Opportunities for optimizing therapy in the metabolic phenotype of osteoarthritis DOI Creative Commons
I. B. Bashkova, Е. И. Бусалаева

Meditsinskiy sovet = Medical Council, Journal Year: 2025, Volume and Issue: 3, P. 134 - 143

Published: April 12, 2025

Osteoarthritis (OA) is an extremely heterogeneous disease. Identifying a specific disease phenotype will help the practitioner optimize approaches to diagnosis and treatment. The metabolic of OA associated with greatest polyand comorbidity, which significantly limit choice number drugs often used in treatment this joint pathology. presented clinical observation demonstrates difficulties care patient combination eleven somatic diseases at same time, one was OA. Care tactics suggest, on hand, justified polypragmasy, other low adherence long–term use large drugs. presence many comorbid diseases, particular coronary heart disease, history stroke, suggest complete rejection nonsteroidal anti-inflammatory (with exception local forms). Regular therapy bioactive extract from small marine fish last two years has made it possible achieve improvement and, probably, prevent radiographic progression knee delay replacement surgery.

Language: Английский

Adipose derived stem cells – Sources, differentiation capacity and a new target for reconstructive and regenerative medicine DOI
Małgorzata Suchanecka, Joanna Grzelak,

Maryam Farzaneh

et al.

Biomedicine & Pharmacotherapy, Journal Year: 2025, Volume and Issue: 186, P. 118036 - 118036

Published: April 8, 2025

Language: Английский

Citations

0

Opportunities for optimizing therapy in the metabolic phenotype of osteoarthritis DOI Creative Commons
I. B. Bashkova, Е. И. Бусалаева

Meditsinskiy sovet = Medical Council, Journal Year: 2025, Volume and Issue: 3, P. 134 - 143

Published: April 12, 2025

Osteoarthritis (OA) is an extremely heterogeneous disease. Identifying a specific disease phenotype will help the practitioner optimize approaches to diagnosis and treatment. The metabolic of OA associated with greatest polyand comorbidity, which significantly limit choice number drugs often used in treatment this joint pathology. presented clinical observation demonstrates difficulties care patient combination eleven somatic diseases at same time, one was OA. Care tactics suggest, on hand, justified polypragmasy, other low adherence long–term use large drugs. presence many comorbid diseases, particular coronary heart disease, history stroke, suggest complete rejection nonsteroidal anti-inflammatory (with exception local forms). Regular therapy bioactive extract from small marine fish last two years has made it possible achieve improvement and, probably, prevent radiographic progression knee delay replacement surgery.

Language: Английский

Citations

0