Siberian Journal of Oncology, Journal Year: 2025, Volume and Issue: 24(1), P. 142 - 149
Published: March 18, 2025
The aim of the study was to analyze effectiveness experimental and clinical photodynamic therapy combined with chemotherapy in treatment malignant premalignant lesions. Material methods . WoS, Scopus, MedLine, RSCI databases have been searched analyzed on this issue, mainly over past 7 years. We found 288 sources pharmaceutical experimental-clinical studies combination compare therapeutic effects monotherapy, which 50 were included review. Results Photodynamic is a new cancer technology that has become increasingly common recent In some cases, it often an alternative method treating when there high risk side complications during traditional treatments such as surgery, radiation chemotherapy. review summarized current aspects performing Despite fact gives best results neoplasms, strategy limitations. One major challenges very little research conducted field. Additional also needed understand mechanisms increasing therapy. challenge reaching effectively deeper tissues remains significant obstacle wider application Therefore, further determine most effective photosensitizers technologies for using non-ionizing radiation. review, we shown strategies nanopharmaceuticals, demonstrated encouraging results. Conclusion improved efficacy reduced deserve comprehensive study.
Language: Английский