic, exhibit good hemocompatibility, promote recommends their use biocompatible materials development implants.

Language: Английский

Structure and Functional Characteristics of Novel Polyurethane/Ferrite Nanocomposites with Antioxidant Properties and Improved Biocompatibility for Vascular Graft Development DOI Open Access
Marija V. Pergal, Jelena Brkljačić, Dana Vasiljević-Radović

et al.

Polymers, Journal Year: 2025, Volume and Issue: 17(2), P. 152 - 152

Published: Jan. 9, 2025

Novel ferrite/polyurethane nanocomposites were synthesized using the in situ polymerization method after addition of different spinel nanoferrite particles (copper, zinc, and copper–zinc) examined as potential coatings for medical devices implants vascular tissue engineering. The influence type on structure functional characteristics polyurethane composites was investigated by FTIR, SWAXS, AFM, TGA, DSC, nanoindentation, swelling behavior, water contact angle, absorption measurements. Biocompatibility evaluated examining cytotoxicity adhesion human endothelial cells fibroblasts onto prepared performing a protein adsorption test. antioxidant activity detected UV–VIS spectroscopy 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging assay. Embedding types nanoparticles matrix increased phase mixing, ability, DPPH scavenging, decreased surface roughness, differently affected stiffness materials. composite with zinc ferrite showed improved mechanical properties, hydrophilicity, cell adhesion, similar thermal stability, but lower roughness crosslinking density compared to pristine matrix. vitro biocompatibility evaluation demonstrates that all are non-toxic, exhibit good hemocompatibility, promote recommends their use biocompatible materials development implants.

Language: Английский

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