BMC Geriatrics,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: Feb. 4, 2025
Abstract
Background
As
we
age,
staying
physically
active
and
reducing
sedentary
behavior
becomes
crucial.
To
understand
how
to
achieve
this,
factors
related
daily
physical
function
such
as
five-time
sit-to-stand
(STS)
time
should
be
explored.
This
study
aimed
investigate
the
associations
between
STS
time,
self-rated
activity,
function,
health-related
quality
of
life,
mental
health
in
community-dwelling
older
adults
aged
≥
60
years.
Method
Cross-sectional
design
with
self-reported
objectively
measured
data
from
years
(
n
=
819),
acquired
Swedish
National
Study
on
Aging
Care.
Data
was
analyzed
through
multiple
linear
regression.
Results
The
model
(R
2
0.268)
showed
that
predicted
by
grip
strength
(β’
-0.204,
p
<
0.05),
age
0.202,
life
-0.192,
having
fallen
within
preceding
twelve
months
-0.127,
activities
perceived
light
moderate
intensity
-0.121,
one-leg
stand
-0.099,
education
level
-0.092,
0.05).
For
(β
-0.354,
confidence
interval
[CI]
(-0.509)–(-0.199)),
-0.222,
CI
(-0.365)–(-0.078)),
-0.166,
(-0.278)–(-0.053))
were
most
prominent
predictors.
Conclusion
highlights
importance
predicting
adults.
Clinicians
can
use
these
insights
develop
interventions
maintain
regularly
assessing
monitoring
factors.
Future
research
explore
relationship
fall
history,
faster
impact
among
Clinical Nutrition,
Journal Year:
2020,
Volume and Issue:
40(5), P. 3052 - 3061
Published: Nov. 1, 2020
Background
&
aimsBioelectrical
impedance
analysis-derived
phase
angle
(PhA)
has
been
gaining
attention
in
the
clinical
evaluation
of
nutritional
status
because
it
is
thought
to
be
a
proxy
water
distribution
and
body
cell
mass;
also
associated
muscle
strength
an
effective
predictor
different
outcomes.
Since
association
may
expected
between
PhA
sarcopenia
(defined
by
low
skeletal
mass
impaired
function),
aim
this
systematic
review
was
evaluate:
a)
changes
due
sarcopenia;
b)
prevalence
according
values;
c)
derivation
cut-offs
for
detecting
d)
as
predictors
outcomes.MethodsA
research
on
electronic
databases
(PubMed,
Embase,
Scopus
Web
Science)
from
inception
January
31st,
2020
performed
PRISMA
checklist.
Using
PICOS
strategy,
“P”
corresponded
participants
any
age,
gender
or
ethnicity,
“I”
designated
diagnosis
sarcopenia,
“C”
indicated
subjects
without
“O”
PhA,
“S”
selected
all
study
types.
Methodological
quality
assessed
using
National
Institute
Health
(NIH)
assessment
tool.ResultsThrough
initial
literature
search
after
removing
duplicates
excluding
papers
screening
titles
abstracts,
79
potentially
relevant
studies
were
examined.
Thirteen
(7668
subjects)
met
inclusion
criteria.
The
overall
risk
bias
low.
Sarcopenia
with
significant
lower
seven
out
eight,
while
five
six
reported
high
patients
PhA.
Different
cut-off
point
values
4.05
5.05°
have
derived
identification
sarcopenia.
independent
survival
cancer
geriatric
hospitalized
patients.ConclusionsData
demonstrate
that
decreased
sarcopenic
higher
Further
are
needed
determine
what
extent
valuable
and/or
identifying
Ageing Research Reviews,
Journal Year:
2023,
Volume and Issue:
86, P. 101883 - 101883
Published: Feb. 14, 2023
The
definition
of
sarcopenia,
the
age-related
loss
muscle
mass,
has
evolved
since
term's
inception
and
yet
there
is
no
consensus.
Many
identified
definitions
sarcopenia
centre
their
criteria
around
function,
weakness.
Common
variables
to
various
are
appendicular
lean
soft
tissue
mass
(often
called
mass),
grip
strength,
gait
speed.
However,
a
lack
consensus
remains
among
operational
diagnostics
for
this
newly
recognized
disease
may
be
attributed
absence
appropriate
tools
that
accurately
measure
outcomes
interest,
such
as
skeletal
instead
mass.
