Role of Melatonin as an Adjunctive Treatment for Depression and Cognitive Impairment in Hemodialysis Patients: A Randomized, Double-Blind Clinical Trial DOI Creative Commons

Shima Hatamkhani,

Sara Khanipour Roshan, Afshin Shiva

et al.

Iranian Journal of Psychiatry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 29, 2024

Objective: Chronic kidney disease (CKD) is a pervasive health issue associated with various complications, including cognitive impairment and depression among patients undergoing hemodialysis. This study aimed to assess the impact of melatonin on function in hemodialysis patients. Method : A randomized, double-blinded, placebo-controlled clinical trial was conducted 50 patients, half receiving 3 mg daily other placebo for two months. Depression were evaluated using Beck Inventory (BDI) Mini-Mental State Examination (MMSE) questionnaire, respectively. Quantitative variables analyzed t-test. The Chi-square test also qualitative variables. data by covariance analysis before after intervention. Results: Hypertension most prevalent underlying condition participants, affecting 40% intervention group. group exhibited baseline depressive symptoms (mean BDI score: 16.12 ± 7.12), which significantly improved post-intervention (13.6 6.6). Notably, both control groups demonstrated significant reductions symptoms, as assessed paired t-tests (P = 0.033 P 0.02, respectively). Cognitive function, measured MMSE, (1.28 0.81 melatonin, 1.52 0.1 placebo), within-group differences 0.048 0.002, ANCOVA revealed no between-group scores (F(1,47) 0.196, 0.66, partial eta-squared 0.004). MMSE 0.003, 0.954, 0.00) post-intervention. Conclusion: While this did not demonstrate effects positive changes observed, warranting further research optimize treatment regimens explore potential therapeutic benefits patient population.

Language: Английский

Prevalence and determinants of depression and its association with social support among cancer patients: implications for enhancing oncology care DOI Creative Commons
Sameer A. Alkubati, Abdulsalam Halboup, Mohamed Ali Zoromba

et al.

BMC Psychology, Journal Year: 2025, Volume and Issue: 13(1)

Published: March 12, 2025

Early detection of depression in cancer patients is essential for improving health outcomes. This study assessed the prevalence and determinants among examined its association with social support. A cross-sectional was conducted at Al Amal Cancer Center, Al-Thawra Hospital, Hodeida City, Yemen (January–March 2023). Data on sociodemographic characteristics, (Patient Health Questionnaire, PHQ-9), support (Oslo Social Support Scale, OSSS-3) were collected. Multivariate binary logistic regression identified significant factors, Pearson's correlation used to assess relationship between depression. p value < 0.05 indicated statistical significance. Depression incidence 55% (n = 192). analysis revealed that married (AOR 9.472, 0.001) divorced/widowed 11.649, more likely have than single individuals were. Higher education (diploma or above) protective 0.071, 0.001). Elevated lipid levels linked a lower risk 0.189, 0.003), family history 4.239, 0.001), longer disease duration (> 4 years) 3.197, 0.006), difficulty activities 8.704, increased risk. negative found (r − 0.237, Over half experience depression, which influenced by marital status, education, disease-related factors. significantly mitigates Enhancing integrating mental assessments psychiatric professionals oncology care emotional well-being overall quality life patients.

Language: Английский

Citations

0
Prevalence of Depression and Its Associated Factors Among Hemodialysis Patients in Hodeida City, Yemen [Letter] DOI Creative Commons
Song Wang, Jing Song, Xiaolian Jiang

et al.

Journal of Multidisciplinary Healthcare, Journal Year: 2024, Volume and Issue: Volume 17, P. 1041 - 1042

