Alzheimer’s disease susceptibility in African American elders: a classification and regression tree (CART) analysis approach DOI Creative Commons
Sung Seek Moon, Lindsey Anderson, Jinwon Lee

et al.

Journal of Social & Health Sciences, Journal Year: 2023, Volume and Issue: 2, P. 5 - 16

Published: Dec. 31, 2023

Alzheimer's disease (AD) is increasingly prevalent, especially among African American older adults. Despite its widespread nature, accurate and timely diagnosis of AD remains challenging. Addressing the research gap in sociodemographic cardiovascular risk factor associated with adults, this study aimed to identify analyze distinct subgroups within population that are particularly vulnerable AD, thereby contributing development targeted interventions healthcare strategies. This employs a rigorous methodology utilizing classification regression tree (CART) analysis examine data from 2017 Uniform Data Set (UDS). approach enables nuanced susceptibility The CART revealed significant associations between studied factors results indicate presence specific increased vulnerability shaped by varying levels education [relative importance (RI): 100%], antidepressant usage (RI: 83.1%), BMI 71.2%), use antipsychotic agents 35.5%), age smoking cessation 21.5%). These findings underscore culturally for addressing Americans. study's findings, revealing necessity developing policies specifically tailored address these risks.

Language: Английский

The influence of vascular risk factors on cognition among patients over 65 years of age in rural area - preliminary report DOI Creative Commons
Radosław Zachara, Adam Właszczuk, Daria Gendosz de Carrillo

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 20, 2024

Abstract Background: Hypertension (HTN) and diabetes mellitus (DM) are associated with cognitive impairment dementia. Antihypertensive treatment may improve functioning. Elevated blood glucose levels can increase the risk of dementia even in non-DM. Both HTN DM contribute to development Alzheimer’s disease. Aims: The aim this study was assess influence vascular factors on cognition. Methods: conducted south Poland among rural population over 65 years age. 85 patients qualified into were divided groups according presence (n=18), (n=7), or both (n=40). Control group also formed (n=20). Biochemical tests, neurological scales assessment ultrasound examinations conducted. Results: median score for M-ACE scale 3 points lower when coexisted, compared diagnosis solely (25 28 respectively). Considering MMSE results comparable. higher number education correlated better result (median value 11 >25 9 suspected (<22 points) Conclusions: coexistence caused most profound decline functioning patients. Moreover, a protective factor against old Cholesterol uric acid roles still debatable.

Language: Английский

Citations

0
Hypertension and Cognitive Disorders DOI
Kannayiram Alagiakrishnan, Tyler Halverson, Ali Ahmed

et al.

Cardiology in Review, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 23, 2024

Systemic hypertension is possibly the most important modifiable risk factor for development of cognitive decline, both mild impairment (MCI) and dementia. For effective blood pressure (BP) control, it requires proper assessment, using brachial, central, ambulatory measurements, monitoring with a focus on different BP parameters. Different parameters like pulse pressure, mean arterial variability, circadian parameters, nondippers early morning surge, should be considered in evaluation decline due to middle age older adults. Chronic causes vascular remodeling brain leads failure or decline. Achieving specific goals can improve clinical outcomes slow down patients comorbid impairment.

Language: Английский

Citations

0
Sound and Alzheimer’s Disease—From Harmful Noise to Beneficial Soundscape Augmentation and Music Therapy DOI Creative Commons
Goran Belojević

Noise and Health, Journal Year: 2024, Volume and Issue: 26(123), P. 445 - 448

Published: Oct. 1, 2024

Exposure to sound energy may be a risk factor or therapeutic intervention for Alzheimer’s disease (AD). On one hand, noise has harmful effect on people with AD by contributing hearing loss, sleep disturbance, oxidative stress, inflammation, and excitotoxicity. But the other clinical trials nursing home interventions soundscape augmentation involving natural sounds have shown promising results in alleviating psychophysiological symptoms AD. Music therapy, an emerging non-pharmacological treatment, can improve cognition, reduce anxiety depression, enhance self-awareness patients To ensure that music does not become trials, only favorite at levels safe should used. From public health standpoint, countermeasures, sounds, active passive engagement regarded as potentially powerful strategies prevention of

Language: Английский

Citations

0
PENGARUH HIPERTENSI TERHADAP GANGGUAN FUNGSI KOGNITIF PADA LANSIA: SYSTEMATIC REVIEW DOI Creative Commons
Muhammad Farhan,

Yudhie Tanta,

Indri Seta Septadina

et al.

