Pomegranate (Punica granatum L.) Extract Effects on Inflammaging

Molecules, Journal Year: 2024, Volume and Issue: 29(17), P. 4174 - 4174

Published: Sept. 3, 2024

Pomegranate is a notable source of nutrients, containing considerable proportion organic acids, polysaccharides, vitamins, fatty and polyphenols such as flavonoids, phenolic tannins. It also rich in nutritionally important minerals chemical elements K, P, Na, Ca, Mg, N. The presence several bioactive compounds metabolites pomegranate has led to its incorporation into the functional food category, where it used for numerous therapeutic properties. Pomegranate’s have shown antioxidant, anti-inflammatory, anticancer effects. Aging process characterized by chronic accumulation damages, progressively compromising cells, tissues, organs over time. Inflammaging chronic, subclinical, low-grade inflammation that occurs during aging linked many age-related diseases. This review aims summarize discuss evidence benefits extract slow processes intervening mechanisms underlying inflammaging. These studies mainly concern neurodegenerative skin diseases, while other fields application need be more practical. Furthermore, no human demonstrated anti-inflammaging effects pomegranate. In future, supplementation with extracts, polyphenols, or urolithins could represent valuable low-risk complementary therapy patients difficult-to-manage well valid alternative topical systemic treatment pathologies.

Language: Английский

Allergic rhinitis in children is associated with high serum levels of zonulin

International Journal of Pediatric Otorhinolaryngology, Journal Year: 2025, Volume and Issue: unknown, P. 112350 - 112350

Published: April 1, 2025

Language: Английский