Published: March 1, 2024

Prevalence of Depression and Its Associated Factors Among Hemodialysis Patients in Hodeida City, Yemen" by Alkubati SA et al. 1 It is a valuable interesting research.The strengths this study are as follows: (1) This the first to identify prevalence depression its associated factors among Yemeni hemodialysis (HD) patients who facing multiple war-related crises or ongoing political conflict have been overlooked, remain undiagnosed receive limited care.Paying more attention mental health HD developing countries regions (eg, Yemen) providing tailored psychological support nursing care mission healthcare professionals; (2) The employed OpenEpi website formula calculate sample size, which provided new insight into size estimation methods; 2 (3) authors conducted in-depth discussion, fully compared their research findings with previous studies performed other China, Jordan, Saudi Arabia, Lebanon, Malaysia, Palestine, etc), analyzed specific reasons for these differences.Nevertheless, encountered certain constraints some areas improvement: may consider using G*Power version 3.1.9.7 software 3 very quick convenient software; There two text that need be corrected: (a) Page 694, Sex variable Table has incorrect N value female.After correction, shown letter.(b) 693, description "The results showed only female (odds ratio (OR)=0.298;95% confidence interval (CI)=0.132-0.674;p=0.004)" inconsistent page 695, it should described (OR)=3.352;95% (CI) = 1.484-7.570;p=0.004)"; variables included binary logistic regression analysis relatively limited.Some professionally significant related were not

Language: Английский

Citations

2
Predictors to Poor Quality of Life Among Patients with Heart Failure and Its Correlation with Their Medication Adherence: Finding for Healthcare Improvement and Follow-Up DOI Creative Commons
Sameer A. Alkubati,

Homoud Khaled Aleyadah,

Mohammad Alboliteeh

et al.

Patient Preference and Adherence, Journal Year: 2024, Volume and Issue: Volume 18, P. 2545 - 2557

Published: Dec. 1, 2024

Understanding medication adherence and its relationship with quality of life (QoL) is essential for improving health outcomes in patients heart failure (HF).

Language: Английский

Citations

2
Perceived Health Needs, Social Support, and Depression Among Patients with Myocardial Infarction: A Cross-Sectional Study DOI Open Access
Bushra Alshammari,

Fatmah Awad Alrshedy,

Awatif Alrasheeday

et al.

Healthcare, Journal Year: 2024, Volume and Issue: 12(24), P. 2570 - 2570

Published: Dec. 20, 2024

Cardiovascular diseases are the leading cause of mortality globally. Myocardial infarction (MI), a major type cardiovascular disease, presents long-term challenges for patients. Recognizing patients' perceived health needs and factors that influence them is crucial providing comprehensive care improving outcomes. This paper explores needs, levels depression, social support among MI patients, as well investigates correlations between these factors. A cross-sectional study was conducted at King Salman Specialist Hospital from March to June 2024, enrolling 244 patients through convenience sampling. Data collection performed using following three validated questionnaires: Cardiac Patient Learning Needs Inventory (CPLNI) assess learning Health Questionnaire-9 (PHQ-9) evaluate depression levels, Oslo Social Support Scale (OSSS-3) measure support. Statistical analysis carried out IBM SPSS Statistics, Version 27. Patients aged 40 years or older those who were employed exhibited greater (p < 0.001). Female more depressed than males = 0.008). Higher reported by female with family history MI, 0.002, 0.003, respectively). The total mean score 3.72, highest in "other pertinent information", "medication "anatomy physiology". Depression indicated 45.1% significantly higher male Additionally, significant positive correlation found (r 0.205, p 0.001), negative -0.441, Addressing both physical psychological essential Comprehensive educational programs mental services necessary Personalized patient education routine screenings should be integrated into post-MI care. Future research examine longitudinal changes status.

Language: Английский

Citations

2
Depression in Cardiac Patients Is a Major Cardiovascular Event Risk Factor: A 12-Month Observational Study DOI Open Access
Jakub Podolec, Paweł Kleczyński, Marcin Piechocki

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(22), P. 6911 - 6911

Published: Nov. 16, 2024

: Depression is a known factor in poor cardiovascular outcomes but often underassessed cardiac units. This study evaluates the impact of depression on patients undergoing interventions.

