Patient characteristics in relation to opioid exposure in a chronic non-cancer pain population DOI Creative Commons
Henrik Grelz, Ulf Jakobsson, Patrik Midlöv

et al.

Scandinavian Journal of Pain, Journal Year: 2024, Volume and Issue: 24(1)

Published: Jan. 1, 2024

Abstract Objectives The efficacy of long-term opioid therapy (LTOT) in treating patients with chronic non-cancer pain (CnCP) is questionable, and the potential risks adverse effects are well established. aims were as follows: (1) compare characteristics exposed to LTOT vs non-exposed. (2) Regarding opioid-exposed patients, describe risk factors for use disorder or overdose relation dosage. Method A cross-sectional study was conducted at a Swedish tertiary rehabilitation clinic serving CnCP patients. population comprised 1,604 ≥18 years old registered Quality Registry Pain Rehabilitation between 2018 2020. Data on dispensed opioids extracted from Prescribed Drug Register. Dependent variables non-LTOT dosage <50 mg morphine equivalent/day (MME/day) ≥50 MME/day. Results Of included 681 (42.5%) had least one dispensation 180 days prior assessment, 601 calculated ≥1 MME/day, 424 (26.4%) LTOT. type prescribed was, descending order, oxycodone (42.3% all dispensations), codeine combination paracetamol (17.6%), tramadol (13.8%), (8.1%). total 89 cases dosages MME/day 430 patient Patients exhibited an increased odds ratio (OR) 2.685 (95% CI, 1.942–3.711) concomitant benzodiazepines male sex (OR, 1.694; 95% 1.227–2.337). receiving doses all, except one, (OR 1.814, CI 1.264–3.331) 1.777; 1.178–3.102) indicated higher OR Conclusions strongly influenced dose. Furthermore, benzodiazepine over-represented those

Language: Английский

Rehabilitation interventions for neuropathic pain: a systematic review and meta-analysis of randomized controlled trials DOI Creative Commons
Emmanuel Bäckryd, Nazdar Ghafouri, Björn Gerdle

et al.

Journal of Rehabilitation Medicine, Journal Year: 2024, Volume and Issue: 56, P. jrm40188 - jrm40188

Published: Aug. 5, 2024

Rehabilitation interventions for chronic pain typically include education, cognitive behavioural therapy, and exercise or a combination of these. A systematic review meta-analysis rehabilitation neuropathic was conducted.

Language: Английский

Citations

2
Patient characteristics in relation to opioid exposure in a chronic non-cancer pain population DOI Creative Commons
Henrik Grelz, Ulf Jakobsson, Patrik Midlöv

et al.

Scandinavian Journal of Pain, Journal Year: 2024, Volume and Issue: 24(1)

Published: Jan. 1, 2024

Abstract Objectives The efficacy of long-term opioid therapy (LTOT) in treating patients with chronic non-cancer pain (CnCP) is questionable, and the potential risks adverse effects are well established. aims were as follows: (1) compare characteristics exposed to LTOT vs non-exposed. (2) Regarding opioid-exposed patients, describe risk factors for use disorder or overdose relation dosage. Method A cross-sectional study was conducted at a Swedish tertiary rehabilitation clinic serving CnCP patients. population comprised 1,604 ≥18 years old registered Quality Registry Pain Rehabilitation between 2018 2020. Data on dispensed opioids extracted from Prescribed Drug Register. Dependent variables non-LTOT dosage <50 mg morphine equivalent/day (MME/day) ≥50 MME/day. Results Of included 681 (42.5%) had least one dispensation 180 days prior assessment, 601 calculated ≥1 MME/day, 424 (26.4%) LTOT. type prescribed was, descending order, oxycodone (42.3% all dispensations), codeine combination paracetamol (17.6%), tramadol (13.8%), (8.1%). total 89 cases dosages MME/day 430 patient Patients exhibited an increased odds ratio (OR) 2.685 (95% CI, 1.942–3.711) concomitant benzodiazepines male sex (OR, 1.694; 95% 1.227–2.337). receiving doses all, except one, (OR 1.814, CI 1.264–3.331) 1.777; 1.178–3.102) indicated higher OR Conclusions strongly influenced dose. Furthermore, benzodiazepine over-represented those

Language: Английский

Citations

0