Sleep Duration, Sleep Habits, and Social Jetlag From 4 to 6 years Their Impacts on Myopia Among School-Aged Children: The Ma’anshan Birth Cohort Study

Nature and Science of Sleep, Journal Year: 2025, Volume and Issue: Volume 17, P. 365 - 378

Published: Feb. 28, 2025

To examine the associations of sleep parameters and their trajectories at preschool age with myopia among school-aged children by using a birth cohort study design. All participants were recruited from Ma'anshan Birth Cohort Study. Sleep duration, habits, social jetlag collected in 4 years, 5.5 6 years. Cycloplegic refraction ocular biometry performed 7 Key statistical analyses latent class growth models, binary logistic regression, generalized linear mixed respectively. A total 1561 included (mean 7.93 52.6% boys). Social least 1 hour was positively linked to an increased risk school-age axial length (AL) but negatively correlated spherical equivalent (SER) (P<0.05). Inadequate duration years associated increase AL (β=0.16; 95% CI: 0.07-0.24). pattern increasing-declining AL/CR ratio (RR=1.55; 95%CI: 1.01-2.37). Poor higher 4, declining-increasing trajectory SER Furthermore, elongation AL. The correlations between reveal that maintaining regular habits may contribute early prevention myopia.

Language: Английский

Relationship Between Poor Visual Acuity and Lifestyle: A Longitudinal and Cross-Sectional Study of Japanese Students Using Secondary Data

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: March 3, 2025

Background The incidence of myopia-related vision loss among Japanese children is increasing, indicating that efforts to prevent this remain insufficient. School-aged are thought be more prone myopia due physical and lifestyle changes during their growth stages. This study aimed clarify the relationship between in visual acuity (VA) from fourth-grade elementary school junior high students' habits examine maintain students Japan. Methods participants analysis included 49 students. Secondary data used were results tests questionnaires administered at schools. A longitudinal was performed by comparing conditions two time points: fourth grade school. Furthermore, examined. Results Poor significantly associated with poor (p=0.003). Students (PV) had a higher percentage following characteristics compared those without vision: studying for than hours per day on days off (p=0.043), spending less one hour computer weekdays (p=0.020), perceiving insufficient sleep duration (p=0.018), not paying attention taking breaks while or watching TV (p=0.038). Conclusion indicated school-aged may progressively worsen improvement. group spent weekends week, reported time, neglected TV. As grow, they tend spend changing living environment demands overuse eyes, increasing strain them. It necessary teach starting age eyesight still good.

Language: Английский

Diurnal gene expression patterns in retina and choroid distinguish myopia progression from myopia onset

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(7), P. e0307091 - e0307091

Published: July 19, 2024

The world-wide prevalence of myopia (nearsightedness) is increasing, but its pathogenesis incompletely understood. Among many putative mechanisms, laboratory and clinical findings have implicated circadian biology in the etiology myopia. Consistent with a hypothesis, we recently reported marked variability diurnal patterns gene expression two crucial tissues controlling post-natal refractive development ‐ retina choroid–at onset form-deprivation chick, widely studied validated model. To extend these observations, assayed by RNA-Seq choroid during progression established unilateral chick. We every 4 hours single day from myopic contralateral control eyes. Retinal choroidal vs. eyes differed strikingly at discrete times day. Very few differentially expressed genes occurred more than one time either tissue progressing Similarly, Gene Set Enrichment Analysis pathways varied markedly Some coincided candidate for human myopia, only partially corresponded previously identified onset. Considering other genetics epidemiology, results further link to myopia; they also point important mechanistic differences between Future investigations should systematically incorporate mechanisms studying seeking effective treatments normalize eye growth children.

Language: Английский