Jurnal Kedokteran dan Kesehatan Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya, Journal Year: 2023, Volume and Issue: 10(3), P. 301 - 308

Published: Aug. 17, 2023

Abstrak Hipertensi dapat terjadi pada semua usia dan jenis kelamin yang berdampak terjadinya berbagai komplikasi, termasuk gangguan kognitif. Studi ini bertujuan untuk mengetahui pengaruh hipertensi terhadap fungsi kognitif, khususnya populasi lanjut usia. dibuat menyesuaikan PRISMA melalui database PubMed, Science Direct, Europe PMC, Willey Online Library, Sage Journal, DOAJ dengan pemfokusan kognitif lansia. Terpilih lima studi terpilih partisipan berjumlah 16.435. Hasil observasi berupa adanya lansia, terutama domain memori kecepatan pemrosesan. Dapat disimpulkan bahwa tingginya tekanan darah, baik sistolik maupun diastolik, berpengaruh Kata kunci: Hipertensi, Gangguan Kognitif, Lansia Abstract Hypertension can occur to every age and gender, be complicated vary diseases, including cognitive impairment. This study aims determine the effects of hypertension impairment in Elder. was adjusted by through Sciece databases with highlighted function elder. Five studies were selected 16.435 participants. The results showed that affect cognitve elder, especially memory processing speed. In conclusion, high blood pressure, either systolic diastolic, affects Keywords: Hypertension, Cognitive Impairment, Elder

Citations

0
PENGARUH HIPERTENSI TERHADAP GANGGUAN FUNGSI KOGNITIF PADA LANSIA: SYSTEMATIC REVIEW DOI Creative Commons
Muhammad Farhan,

Yudhie Tanta,

Indri Seta Septadina

et al.

Jurnal Kedokteran dan Kesehatan Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya, Journal Year: 2023, Volume and Issue: 10(3), P. 301 - 308

Published: Dec. 17, 2023

Hipertensi dapat terjadi pada semua usia dan jenis kelamin yang berdampak terjadinya berbagai komplikasi, termasuk gangguan kognitif. Studi ini bertujuan untuk mengetahui pengaruh hipertensi terhadap fungsi kognitif, khususnya populasi lanjut usia. dibuat menyesuaikan PRISMA melalui database PubMed, Science Direct, Europe PMC, Willey Online Library, Sage Journal, DOAJ dengan pemfokusan kognitif lansia. Terpilih lima studi terpilih partisipan berjumlah 16.435. Hasil observasi berupa adanya lansia, terutama domain memori kecepatan pemrosesan. Dapat disimpulkan bahwa tingginya tekanan darah, baik sistolik maupun diastolik, berpengaruh

Citations

0
Alzheimer’s disease susceptibility in African American elders: a classification and regression tree (CART) analysis approach DOI Creative Commons
Sung Seek Moon, Lindsey Anderson, Jinwon Lee

et al.

Journal of Social & Health Sciences, Journal Year: 2023, Volume and Issue: 2, P. 5 - 16

Published: Dec. 31, 2023

Alzheimer's disease (AD) is increasingly prevalent, especially among African American older adults. Despite its widespread nature, accurate and timely diagnosis of AD remains challenging. Addressing the research gap in sociodemographic cardiovascular risk factor associated with adults, this study aimed to identify analyze distinct subgroups within population that are particularly vulnerable AD, thereby contributing development targeted interventions healthcare strategies. This employs a rigorous methodology utilizing classification regression tree (CART) analysis examine data from 2017 Uniform Data Set (UDS). approach enables nuanced susceptibility The CART revealed significant associations between studied factors results indicate presence specific increased vulnerability shaped by varying levels education [relative importance (RI): 100%], antidepressant usage (RI: 83.1%), BMI 71.2%), use antipsychotic agents 35.5%), age smoking cessation 21.5%). These findings underscore culturally for addressing Americans. study's findings, revealing necessity developing policies specifically tailored address these risks.

Language: Английский

Citations

0