UPLC-MS metabolite profiling and antioxidant activity of Sanghuangporus sanghuang extract
PeerJ,
Journal Year:
2025,
Volume and Issue:
13, P. e18758 - e18758
Published: Jan. 22, 2025
Background
The
objective
of
the
present
study
is
to
examine
total
phenolic
and
flavonoid
content
an
ethanol
extract
Sanghuangporus
sanghuang
evaluate
its
phytochemical
properties,
antioxidant
activity,
capacity
protect
DNA
from
damage.
This
pharmaceutical/food
resource
mushroom
may
serve
as
a
novel
substitute
functional
food
for
health-conscious
consumers,
given
promising
source
phenolics
flavonoids.
Methods
S.
(SEE)
was
evaluated
contents,
while
UPLC-MS
analysis
used
terpenoids,
phenylpropanoid,
flavonoids,
steroidal,
phenols
identification,
function
prediction.
Antioxidant
anti-DNA
damage
activities
were
tested
in
vitro
using
ferric
reducing
power
(FRAP),
1,1-diphenyl-2-picrylhydrazyl
(DPPH),
2,2′-azino-bis-3-ethylbenzotiazolin-6-sulfonic
acid
(ABTS),
protection
assay.
Results
Conclusion
Total
(TPC)
SEE
385.38
±
1.36
mg
GA/g
extract,
(TFC)
298.22
2.38
QE/g
extract.
extracts
exhibited
high
free
radical
scavenging
with
relatively
stronger
activity.
A
491
metabolites
investigated
by
Ultra-performance
liquid
chromatography-mass
spectrometry
(UPLC-MS).
Most
top
20
compounds
predicted
have
various
functions
like
antioxidant,
anti-cancer
anti-inflammatory.
highlighted
beneficial
It
contains
potential
natural
that
could
be
lead
contender
development
medicines
treatment
wide
range
oxidative
stress-related
illnesses.
Language: Английский
Phytochemical characterization, antioxidant and antimicrobial activity of Erigeron bonariensis L.: A therapeutic weed
International Journal of Secondary Metabolite,
Journal Year:
2025,
Volume and Issue:
12(1), P. 188 - 203
Published: Jan. 19, 2025
Erigeron
bonariensis
L.
is
a
weed
belonging
to
the
Asteraceae
family
and
possesses
diverse
medicinal
properties.
It
known
have
therapeutic
uses,
including
infection
management
disease
treatment.
The
current
research
aims
investigate
pharmacological
phytochemical
properties
of
plant
extracts
(leaves
shoots).
A
thorough
examination
phytochemicals
was
carried
out
through
standardized
procedures,
quantitative
assessment
evaluated
spectral
analysis.
extract
subjected
investigation,
conclusively
establishing
its
potent
antioxidant
antimicrobial
activities.
activity
using
DPPH
(2,
2-diphenyl
1-picryl-hydrazyl)
scavenging
assay
NOSA
(Nitric
Oxide
scavenging)
assay,
while
determined
disc
diffusion
method.
screening
disclosed
presence
alkaloids,
sterols,
flavonoids,
tannins,
proteins,
fixed
oils
fats,
carbohydrates,
phenols,
glycosides,
saponins.
revealed
that
had
significant
capacity.
methanolic
leaf
exhibited
higher
efficacy
against
specific
varieties
Gram-negative
bacteria
(Escherichia
coli)
Gram-positive
(Bacillus
subtilis)
few
fungal
species
(Aspergillus
niger
Fusarium
oxysporum)
in
contrast
obtained
from
shoot,
as
evidenced
by
tests
conducted.
outcomes
indicate
leaves
bonariensis,
when
prepared
methanol,
show
greater
activities
than
shoots
do.
would
be
highly
beneficial
isolate
bioactive
compounds
responsible
for
natural
substances'
This
approach
can
facilitate
development
effective
treatments
various
health
conditions
future.
Language: Английский
Some biological activities of Thalictrum minus (Ranunculaceae)
International Journal of Secondary Metabolite,
Journal Year:
2025,
Volume and Issue:
12(1), P. 46 - 53
Published: Jan. 19, 2025
Plants
are
vital
natural
resources
that
used
in
a
wide
range
of
applications.
