Personalised transcranial magnetic stimulation for treatment-resistant depression, depression with comorbid anxiety and negative symptoms of schizophrenia: a narrative review DOI Open Access
Xiao Wei Tan,

Hasvinjit Kaur Gulwant Singh,

Jovi Zheng Jie Koh

et al.

Singapore Medical Journal, Journal Year: 2024, Volume and Issue: 65(10), P. 544 - 551

Published: Oct. 1, 2024

Abstract Transcranial magnetic stimulation (TMS) is a promising intervention for treatment-resistant psychiatric disorders. However, conventional TMS typically utilises one-size-fits-all approach when determining targets. Recent retrospective brain circuit-based analyses using lesion network mapping have suggested that left dorsal lateral prefrontal cortex target has higher efficacy alleviating depression symptoms, dorsomedial more effective anxiety and rostromedial schizophrenia-associated symptoms. Nonetheless, symptom-specific circuit targeting not been tested prospectively. We conducted narrative review of selected literature to investigate individualised discuss potential future directions elucidate the this approach.

Language: Английский

Mechanisms of Action of TMS in the Treatment of Depression DOI
Jonathan Downar, Shan Siddiqi, Anish Mitra

et al.

Current topics in behavioral neurosciences, Journal Year: 2024, Volume and Issue: unknown, P. 233 - 277

Published: Jan. 1, 2024

Language: Английский

Citations

7
Deep Brain Stimulation in the Bed Nucleus of Stria Terminalis and Medial Forebrain Bundle in Two Patients With Treatment‐Resistant Depression and Generalized Anxiety Disorder—A Long‐Term Follow‐Up DOI Creative Commons
Matilda Naesström, Patric Blomstedt, Viktoria Johansson

et al.

Clinical Case Reports, Journal Year: 2025, Volume and Issue: 13(2)

Published: Feb. 1, 2025

ABSTRACT This case report presents positive outcomes from deep brain stimulation (DBS) targeting the bed nucleus of stria terminalis (BNST) in two patients with treatment‐resistant depression and generalized anxiety disorder. DBS effects medial forebrain bundle (MFB) area were unclear. Further research into DBS's efficacy when comorbid is present required.

Language: Английский

Citations

0
An open-source atlas and evidence-based appraisal framework of psychiatric brain stimulation targets generated by causal network mapping DOI Creative Commons
Ryan Webler, Andrew R. Pines,

Nicole Chiulli

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: March 26, 2025

Abstract Causal network mapping is an emerging technique that can be used to derive optimal disorder/symptom-specific brain stimulation targets. This exploits incidental variability in lesion and locations, which creates a natural experiment causal inferences drawn between lesions or modulation of specific circuits clinical outcomes. Circuits identified by mapping, referred as symptom-networks, represent candidate The library psychiatric symptom-networks has grown rapidly recent years, creating need for comprehensive synthesis. present Resource includes open-source atlas 12 we appraise using established evaluative framework. These materials are designed guide the translation symptom-network targets scaffold advancements this quickly developing field.

Language: Английский

Citations

0
Personalised transcranial magnetic stimulation for treatment-resistant depression, depression with comorbid anxiety and negative symptoms of schizophrenia: a narrative review DOI Open Access
Xiao Wei Tan,

Hasvinjit Kaur Gulwant Singh,

Jovi Zheng Jie Koh

et al.

Singapore Medical Journal, Journal Year: 2024, Volume and Issue: 65(10), P. 544 - 551

Published: Oct. 1, 2024

Abstract Transcranial magnetic stimulation (TMS) is a promising intervention for treatment-resistant psychiatric disorders. However, conventional TMS typically utilises one-size-fits-all approach when determining targets. Recent retrospective brain circuit-based analyses using lesion network mapping have suggested that left dorsal lateral prefrontal cortex target has higher efficacy alleviating depression symptoms, dorsomedial more effective anxiety and rostromedial schizophrenia-associated symptoms. Nonetheless, symptom-specific circuit targeting not been tested prospectively. We conducted narrative review of selected literature to investigate individualised discuss potential future directions elucidate the this approach.

Language: Английский

Citations

1