Language: Английский

Citations

1
Primary Patency Success of Arteriovenous Shunts in Hemodialysis Patients: A 28-month Prospective Study at Al-Thawra Modern General Hospital, Yemen DOI

Nabeel Almadwahi,

Zaid Al-Dailami,

Gehad AL-Mashramah

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 17, 2024

Abstract Background: Arteriovenous (AV) shunts are vital for providing long-term vascular access in hemodialysis patients. While brachiocephalic and radiocephalic commonly employed, data on their primary patency rates associated complications resource-limited settings such as Yemen remain scarce. This study aimed to evaluate the success of AV identify factors influencing outcomes patients at Al-Thawra Modern General Hospital.Methods: prospective observational was conducted over 28 months, from April 2021 August 2023, Hospital Sana’a, Yemen. A total 163 with chronic renal failure requiring shunt creation were included. Data patient demographics, comorbidities, characteristics, postoperative collected. Primary assessed 8-month follow-up. Statistical analysis performed patency.Results: Among included, median age 43.12 years, 61.3% undergoing creation. The overall rate 8 months 87.7%, exhibiting a significantly greater (93.0%) than (67.3%) (p = 0.02). Complications occurred 25% patients, pseudoaneurysm formation being most common complication (6.1%). Factors type, age, comorbidities (e.g., diabetes) influence outcomes.Conclusion: Compared shunts, demonstrated superior rates, suggesting that they may be preferable options studied population. These findings emphasize need individualized management careful monitoring, particularly Yemen, optimize outcomes.

Language: Английский

Citations

0
Primary Patency Success of Arteriovenous Shunts in Hemodialysis Patients: A 28-Month Prospective Study DOI Open Access

Nabil Al Madhwahi,

Zaid Al-Dailami,

Gehad AL-Mashramah

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 25, 2024

Background Arteriovenous (AV) shunts are vital for providing long-term vascular access in hemodialysis patients. While brachiocephalic and radiocephalic commonly employed, data on their primary patency rates associated complications resource-limited settings such as Yemen remain scarce. This study aimed to evaluate the success of AV identify factors influencing outcomes patients at Al-Thawra Modern General Hospital. Methods prospective observational was conducted over 28 months, from April 2021 August 2023, Hospital Sana'a, Yemen. A total 163 with chronic renal failure requiring shunt creation were included. Data patient demographics, comorbidities, characteristics, postoperative collected. Primary assessed 8-month follow-up interval. Statistical analysis performed patency. Results Among enrolled patients, median age 43.12 years, 61.3% undergoing creation. The overall rate 8 months 87.7%, exhibiting a significantly greater (93.0%) than (67.3%) (p = 0.02). Complications occurred 25% pseudoaneurysm formation being most common complication (6.1%). Factors type, age, comorbidities (e.g., diabetes) influence outcomes. Conclusion Compared shunts, demonstrated superior rates, suggesting that they may be preferable option studied population. These findings emphasize need individualized management careful monitoring, particularly Yemen, optimize

Language: Английский

Citations

0
Prevalence of Depression and Its Associated Factors among Hemodialysis Patients in Hodeida City, Yemen [Response to Letter] DOI Creative Commons
Sameer A. Alkubati, Khaled Mohammed Al‐Sayaghi, Basma Salameh

et al.

Journal of Multidisciplinary Healthcare, Journal Year: 2024, Volume and Issue: Volume 17, P. 1177 - 1178

Published: March 1, 2024

Language: Английский

Citations

0
Anxiety and Depression Associated with Social Inequity Indicators in Patients with End-Stage Renal Disease: A Cross-Sectional Study in Tacna, Peru DOI Creative Commons
César Copaja-Corzo, Guimel Palomino-Guerra,

Dana Machaca-Choque

et al.

Clinical Epidemiology and Global Health, Journal Year: 2024, Volume and Issue: unknown, P. 101853 - 101853

Published: Nov. 1, 2024

Language: Английский

Citations

0
Mediating Role of Psychological Resilience Between Depression and Quality of Life in Maintenance Hemodialysis Patients in Baoding City, China: A Cross-Sectional Study DOI Creative Commons
Na Li

International Journal of General Medicine, Journal Year: 2024, Volume and Issue: Volume 17, P. 5929 - 5939

Published: Dec. 1, 2024

Patients with end-stage renal disease (ESRD) are at an increased risk for emotional issues, depression being the most prevalent psychological concern, significantly impacting their quality of life. This study aimed to explore mediating effect resilience on relationship between and life in maintenance hemodialysis (MHD) patients.

Language: Английский

Citations

0