Throughout
history,
these
tools
have
proven
to
be
valuable
assets
for
individuals.
We
conducted
study
assess
the
biological
activity
aerial
portions
Thalictrum
minus
L.
In
this
particular
situation,
plant's
ethanol
and
methanol
extracts
were
obtained
using
Soxhlet
equipment.
The
Rel
Assay
kits
measure
total
antioxidant
status
(TAS),
oxidant
(TOS),
oxidative
stress
index
(OSI).
antiproliferative
effectiveness
against
A549
lung
cancer
cell
line
was
assessed
MTT
test.
anticholinesterase
by
measuring
activities
acetylcholinesterase
butyrylcholinesterase.
analyzed,
their
TAS
values
determined
4.371±0.083
4.027±0.081,
respectively.
TOS
11.816±0.121
13.580±0.176,
respectively,
whereas
OSI
0.271±0.007
0.337±0.009.
extract
plant
found
greater
than
extract.
had
an
anti-AChE
value
58.90±1.41,
while
65.11±1.01.
Similarly,
anti-BChE
72.25±0.79,
85.79±0.68.
Consequently,
it
established
has
antioxidant,
anticancer,
properties.
Language: Английский
Elaeagnus angustifolia L.: A Comprehensive Review of Its Biological Activities, Phenolic and Chemical Constituents, and Applications
Deleted Journal,
Journal Year:
2025,
Volume and Issue:
67(2)
Published: March 11, 2025
Language: Английский
An examination of the antioxidant and antibacterial capabilities, as well as the phenolic compounds, of Silene macrodonta and Silene chaetodonta
Hayrunnisa Elbozan,
No information about this author
Nuh Korkmaz
No information about this author
Prospects in Pharmaceutical Sciences,
Journal Year:
2025,
Volume and Issue:
23(2), P. 35 - 41
Published: April 29, 2025
In
this
study,
Silene
macrodonta
Boiss.
and
S.
chaetodonta
plant
species
belonging
to
the
Caryophyllaceae
family
growing
in
Gaziantep
region
were
examined
terms
of
antioxidant,
antimicrobial
phenolic
compounds.
Total
antioxidant
status
(TAS),
total
oxidant
(TOS)
oxidative
stress
index
(OSI)
values
determined
using
Rel
Assay
kits.
It
was
that
TAS
value
higher
with
5.983±0.156,
TOS
15.686±0.188,
OSI
0.341±0.010.
Within
scope
activity
by
Agar
dilution
method,
it
showed
than
macrodonta.
Phenolic
contents
plants
LC-MS/MS
device.
For
some
standards
used,
presence
compounds
detected.
As
a
result
studies,
have
high
biological
activity.
Language: Английский
Evaluation of The Antimicrobial, Antioxidant, and Other Biological Activities of Tribulus terrestris Plants Collected From Different Countries
Egyptian Journal of Veterinary Science,
Journal Year:
2024,
Volume and Issue:
0(0), P. 0 - 0
Published: July 22, 2024
The
present
investigation
aimed
to
assess
the
antibacterial,
antioxidant,
anticholinesterase,
and
antiproliferative
properties
of
Tribulus
terrestris
L.
samples
obtained
from
Iraq
Turkey.
Furthermore,
total
contents
flavonoids
phenols
were
ascertained.
above-ground
parts
plant
extracted
with
ethanol
Total
antioxidant
status
(TAS),
oxidant
(TOS)
as
well
oxidative
stress
index
(OSI)
determined.
Antimicrobial
activity
against
Staphylococcus
aureus,
Enterococcus
faecalis,
Escherichia
coli,
Pseudomonas
aeruginosa,
Acinetobacter
baumannii,
Candida
albicans,
C.
krusei
glabrata
was
assessed.
Also,
tested
lung
cancer
cell
line.
results
showed
that
extracts
effective
microorganisms
at
50-200
µg/mL
concentrations.
TAS
values
collected
Türkiye
determined
7.703±0.246
mmol/L
6.992±0.216
mmol/L,
TOS
15.983±0.477
μmol/L
10.595±0.253
μmol/L,
OSI
0.207±0.001
0.152±0.005,
respectively.
