Advances and prospects of precision nanomedicine in personalized tumor theranostics DOI Creative Commons
Yuhang Mao,

Juanping Xie,

Fang Yang

et al.

Frontiers in Cell and Developmental Biology, Journal Year: 2024, Volume and Issue: 12

Published: Dec. 5, 2024

Tumor, as the second leading cause of death globally, following closely behind cardiovascular diseases, remains a significant health challenge worldwide. Despite existence various cancer treatment methods, their efficacy is still suboptimal, necessitating development safer and more efficient strategies. Additionally, advancement personalized therapy offers further possibilities in treatment. Nanomedicine, promising interdisciplinary field, has shown tremendous potential prospects diagnosis cancer. As an emerging approach oncology, application nanomedicine primarily focuses on targeted drug delivery systems such passive targeting delivery, active environmentally responsive well imaging diagnostics tumor biomarker detection, cell vivo imaging. However, it faces challenges regarding safety, biocompatibility, other issues. This review aims to explore advances use nanomaterials field investigate developing therapies care, providing direction for clinical translation application.

Language: Английский

Biomolecule-based engineered nanoparticles for Cancer Theranostics DOI

Narayanan Parthasarathy,

Ramar Thangam, Babu Rithisa

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 530, P. 216489 - 216489

Published: Feb. 3, 2025

Language: Английский

Citations

3
Multifunctional nanoparticles for image-guided drug delivery in nuclear medicine: advancements and applications DOI

Bilal AbdulMajeed Mukhlif,

Muhammad Ikram Ullah, Subasini Uthirapathy

et al.

Journal of Radioanalytical and Nuclear Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 6, 2025

Language: Английский

Citations

2
Current Research in Drug-Free Cancer Therapies DOI Creative Commons

Akshaya Andavar,

Varsha Rajesh Bhagavathi,

J Cousin

et al.

Bioengineering, Journal Year: 2025, Volume and Issue: 12(4), P. 341 - 341

Published: March 26, 2025

Cancer treatment has historically depended on conventional methods like chemotherapy, radiation, and surgery; however, these strategies frequently present considerable limitations, including toxicity, resistance, negative impacts healthy tissues. In addressing challenges, drug-free cancer therapies have developed as viable alternatives, utilizing advanced physical biological to specifically target tumor cells while reducing damage normal This review examines several strategies, such high-intensity focused energy beams, nanosecond pulsed electric fields, photothermal therapy well the use of inorganic nanoparticles promote selective apoptosis. We also investigate significance targeting microenvironment, precision medicine, immunotherapy in progression personalized therapies. Although approaches demonstrate significant promise, challenges scalability, safety, regulatory obstacles must be resolved for clinical application. paper presents an overview current research therapies, emphasizing recent advancements, underlying scientific principles, steps required implementation.

Language: Английский

Citations

1
Modern tumor imaging models for rodents: potential and prospects in translational medicine DOI Creative Commons
Anastasia A. Fadeeva,

ZM Osipova,

TV Chepurnykh

et al.

Bulletin of Russian State Medical University, Journal Year: 2025, Volume and Issue: 2025(2)

Published: March 1, 2025

Rodent neoplastic process models are extensively used in pre-clinical practice to assess the dynamics of tumor development and test anti-cancer drugs, which ensures flexibility choosing both basic advanced personalized for researchers. Various modern model imaging methods considered, including fluorescence bioluminescence imaging, enable comprehensive assessment, from qualitative evaluation vivo monitoring. We believe that autonomous bioluminescent systems mammalian cells will provide new possibilities noninvasive animal physiological processes, long-term monitoring progression.

Language: Английский

Citations

0
Nanotechnology-Driven Drug Delivery in Rheumatoid Arthritis: Current Trends, Key Challenges, and Future Perspectives DOI Open Access
Minal Narkhede,

Shruti Nanaji Bhamare

Biosciences Biotechnology Research Asia, Journal Year: 2025, Volume and Issue: 22(1), P. 1 - 21

Published: March 25, 2025

ABSTRACT: Rheumatoid arthritis is a chronic autoimmune disorder that causes progressive joint damage and disability, significantly impacting patients' quality of life. In this Traditional treatment, including disease-modifying ant rheumatic drugs biologics often fall short in targeting the disease with precision, leading to side effects limited efficacy. We selected Nanotechnology which offers promising solution for improving drug delivery enhancing therapeutic outcomes RA management. This review explores current trends future prospects nanotechnology-based systems treatment. discuss various types nanocarriers, such as nanoparticles, liposomes, micelles, their ability enhance targeted biologic agents small molecules. Additionally, we examine potential "smart" nanomaterials respond disease-specific stimuli controlled release, thereby reducing systemic toxicity. The integration nanotechnology biologics, gene therapies, combination treatments highlighted strategy efficacy minimizing adverse effects. Finally, addresses ongoing challenges directions, need more extensive clinical trials ensure safety effectiveness these innovative therapies patients.

Language: Английский

Citations

0
Iron oxide based magnetic nanoparticles for hyperthermia, MRI and drug delivery applications: a review DOI Creative Commons
Rizwana Ghazi,

Talib K. Ibrahim,

Jamal Abdul Nasir

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(15), P. 11587 - 11616

Published: Jan. 1, 2025

Iron-oxide nanoparticles (IONPs) have garnered substantial attention in both research and technological domains due to their exceptional chemical physical properties.

Language: Английский

Citations

0
A Review on Synthesis, Functionalization, and Theranostic Prospects of Holmium Nanoparticles DOI Creative Commons
Retna Putri Fauzia,

Ayu Jelita Sinambela,

Zahra Afriani

et al.

Results in Surfaces and Interfaces, Journal Year: 2025, Volume and Issue: unknown, P. 100545 - 100545

Published: May 1, 2025

Language: Английский

Citations

0
Advancing the potential of nanoparticles for cancer detection and precision therapeutics DOI

Muhammad Naeem Kiani,

Hamza Khaliq,

Muhammad Abubakar

et al.

Medical Oncology, Journal Year: 2025, Volume and Issue: 42(7)

Published: June 4, 2025

Language: Английский

Citations

0
Advances and prospects of precision nanomedicine in personalized tumor theranostics DOI Creative Commons
Yuhang Mao,

Juanping Xie,

Fang Yang

et al.

Frontiers in Cell and Developmental Biology, Journal Year: 2024, Volume and Issue: 12

Published: Dec. 5, 2024

Tumor, as the second leading cause of death globally, following closely behind cardiovascular diseases, remains a significant health challenge worldwide. Despite existence various cancer treatment methods, their efficacy is still suboptimal, necessitating development safer and more efficient strategies. Additionally, advancement personalized therapy offers further possibilities in treatment. Nanomedicine, promising interdisciplinary field, has shown tremendous potential prospects diagnosis cancer. As an emerging approach oncology, application nanomedicine primarily focuses on targeted drug delivery systems such passive targeting delivery, active environmentally responsive well imaging diagnostics tumor biomarker detection, cell vivo imaging. However, it faces challenges regarding safety, biocompatibility, other issues. This review aims to explore advances use nanomaterials field investigate developing therapies care, providing direction for clinical translation application.

Language: Английский

Citations

1