Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(12), P. 2655 - 2655
Published: Dec. 21, 2024
The
human
skin
microbiome,
a
complex
ecosystem
of
microbes,
plays
pivotal
role
in
health.
This
study
aimed
to
investigate
the
impact
two
skincare
regimens,
with
preservatives
(CSPs)
and
preservative-free
(PFPs),
on
microbiome
correlation
quality.
double-blind
randomized
cosmetic
studywith
split-face
design
was
conducted
26
female
participants.
Microbial
diversity
abundance
were
analyzed
using
16S
rRNA
amplicon
sequence
data
quality
utilizing
Antera
3D
camera.
We
confirmed
earlier
studies
identification
major
microbial
taxa
at
genus
level,
including
Cutibacterium
acnes,
Corynebacterium,
Neisseriaceae
as
predominant
part
facial
microbiome.
Furthermore,
profile-based
subgrouping
employed,
which
revealed
that
cluster,
characterized
by
family
its
organism,
exhibited
significant
reduction
folds
count,
fine
lines,
redness
after
application
PFP
compared
CSP.
A
Spearman
analysis
highlighted
between
changes
specific
bacteria
parameters
such
redness,
pores,
texture
context
comparing
Overall,
treatment
demonstrated
greater
number
correlations
bacterial
CSP
treatment,
suggesting
distinct
regimen
Our
provides
insights
into
different
microbiome-centered
approaches
improve
our
understanding
microbiome’s
interplay
but
also
highlights
need
for
larger,
comprehensive
research
further
understand
dermatology.
Clinical Cosmetic and Investigational Dermatology,
Journal Year:
2024,
Volume and Issue:
Volume 17, P. 3013 - 3021
Published: Dec. 1, 2024
Acne
is
a
common
inflammatory
dermatosis.
Although
gender-related
differences
in
prevalence
and
age
of
onset
have
been
documented.
Other
characteristics
acne
not
well
elucidated
yet.
We
compared
skin
lesions,
severity
risk
factors
between
males
females
Chinese.
Investigator-administered
questionnaire
was
used
to
collect
demographic
data,
clinical
feature
from
May
2020
August
2021.
All
participants
were
outpatient
clinics
seven
cities,
China.
A
total
13085
participants,
including
4746
(36.27%)
8339
(63.73%),
aged
8
35
years
old,
completed
the
questionnaire.
The
significantly
younger
than
females(p<0.001).
More
had
comedones(83.76%
vs
75.22%,
p<0.001).
In
contrast,
more
pustules,
cyst/nodules,
scars
severer
lesions(p<0.001).
Moreover,
major
for
constipation,
cosmetics,
dairy
sweet
foods
females,
while
computer
usage/playing
electronic
games,
staying
up
late
at
night,
intake
hot
or
spicy
foods.
experienced
good
response
photodynamic
treatment(79.52%
52.86%,
p<0.05).
appears
earlier
females.
Clinical
features
differ
experience
therapy.
This
survey
carried
out
Chinese
old.
Gender-related
other
ages
regions
remain
be
explored.
Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(12), P. 2655 - 2655
Published: Dec. 21, 2024
The
human
skin
microbiome,
a
complex
ecosystem
of
microbes,
plays
pivotal
role
in
health.
This
study
aimed
to
investigate
the
impact
two
skincare
regimens,
with
preservatives
(CSPs)
and
preservative-free
(PFPs),
on
microbiome
correlation
quality.
double-blind
randomized
cosmetic
studywith
split-face
design
was
conducted
26
female
participants.
Microbial
diversity
abundance
were
analyzed
using
16S
rRNA
amplicon
sequence
data
quality
utilizing
Antera
3D
camera.
We
confirmed
earlier
studies
identification
major
microbial
taxa
at
genus
level,
including
Cutibacterium
acnes,
Corynebacterium,
Neisseriaceae
as
predominant
part
facial
microbiome.
Furthermore,
profile-based
subgrouping
employed,
which
revealed
that
cluster,
characterized
by
family
its
organism,
exhibited
significant
reduction
folds
count,
fine
lines,
redness
after
application
PFP
compared
CSP.
A
Spearman
analysis
highlighted
between
changes
specific
bacteria
parameters
such
redness,
pores,
texture
context
comparing
Overall,
treatment
demonstrated
greater
number
correlations
bacterial
CSP
treatment,
suggesting
distinct
regimen
Our
provides
insights
into
different
microbiome-centered
approaches
improve
our
understanding
microbiome’s
interplay
but
also
highlights
need
for
larger,
comprehensive
research
further
understand
dermatology.