Methylmercury in northern pike (Esox lucius) liver and hepatic mitochondria is linked to lipid peroxidation DOI Creative Commons
Kimberley Desjardins, Dominic E. Ponton,

François Bilodeau

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 931, P. 172703 - 172703

Published: May 3, 2024

Methylmercury (MeHg) readily bioaccumulates and biomagnifies in aquatic food webs leading to elevated concentrations fish may thus induce toxicity. Oxidative stress is a suggested effect of MeHg bioaccumulation fish. However, studies on how triggers oxidative wild are scarce. The purpose this study was link the subcellular distribution liver northern pike from St. Maurice River (Québec, Canada), affected by two run-of-river (RoR) dams, artificial wetlands, forest fires, logging activity, lipid peroxidation as an indicator stress. We also evaluated protective effects glutathione (GSH) system selenium (Se), they known alleviate A customized partitioning protocol used separate into metal-sensitive (mitochondria, microsome/lysosome HDP - heat-denatured proteins) metal-detoxified fractions (metal-rich granules HSP heat-stable proteins). examined relation among THg, MeHg, Se concentration livers fractions, hepatic ratio total GSH (GSH

Language: Английский

Methylmercury in northern pike (Esox lucius) liver and hepatic mitochondria is linked to lipid peroxidation DOI Creative Commons
Kimberley Desjardins, Dominic E. Ponton,

François Bilodeau

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 931, P. 172703 - 172703

Published: May 3, 2024

Methylmercury (MeHg) readily bioaccumulates and biomagnifies in aquatic food webs leading to elevated concentrations fish may thus induce toxicity. Oxidative stress is a suggested effect of MeHg bioaccumulation fish. However, studies on how triggers oxidative wild are scarce. The purpose this study was link the subcellular distribution liver northern pike from St. Maurice River (Québec, Canada), affected by two run-of-river (RoR) dams, artificial wetlands, forest fires, logging activity, lipid peroxidation as an indicator stress. We also evaluated protective effects glutathione (GSH) system selenium (Se), they known alleviate A customized partitioning protocol used separate into metal-sensitive (mitochondria, microsome/lysosome HDP - heat-denatured proteins) metal-detoxified fractions (metal-rich granules HSP heat-stable proteins). examined relation among THg, MeHg, Se concentration livers fractions, hepatic ratio total GSH (GSH

Language: Английский

Citations

4