In
narrative
review,
we
describe
evolution
groups'
address
need
more
accurate
measures
effective,
low-cost
treatments
(i.e.,
resistance
training
diet)
disease.
Consensus
on
what
constitutes
critical
propel
research
in
field
and,
importantly,
provide
prognostic
value
diagnosis
provides
how
patient
would
treated.
BMC Public Health,
Journal Year:
2023,
Volume and Issue:
23(1)
Published: March 14, 2023
Trouble
sleeping
is
one
of
the
major
health
issues
nowadays.
Current
evidence
on
correlation
between
muscle
quality
and
trouble
limited.A
cross-sectional
study
design
was
applied
participants
aged
from
18
to
60
years
in
National
Health
Nutrition
Examination
Survey
(NHANES)
2011-2014
used
for
analysis.
Muscle
index
(MQI)
quantitatively
calculated
as
handgrip
strength
(HGS,
kg)
sum/
arm
appendicular
skeletal
mass
(ASM,
by
using
sum
non-dominant
hand
dominant
hand.
Sleeping
data
obtained
interviews
self-reported
individuals.
The
main
analyses
utilized
weighted
multivariable
logistic
regression
models
according
complex
multi-stage
sampling
NHANES.
Restricted
cubic
spline
model
explore
non-linear
relationship
MQI
sleeping.
Moreover,
subgroup
concerning
sociodemographic
lifestyle
factors
were
conducted
this
study.5143
finally
included
in.
In
fully
adjusted
model,
an
increased
level
significantly
associated
with
a
lower
odds
ratio
sleeping,
OR
=
0.765,
95%
CI:
(0.652,0.896),
p
0.011.
showed
association
However,
it
seemed
that
prevalence
decreased
increasing
until
reached
2.362,
after
which
plateau.
Subgroup
further
confirmed
negative
consistent
robust
across
groups.Overall,
revealed
can
be
reliable
predictor
Maintaining
certain
would
beneficial
sleep
health.
study,
causal
inference
worthy
exploration.
Journal of Applied Physiology,
Journal Year:
2023,
Volume and Issue:
134(4), P. 900 - 914
Published: Feb. 24, 2023
Age-related
skeletal
muscle
atrophy
appears
to
be
a
group-specific
process,
yet
only
few
specific
muscles
have
been
investigated
and
our
understanding
in
this
area
is
limited.
This
review
provides
comprehensive
summary
of
the
available
information
on
age-related
muscle-specific
manner,
nearly
half
which
comes
from
quadriceps.
Decline
size
over
∼50
yr
aging
was
determined
47
cross-sectional
studies
982
young
(∼25
yr)
1,003
old
(∼75
individuals
nine
groups:
elbow
extensors
(−20%,
−0.39%/yr),
flexors
(−19%,
−0.38%/yr),
paraspinals
(−24%,
−0.47%/yr),
psoas
(−29%,
−0.58%/yr),
hip
adductors
(−13%,
−0.27%/yr),
hamstrings
quadriceps
(−27%,
−0.53%/yr),
dorsiflexors
(−9%,
−0.19%/yr),
triceps
surae
(−14%,
−0.28%/yr).
Muscle-specific
rate
also
for
each
subcomponent
hamstrings,
quadriceps,
surae.
Of
all
included
review,
there
more
than
fivefold
difference
between
least
(−6%,
−0.13%/yr,
soleus)
most
(−33%,
−0.66%/yr,
rectus
femoris)
atrophying
muscles.
Muscle
activity
level,
fiber
type,
sex,
timeline
process
appeared
some
influence
atrophy.
Given
large
range
number
that
not
investigated,
could
expand
functional
deficits
develop
with
help
guide
interventions
improve
quality
life
women
men.
Aging,
Journal Year:
2023,
Volume and Issue:
15(10), P. 3904 - 3938
Published: Feb. 22, 2023
Physical
fitness
is
a
well-known
correlate
of
health
and
the
aging
process
DNA
methylation
(DNAm)
data
can
capture
via
epigenetic
clocks.
However,
current
clocks
did
not
yet
use
measures
mobility,
strength,
lung,
or
endurance
in
their
construction.
