Whole-body magnetic resonance imaging provides accurate staging of diffuse large B-cell lymphoma, but is less preferred by patients DOI Open Access
Lukáš Lambert,

Monika Wagnerova,

Prokop Vodička

et al.

World Journal of Radiology, Journal Year: 2025, Volume and Issue: 17(1)

Published: Jan. 21, 2025

BACKGROUND Whole-body magnetic resonance imaging (wbMRI) allows general assessment of systemic cancers including lymphomas without radiation burden. AIM To evaluate the diagnostic performance wbMRI in staging diffuse large B-cell lymphoma (DLBCL), determine value individual MRI sequences, and assess patients’ concerns with wbMRI. METHODS In this single-center prospective study, adult patients newly diagnosed DLBCL underwent on a 3T scanner [diffusion weighted images background suppression (DWIBS), T2, short tau inversion recovery (STIR), contrast-enhanced T1] fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) (reference standard). The involvement 12 nodal regions extranodal sites was evaluated PET/CT. utility sequences rated five-point scale (0 = not useful, 4 very useful). Patients received questionnaire regarding RESULTS Of 60 eligible patients, 14 (23%) were enrolled completed study. sensitivity (182 sites) 0.84, 0.99 specificity, positive predictive 0.96, negative 0.97, 0.97 accuracy. PET/CT concordant both (13 instances) (κ 1.0). mean scores 3.71 ± 0.73 for DWIBS, 2.64 0.84 T1, 2.14 0.77 STIR, 1.29 T2 (P < 0.0001). mostly concerned about enclosed environment duration examination (27% patients). CONCLUSION exhibited excellent specificity DLBCL. DWIBS T1 as most useful sequences. less willing to undergo second parallel PET/CT, especially owing long environment.

Language: Английский

Whole-body magnetic resonance imaging provides accurate staging of diffuse large B-cell lymphoma, but is less preferred by patients DOI Open Access
Lukáš Lambert,

Monika Wagnerova,

Prokop Vodička

et al.

World Journal of Radiology, Journal Year: 2025, Volume and Issue: 17(1)

Published: Jan. 21, 2025

BACKGROUND Whole-body magnetic resonance imaging (wbMRI) allows general assessment of systemic cancers including lymphomas without radiation burden. AIM To evaluate the diagnostic performance wbMRI in staging diffuse large B-cell lymphoma (DLBCL), determine value individual MRI sequences, and assess patients’ concerns with wbMRI. METHODS In this single-center prospective study, adult patients newly diagnosed DLBCL underwent on a 3T scanner [diffusion weighted images background suppression (DWIBS), T2, short tau inversion recovery (STIR), contrast-enhanced T1] fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) (reference standard). The involvement 12 nodal regions extranodal sites was evaluated PET/CT. utility sequences rated five-point scale (0 = not useful, 4 very useful). Patients received questionnaire regarding RESULTS Of 60 eligible patients, 14 (23%) were enrolled completed study. sensitivity (182 sites) 0.84, 0.99 specificity, positive predictive 0.96, negative 0.97, 0.97 accuracy. PET/CT concordant both (13 instances) (κ 1.0). mean scores 3.71 ± 0.73 for DWIBS, 2.64 0.84 T1, 2.14 0.77 STIR, 1.29 T2 (P < 0.0001). mostly concerned about enclosed environment duration examination (27% patients). CONCLUSION exhibited excellent specificity DLBCL. DWIBS T1 as most useful sequences. less willing to undergo second parallel PET/CT, especially owing long environment.

Language: Английский

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