In
addition,
anti-AChE
51.99±1.78
μg/mL
74.24±2.35
μg/mL,
anti-BChE
40.85±2.66
64.43±2.58
Plant
strong
effects
A549
line
in
a
concentration-dependent
manner.
phenolic
be
90.10±3.66
mg/g
78.24±1.51
mg/g,
flavonoid
112.17±3.12
119.50±2.52
It
can
concluded
T.
plants
have
biological
activities
enable
them
applied
food
or
feed
additives
pharmaceutical
supplements.
Language: Английский
Antioxidant, Antimicrobial and Antialzeihmer activities of Tagetes patula (Asteraceae)
Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 23, 2024
Plants
are
natural
products
used
in
the
prevention
and
treatment
of
many
diseases.
In
this
study,
antioxidant,
antimicrobial,
anticholinesterase
activities
total
phenolic
flavonoid
contents
Tagetes
patula
L.
samples
collected
from
Iraq
were
determined.
The
aerial
parts
plant
extracted
with
ethanol
a
soxhlet
device.
antioxidant
potential
extracts
was
measured
Rel
Assay
kits.
Antimicrobial
activity
determined
by
agar
dilution
method
against
standard
bacterial
fungal
strains.
To
determine
acetyl
butyrylcholinesterase
inhibitions
tested.
content
carried
out
using
Folin-Ciocalteu
reagent.
quantification
flavonoids
conducted
an
aluminum
chloride
assay.
As
result
analyses,
value
extract
as
5.386±0.142
mmol
Trolox
equiv./L,
oxidant
8.287±0.146
μmol
H2O2
equiv./L
oxidative
stress
index
0.154±0.003.
Plant
showed
highest
Candida
species.
It
also
effective
strains
at
concentrations
between
50-400
µg/mL.
Acetylcholinesterase
24.97±0.98,
35.65±0.94.
Additionally,
its
63.64±0.74
mgGAE/g
108.9±1.55
mgQE/g.
has
been
that
antiallergic
potential.
Language: Английский
General properties, biosynthesis, pharmacological properties, biological activities and daily uses of luteolin
Prospects in Pharmaceutical Sciences,
Journal Year:
2024,
Volume and Issue:
22(4), P. 146 - 154
Published: Dec. 27, 2024
Phenolic
molecules
are
secondary
metabolites
that
facilitate
several
biological
processes.
Secondary
non-nutritive
substances
hold
significant
medicinal
value.
Our
study
combined
the
activities,
general
features,
daily
usage
conditions,
and
biosynthesis
of
luteolin
as
reported
in
literature.
The
literature
review
revealed
exhibits
activities
including
antioxidant,
antibacterial,
anticancer,
anti-inflammatory
properties.
It
was
observed
it
exerts
effects
on
illnesses
cardioprotection,
cholesterol
regulation,
neuroprotection,
autistic
spectrum
disorders,
gastrointestinal
issues,
obesity,
insulin
sensitivity,
anxiety/depression,
arthritis.
In
this
regard,
identified
a
molecule
for
pharmacological
applications.
Language: Английский
Citrullus colocynthis (Bitter-apple): a comprehensive review on general properties, biological activities, phenolic and chemical contents
Notulae Scientia Biologicae,
Journal Year:
2024,
Volume and Issue:
16(4), P. 12202 - 12202
Published: Dec. 19, 2024
Plants
display
several
biological
activities
as
a
result
of
the
production
various
chemicals
inside
their
metabolic
processes.
In
recent
times,
growing
prevalence
alternative
medicine
uses
has
elevated
significance
plants.
The
present
work
aimed
to
assess
activities,
phenolic
and
chemical
compositions,
applicability,
mineral
composition,
overall
characteristics
Citrullus
colocynthis
(L.)
Schrad.
documented
in
existing
literature.
Literature
study
revealed
that
it
possesses
significant
antioxidant,
antibacterial,
anticancer
properties.
Furthermore,
been
observed
may
serve
potential
reservoir
for
minerals
its
structure.
It
is
also
thought
be
an
important
source,
especially
terms
potassium.
From
this
perspective,
became
evident
fruit
components
plant,
particular,
could
natural
resource
promoting
health.
Language: Английский