Advances of Stimuli-Responsive Amphiphilic Copolymer Micelles in Tumor Therapy DOI Creative Commons
Yao Wang,

Meng Lin,

Tianfei Fan

et al.

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 20, P. 1 - 24

Published: Dec. 31, 2024

Abstract: Amphiphilic copolymers are composed of both hydrophilic and hydrophobic chains, which can self-assemble into polymeric micelles in aqueous solution via the hydrophilic/hydrophobic interactions. Due to their unique properties, have been widely used as drug carriers. Poorly soluble drugs be covalently attached polymer chains or non-covalently incorporated micelles, with improved pharmacokinetic profiles enhanced efficacy. In recent years, stimuli-responsive amphiphilic copolymer attracted significant attention. These respond specific stimuli, including physical triggers (light, temperature, etc). chemical stimuli (pH, redox, physiological factors (enzymes, ATP, Under these structures properties change, enabling targeted therapy controlled release tumors. strategies offer new avenues approaches enhance tumor efficacy reduce side effects. We will review applications different types therapy, aiming provide valuable guidance for future research directions clinical translation. Keywords: stimuli-responsive, delivery system

Language: Английский

IR SPECTRA OF PROFLAVINE IN COMPLEX WITH POLYETHYLENE GLYCOL. QUANTUM CHEMISTRY INVESTIGATION VS EXPERIMENTAL DATA DOI

Eugen Dukhopelnikov,

Ekaterina Bereznyak, Vladimir V. Ivanov

et al.

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 142003 - 142003

Published: March 1, 2025

Language: Английский

Citations

0
Nanoparticle Contrast Agents for Photon‐Counting Computed Tomography: Recent Developments and Future Opportunities DOI
Laxman Devkota, Rohan Bhavane, Cristian T. Badea

et al.

Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology, Journal Year: 2025, Volume and Issue: 17(1)

Published: Jan. 1, 2025

ABSTRACT The clinical availability of photon‐counting computed tomography (PCCT) has ushered in a new era CT imaging. Spectral imaging coupled with superior contrast resolution, and ultrahigh spatial resolution (200 μm) offered by PCCT the potential to revolutionize value‐driven multicolor generated excitement, renewed interest, novel agent development for comprehensive disease interrogation, prediction monitoring treatment outcomes. Nanoparticles provide versatile powerful platform next generation agents spectral PCCT. In this article, we review recent developments use nanoparticle We also discuss future research translational opportunities nanoparticle‐based enabled advent describe key considerations their translation.

Language: Английский

Citations

0
Engineering colloidal systems for cell manipulation, delivery, and tracking DOI
Olga A. Sindeeva, Zhanna V. Kozyreva, Arkady S. Abdurashitov

et al.

Advances in Colloid and Interface Science, Journal Year: 2025, Volume and Issue: 340, P. 103462 - 103462

Published: Feb. 27, 2025

Language: Английский

Citations

0
Advances of Stimuli-Responsive Amphiphilic Copolymer Micelles in Tumor Therapy DOI Creative Commons
Yao Wang,

Meng Lin,

Tianfei Fan

et al.

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 20, P. 1 - 24

Published: Dec. 31, 2024

Abstract: Amphiphilic copolymers are composed of both hydrophilic and hydrophobic chains, which can self-assemble into polymeric micelles in aqueous solution via the hydrophilic/hydrophobic interactions. Due to their unique properties, have been widely used as drug carriers. Poorly soluble drugs be covalently attached polymer chains or non-covalently incorporated micelles, with improved pharmacokinetic profiles enhanced efficacy. In recent years, stimuli-responsive amphiphilic copolymer attracted significant attention. These respond specific stimuli, including physical triggers (light, temperature, etc). chemical stimuli (pH, redox, physiological factors (enzymes, ATP, Under these structures properties change, enabling targeted therapy controlled release tumors. strategies offer new avenues approaches enhance tumor efficacy reduce side effects. We will review applications different types therapy, aiming provide valuable guidance for future research directions clinical translation. Keywords: stimuli-responsive, delivery system

Language: Английский

Citations

2