Higher oxidative balance score is associated with a decreased risk of infertility: an analysis of NHANES 2013–2020

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: Feb. 4, 2025

Background Oxidative stress plays a crucial role in the female reproductive system. The oxidative balance score (OBS) is new measure for assessing between antioxidant and pro-oxidative factors diet lifestyle. However, limited studies have explored relationship OBS infertility. Methods We performed cross-sectional study including 2,664 women aged 20–45 years, based on data from 2013–2020 National Health Nutrition Examination Survey (NHANES). was derived 16 dietary components 4 lifestyle factors. used multivariate logistic regression analysis to examine association Results revealed significant negative higher infertility risk, with an odds ratio (OR) of 0.98 (95% CI, 0.95–1.00) after full adjustment. Compared first quartile OBS, second, third, fourth quartiles showed ORs 0.71 0.45–1.11), 0.79 0.51–1.22), 0.57 0.35–0.92), respectively. Similarly, highest had lower risk compared those lowest quartiles, 0.60 0.39–0.94) 0.54 0.32–0.93), Furthermore, subgroup indicated that remained consistent, except among other ethnicities—including multi-racial, college graduate or higher. Conclusion These findings suggest high are associated

Language: Английский

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Association between the composite dietary antioxidant index and risk of endometriosis in women: a national population-based study

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: March 26, 2025

Background Composite dietary antioxidant index (CDAI) has been found protective to women’s health. However, the association between CDAI level and risk of endometriosis in women is unclear. Methods A total 4,153 from National Health Nutrition Examination Survey (NHANES) 2001–2006 were included this cross-sectional study. We evaluated using three logistic regression models restricted cubic spline. Stratified sensitivity analyses also performed. Results Logistic analysis that was inversely associated with development endometriosis. The odds ratio (OR) for each SD increase 0.98 [95%CI: 0.96–0.99]. After dividing into four quartiles, we compared Q1 (−1.89, −1.79), ORs [95%CI] Q2 (−1.79, −0.69), Q3 (−0.69, 1.42) Q4 (1.42, 47.92) 0.94 [0.87, 1.03], 0.95 [0.88, 1.04] 0.83 [0.77, 0.91], respectively, p trend<0.001. Restricted spline showed a negative dose–response relationship risk. In addition, effect on more obvious aged 30–39 years (OR = 0.83, 95% CI 0.69–0.99), gave relatively births 0.82, 071–0.93), lower family income 0.69, 0.54–0.88), Non-Hispanic Black 0.72, 0.58–0.89), less educated 0.52–0.91), smoker 0.74, 0.61–0.89), alcohol drinker 0.86, 0.77–0.97), overweight or obese 0.76, 0.60–0.97), hypertensive 0.60–0.87). Conclusion Our findings may provide valuable insights primary prevention further prospective studies are warranted.

Language: Английский

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Joint association of dietary and lifestyle oxidative balance score with infertility among reproductive-aged US female: a cross-sectional study

Human Fertility, Journal Year: 2025, Volume and Issue: 28(1)

Published: April 15, 2025

Infertility affects one in six individuals globally, with oxidative stress-modifiable through diet and lifestyle-being a key factor female infertility. This study examines associations between dietary/lifestyle Oxidative Balance Scores (OBS) infertility risk reproductive-aged women. Using 2013-2018 NHANES data from 2,447 women aged 20-44, we calculated OBS (16 dietary 4 lifestyle components) reflecting antioxidant vs. pro-oxidant exposure. Higher scores indicate dominance. Weighted logistic regression models adjusted for sociodemographic health covariates revealed an inverse linear relationship: each 1-unit increase correlated 4.7% lower (95% CI: 0.929-0.977, p < 0.001). Women the highest tertile had 6.4% reduced odds versus tertiles 0.897-0.977, = 0.003). Joint analyses showed higher mitigated among low OBS. Results remained consistent across subgroups sensitivity analyses. These findings underscore potential of antioxidant-rich diets healthy lifestyles reducing stress-related infertility, advocating targeted interventions to improve reproductive outcomes.

Language: Английский

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The Importance of Diet in the Treatment of Endometriosis

Women, Journal Year: 2024, Volume and Issue: 4(4), P. 453 - 468

Published: Nov. 18, 2024

The world of science is increasingly looking for answers to the question how specific dietary components affect risk chronic diseases and assessing their potential alleviate severity individual diseases. This research concerns both assessment benefits using those nutritional models. Endometriosis, due its inflammatory nature, also a topic interest among scientists, who seek support course through proper nutrition. In endometriosis, great focused on patterns such as an anti-inflammatory diet, gluten-free low-FODMAP or Mediterranean diet. An diet primarily focuses fresh vegetables, fruits, seeds, nuts, whole grain products, healthy sources protein fats, including mono- polyunsaturated fatty acids, eliminating highly processed meat trans refined sugars. It believed that this type may contribute reducing endometriosis symptoms help reduce inflammation. aim review identify main trends in field diets supporting treatment last 5 years.

Language: Английский

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