Phage therapeutic delivery methods and clinical trials for combating clinically relevant pathogens DOI
Heba Mohammed Refat M. Selim, Fatma Alzahraa M. Gomaa, Mohammad Y. Alshahrani

et al.

Therapeutic Delivery, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 23

Published: Nov. 15, 2024

The ongoing global health crisis caused by multidrug-resistant (MDR) bacteria necessitates quick interventions to introduce new management strategies for MDR-associated infections and antimicrobial agents' resistance. Phage therapy emerges as an antibiotic substitute its high specificity, efficacy, safety profiles in treating infections. Various vitro vivo studies denoted their eminent bactericidal anti-biofilm potential. This review addresses the latest developments phage regarding attack strategies, formulations, administration routes. It additionally discusses elaborates on status of undergoing clinical trials, challenges encountered usage, explores prospects research application

Language: Английский

Green Synthesis of Zinc Oxide Nanoparticles: Preparation, Characterization, and Biomedical Applications - A Review DOI Creative Commons
Mohamed T. El‐Saadony, Guihong Fang, Si Yan

et al.

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 19, P. 12889 - 12937

Published: Dec. 1, 2024

Abstract: Over the last decade, biomedical nanomaterials have garnered significant attention due to their remarkable biological properties and diverse applications in biomedicine. Metal oxide nanoparticles (NPs) are particularly notable for wide range of medicinal uses, including antibacterial, anticancer, biosensing, cell imaging, drug/gene delivery. Among these, zinc (ZnO) NPs stand out versatility effectiveness. Recently, ZnO become a primary material various sectors, such as pharmaceutical, cosmetic, antimicrobials, construction, textile, automotive industries. can generate reactive oxygen species induce cellular apoptosis, thus underpinning potent anticancer antibacterial properties. To meet growing demand, numerous synthetic approaches been developed produce NPs. However, traditional manufacturing processes often involve economic environmental costs, prompting search more sustainable alternatives. Intriguingly, synthesis methods utilizing plants, plant extracts, or microorganisms emerged ideal producing These green production techniques offer medicinal, economic, environmental, health benefits. This review highlights latest advancements applications, showcasing potential revolutionize field with eco-friendly cost-effective solutions. Keywords: antimicrobial, antioxidant, synthesis, nanomedicine, nanoparticle,

Language: Английский

Citations

9

Frontiers in Bacterial-Based Green Synthesized Nanoparticles (NPs): A Sustainable Strategy for Combating Infectious Plant Pathogens DOI
Amjad Ali, Muhammad Aasım, Kübra Çelık

et al.

Biocatalysis and Agricultural Biotechnology, Journal Year: 2024, Volume and Issue: 60, P. 103293 - 103293

Published: June 27, 2024

Language: Английский

Citations

6

An updated review on the potential of gold nanoparticles for cancer treatment and detection DOI

Shweta Choudhary,

Simran Kaur,

Himanshu Gandhi

et al.

Gold bulletin, Journal Year: 2025, Volume and Issue: 58(1)

Published: March 3, 2025

Language: Английский

Citations

0

Green Biosynthesis of Nanoparticles Using Plant Extracts: Mechanisms, Advances, Challenges, and Applications DOI
Great Iruoghene Edo, Alice Njolke Mafe,

Ali B. M. Ali

et al.

BioNanoScience, Journal Year: 2025, Volume and Issue: 15(2)

Published: March 13, 2025

Language: Английский

Citations

0

Recent development in plant-mediated zinc oxide nanoparticles with biomedical applications DOI

P. Ravi,

Shyamaladevi Babu

Chemical Physics Impact, Journal Year: 2025, Volume and Issue: 10, P. 100870 - 100870

Published: April 14, 2025

Language: Английский

Citations

0

Harnessing the Power of S/N Doped NiO Nanoparticles: Bandgap Tuning for Superior Photocatalytic and Antibacterial Performance DOI

Tariku Tamesgen,

Michael Asfaw Ameya,

Getu Sisay

et al.

Published: April 29, 2025

Abstract Nickel oxide (NiO) has gained attention as a promising photocatalyst, thanks to its high efficiency, photochemical stability, cost-effectiveness, and eco-friendly nature. However, wide band gap rapid electron-hole recombination hinder practical application under visible light. This study synthesized pure NiO nanoparticles (NiO-NPs) sulfur/nitrogen co-doped (S/N-NiO-NPs) via the co-precipitation method. Comprehensive structural optical analyses using UV-Vis, FT-IR, XRD, SEM confirmed successful formation of desired materials. Notably, doping with 4% sulfur 6% nitrogen significantly enhanced charge separation, extended light absorption, narrowed from 3.75 eV 2.50 eV, reduced crystalline size 20.49 nm 17.89 nm. Under optimal conditions (pH 10),40 mg S/N-NiO-NPs achieved an impressive 98.9% degradation 5 ppm methylene blue dye within just 60 min sunlight irradiation, far outperforming NiO-NPs. Additionally, antibacterial evaluations demonstrated superior efficacy, exhibiting inhibition zones of13–17 mm against pathogens such Bacillus cereus, Escherichia coli, Salmonella typhi, Staphylococcus aureus, compared 5–10 observed for These results highlight remarkable potential S/N co-doping in transforming into highly efficient, multifunctional material environmental remediation biomedical applications.

Language: Английский

Citations

0

Advancing neurological disorder detection: ZnFe2O4:Co2+ nanoparticles for highly sensitive electrochemical dopamine sensing and latent fingerprint detection DOI
Nandini Robin Nadar,

J. Deepak,

S.C. Sharma

et al.

Ceramics International, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

0

Phage therapeutic delivery methods and clinical trials for combating clinically relevant pathogens DOI
Heba Mohammed Refat M. Selim, Fatma Alzahraa M. Gomaa, Mohammad Y. Alshahrani

et al.

Therapeutic Delivery, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 23

Published: Nov. 15, 2024

The ongoing global health crisis caused by multidrug-resistant (MDR) bacteria necessitates quick interventions to introduce new management strategies for MDR-associated infections and antimicrobial agents' resistance. Phage therapy emerges as an antibiotic substitute its high specificity, efficacy, safety profiles in treating infections. Various vitro vivo studies denoted their eminent bactericidal anti-biofilm potential. This review addresses the latest developments phage regarding attack strategies, formulations, administration routes. It additionally discusses elaborates on status of undergoing clinical trials, challenges encountered usage, explores prospects research application

Language: Английский

Citations

0