Basidiobolomycosis: Unusual Cause of Colonic Perforation DOI Open Access
Mousa Mobarki,

Nuraddin Alhakami,

Maqsood Ahmad

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 8, 2024

Basidiobolomycosis is a rare fungal infection that triggered by the environmental saprophyte Basidiobolus ranarum. usually presents as an beneath skin and seldom impacts digestive system. There no clear clinical presentation, majority of initial cases are misdiagnosed. We describe 68-year-old man who arrived at emergency room with acute abdomen shock air under diaphragm needed urgent laparotomy colonic resection. The patient, however, died from severe sepsis.

Language: Английский

Hepatic Basidiobolomycosis in a 2-year-old Child: A Case Report DOI Creative Commons

Ahmed Ateik,

Saif Ghabisha,

Ali Almutamaiz

et al.

Journal of Pediatric Surgery Case Reports, Journal Year: 2025, Volume and Issue: unknown, P. 102956 - 102956

Published: Jan. 1, 2025

Language: Английский

Citations

0
Disseminated Gastrointestinal Basidiobolomycosis: A Case Report with Review of Diagnostic Clues DOI Creative Commons
Neda Soleimani, Mohammad Hossein Anbardar, Hamed Nikoupour

et al.

Case Reports in Medicine, Journal Year: 2024, Volume and Issue: 2024(1)

Published: Jan. 1, 2024

Introduction . Basidiobolomycosis is a rare fungal infection caused by an environmental saprophyte, Basidiobolus ranarum It usually presents as chronic subcutaneous infection; however, few cases of gastrointestinal involvement have been reported. The exact transmission route not clear, and diagnosis always requires high index suspicion because it tends to mimic other inflammatory neoplastic conditions. Case Report A 31‐year‐old immunocompetent woman presented with abdominal pain advanced colon mass. She was completely well until about 1.5 years ago, when she underwent bariatric surgery. One year after surgery, developed. colonoscopy showed ulcerative lesion in the descending colon, biopsy favor colitis. Despite immunosuppressive treatment, there no improvement, worsening symptoms, more investigations revealed mass entrapment stomach pancreas. Colonic mucosa trucut just necrosis acute inflammation; thus, exploratory laparotomy colectomy, partial gastrectomy, distal pancreatectomy, left nephrectomy. On pathologic examination, granulomatous inflammation plus Splendore–Hoeppli phenomenon around hyphae, which diagnostic for basidiobolomycosis. Previous pathology slides were reviewed tiny focus After 6 months treatment itraconazole, relatively without any clinical or radiologic abnormalities. Conclusion Our case highlights significance basidiobolomycosis necrotic lesions increased eosinophils, especially presence systemic eosinophilia.

Language: Английский

Citations

1
Navigating treatment for basidiobolomycosis: a qualitative review of 24 cases DOI Creative Commons
Gholamreza Pouladfar,

Samaneh Jahangiri,

Amirhossein Shahpar

et al.

BMC Infectious Diseases, Journal Year: 2024, Volume and Issue: 24(1)

Published: Aug. 12, 2024

Abstract Background and Objectives Zygomycosis, a severe form of fungal infection, is classified into two categories: Mucorales Entomophthorales. Within the Entomophthorales category, Basidiobolomycosis rarely recognized genus that can have significant health implications. Prompt diagnosis appropriate treatment, which includes use antifungal medication surgical procedures, are vital for enhancing prognosis patients. The objective this study to investigate response treatment in patients hospitalized due basidiobolomycosis. Methods We carried out retrospective study, we analyzed data from 49 who were diagnosed with Entomophthorale, at Namazi Hospital, Shiraz, between years 1997 2019. included parameters such as demographic information, clinical symptoms, imaging findings, methods, patient outcomes. Results Out patients, 24 children, predominantly male (83.3%), definitively ages ranged 1 16 years, an average 5.75 years. most frequently observed manifestations abdominal pain (70.8%), fever (54.2%), hematochezia (41.7%), vomiting (20.8%), anorexia (16.7%). Half exhibited failure thrive (FTT), while distension was present 25% cases, palpable mass found 37% primary strategy incorporated interventions complemented by comprehensive regimen. This regimen medications amphotericin B, cotrimoxazole, itraconazole, potassium iodide, voriconazole. These mainly administered combination therapy pattern or monotherapy B. Twenty-two discharged, died complications disease. Conclusion Our findings indicate prevailing modalities generally involve intervention supplemented regimens, including Amphotericin Cotrimoxazole, Potassium Iodide, Itraconazole.

Language: Английский

Citations

0
Unveiling the Uncommon: Gastrointestinal Basidiobolomycosis of the Colon and its Distinctive Splendore-Hoeppli Phenomenon DOI
Nada Shaker,

Ibrahim Mansoor,

Nasir Saleem

et al.

International Journal of Surgical Pathology, Journal Year: 2024, Volume and Issue: unknown

Published: June 7, 2024

Background Basidiobolomycosis is a rare fungal infection caused by Basidiobolus ranarum. Case Presentation A 53-year-old man from Saudi Arabia with known history of diverticulosis presented severe abdominal pain and diarrhea. CT scan revealed circumferential wall thickening the descending sigmoid colon surrounding fat stranding, suggesting diagnosis complicated diverticulitis. Additional thick fluid was observed around affected area. Surgical excision pursued. gross examination two received large bowel segments disclosed marked ulcerated mucosa exudate-covered serosal surfaces adhesions. Microscopic unveiled significant infiltration eosinophils, polymorphonuclear leukocytes, granulomatous inflammation. Thin-walled, broad hyphae Basidiobolus, surrounded eosinophilic material, were identified. Granulomas displayed abundant multinucleated giant cells palisading histiocytes central necrosis or abscess formation. sparse septations, are radiating, intensely cuff (Splendore-Hoeppli phenomenon). These hyphae, visible hematoxylin eosin staining, further highlighted periodic acid-Schiff Gomori methenamine silver staining. Discussion may mimic neoplastic lesions. Histologically, characteristic features include broad, thin-walled septate finding that accentuated Splendore-Hoeppli phenomenon. examination, along special stains such as (PAS) silver, essential for accurate diagnosis. Conclusion Prompt recognition appropriate antifungal therapy vital favorable patient outcomes. This report highlights distinctive to raise awareness understanding this infrequent yet clinically infection.

Language: Английский

Citations

0
Basidiobolomycosis: Unusual Cause of Colonic Perforation DOI Open Access
Mousa Mobarki,

Nuraddin Alhakami,

Maqsood Ahmad

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 8, 2024

Basidiobolomycosis is a rare fungal infection that triggered by the environmental saprophyte Basidiobolus ranarum. usually presents as an beneath skin and seldom impacts digestive system. There no clear clinical presentation, majority of initial cases are misdiagnosed. We describe 68-year-old man who arrived at emergency room with acute abdomen shock air under diaphragm needed urgent laparotomy colonic resection. The patient, however, died from severe sepsis.

Language: Английский

Citations

0