We
develop
blood-based
DNAm
biomarkers
for
parameters
gait
speed
(walking
speed),
maximum
handgrip
forced
expiratory
volume
one
second
(FEV1),
maximal
oxygen
uptake
(VO2max)
which
have
modest
correlation
with
five
large-scale
validation
datasets
(average
r
between
0.16-0.48).
then
these
parameter
DNAmGrimAge,
mortality
risk
estimate,
to
construct
DNAmFitAge,
new
biological
age
indicator
that
incorporates
physical
fitness.
DNAmFitAge
associated
low-intermediate
activity
levels
across
(
Molecular Aspects of Medicine,
Journal Year:
2024,
Volume and Issue:
97, P. 101270 - 101270
Published: April 6, 2024
The
onset
of
sarcopenia
is
intimately
linked
with
aging,
posing
significant
implications
not
only
for
individual
patient
quality
life
but
also
the
broader
societal
healthcare
framework.
Early
and
accurate
identification
a
comprehensive
understanding
its
mechanistic
underpinnings
therapeutic
targets
paramount
to
addressing
this
condition
effectively.
This
review
endeavors
present
cohesive
overview
recent
advancements
in
research
diagnosis.
We
initially
delve
into
contemporary
diagnostic
criteria,
specifically
referencing
European
Working
Group
on
Sarcopenia
Older
People
(EWGSOP)
2
Asian
(AWGS)
2019
benchmarks.
Additionally,
we
elucidate
assessment
techniques
muscle
strength,
quantity,
physical
performance,
highlighting
tools
such
as
grip
chair
stand
test,
dual-energy
X-ray
Absorptiometry
(DEXA),
bioelectrical
impedance
analysis
(BIA),
gait
speed,
short
performance
battery
(SPPB),
while
discussing
their
inherent
advantages
limitations.
Such
pave
way
early
unequivocal
diagnosis
sarcopenia.
Proceeding
further,
provide
deep-dive
sarcopenia's
pathogenesis,
offering
thorough
examination
associated
signaling
pathways
like
Myostatin,
AMP-activated
protein
kinase
(AMPK),
insulin/IGF-1
Signaling
(IIS),
nuclear
factor
kappa-light-chain-enhancer
activated
B
cells
(NF-κB)
pathways.
Each
pathway's
role
mediation
detailed,
underscoring
potential
target
avenues.
From
perspective,
underscores
pivotal
mitochondrial
dysfunction
sarcopenia,
emphasizing
elements
oxidative
overload,
biogenesis,
mitophagy,
significance.
At
last,
capture
strides
made
treatment,
ranging
from
nutritional
exercise
interventions
pharmacological
supplementation
strategies.
In
sum,
meticulously
synthesizes
latest
scientific
developments
aiming
enhance
precision
clinical
practice
insights
refined
innovative
interventions,
ultimately
contributing
optimized
care
field.
PLoS ONE,
Journal Year:
2021,
Volume and Issue:
16(7), P. e0254262 - e0254262
Published: July 8, 2021
Chronic
neck
pain
(CNP)
incidence
in
the
general
population
is
high
and
contributes
to
a
significant
health
problem.
Kinesiophobia
(fear
of
movement
or
re-injury)
combined
with
emotions
physical
variables
may
play
vital
role
assessing
managing
individuals
CNP.
The
study's
objectives
are
1)
evaluate
relationship
between
kinesiophobia,
intensity,
proprioception,
functional
performance;
2)
determine
if
kinesiophobia
predicts
performance
among
CNP
individuals.
Sixty-four
participants
(mean
age
54.31
±
9.41)
were
recruited
for
this
cross-sectional
study.
following
outcome
measures
evaluated:
using
Tampa
Scale
(TSK),
intensity
visual
analog
scale
(VAS),
cervical
proprioceptive
joint
position
errors
(in
flexion,
extension,
rotation
directions)
range
motion
(CROM)
device
handgrip
strength
as
measure
Baseline®
hydraulic
hand
dynamometer.
showed
strong
positive
correlation
(r
=
0.81,
p<0.001),
mild
moderate
proprioception
(JPE)
left
right
directions
(p<0.05),
but
no
flexion
direction
(p
0.127).
Also,
there
was
negative
-0.65,
p<0.001).
Regression
analysis
proved
that
predictor
(p<0.05).
This
study
infers
pain,
performance.
assessment
should
be
considered
regular
clinical
practice
understand
barriers
can
influence
rehabilitation
outcomes