medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 22, 2024
Abstract
Bimodal
neuromodulation
combining
sound
therapy
with
electrical
tongue
stimulation
using
the
Lenire
device
is
emerging
as
an
effective
treatment
for
tinnitus.
A
single-arm
retrospective
chart
review
analyzes
real-world
outcomes
220
tinnitus
patients
from
Alaska
Hearing
and
Tinnitus
Center
recently
FDA-approved
first
time
in
a
United
States
clinic.
The
primary
endpoint
examines
responder
rate
mean
change
Handicap
Inventory
(THI)
after
approximately
12
weeks
of
eligible
moderate
or
worse
represents
THI
improvement
greater
than
seven
points
(i.e.,
minimal
clinically
important
difference,
MCID).
Of
212
available
data,
there
was
high
91.5%
(95%
CI:
86.9%,
94.5%)
27.8
±
1.3
(SEM)
points,
no
device-related
serious
adverse
events.
Furthermore,
MCID
consistent
criterion
clinical
benefit
based
on
evidence.
Frontiers in Audiology and Otology,
Journal Year:
2024,
Volume and Issue:
1
Published: Jan. 9, 2024
Background
While
there
is
no
cure
for
tinnitus,
research
has
shown
that
cognitive
behavioral
therapy
(CBT)
effective
in
managing
clinical
sequelae.
Although
traditional
CBT
labor-intensive
and
costly,
new
online
consultations
may
improve
accessibility.
Moreover,
promise
an
engaging
conversational
agent,
or
a
“chatbot,”
delivering
conversation-like
manner
allowing
users
to
work
through
complex
situations
with
the
guidance
of
virtual
coach.
Currently,
little
examining
possible
hybrid
model
using
iCBT
tele
consultation
psychologist.
Methods
A
randomized,
2
parallel-group
trial
was
conducted
compare
effectiveness
(1)
delivered
chatbot
mobile
app
(i.e.,
Tinnibot
only
group)
(2)
combined
telepsychology
hybrid-intervention
group).
total
30
eligible
adults
tinnitus
were
included.
After
8-week
intervention
period,
participants
followed
up
months.
The
primary
outcome
measure,
Tinnitus
Functional
Index
(TFI),
secondary
measures,
Hyperacusis
Questionnaire
(HQ),
Generalized
Anxiety
Disorder
7-item
(GAD-7),
Patient
Health
(PHQ-9),
assessed
before
treatment,
post-treatment,
at
follow-up.
Results
TFI
decreased
significantly
over
time
both
groups,
trend
larger
improvement
group
received
telepsychology.
At
clinically
significant
observed
42%
Tinnibot-only
64%
group.
follow-up,
this
groups.
PHQ-9
GAD-7
improved
time,
but
HQ
did
not.
Discussion
Internet-based
delivery
decreasing
distress,
levels
anxiety
depression,
which
more
relevant
today
than
ever
context
global
pandemic
challenged
face-to-face
intervention.
addition
might
be
beneficial,
not
essential
treatment.
There
need
further
determine
whether
any
relationship
between
characteristics
patients
success
different
modes
therapy.
Journal of the Association for Research in Otolaryngology,
Journal Year:
2024,
Volume and Issue:
25(5), P. 413 - 425
Published: Aug. 13, 2024
Tinnitus,
the
perception
of
sound
without
an
external
source,
affects
15%
population,
with
2.4%
experiencing
significant
distress.
In
this
review,
we
summarize
current
state
knowledge
about
tinnitus
management
a
particular
focus
on
translation
into
clinical
practice.
first
section,
analyze
shortcomings,
gaps,
and
challenges
in
field
research.
Then,
highlight
relevance
diagnostic
process
to
account
for
heterogeneity
identify
all
relevant
aspects
individual
patient,
such
as
etiological
aspects,
pathophysiological
mechanisms,
factors
that
contribute
most
suffering,
comorbidities.
next
review
available
treatment
options,
including
counselling,
cognitive-behavioral
therapy
(CBT),
hearing
aids
cochlear
implants
patients
loss,
generators,
novel
auditory
stimulation
approaches,
retraining
(TRT),
pharmacological
treatment,
neurofeedback,
brain
stimulation,
bimodal
Internet-
app-based
digital
alternative
approaches.
The
evidence
effectiveness
various
interventions
varies
considerably.
We
also
discuss
differences
respective
guideline
recommendations
close
discussion
how
knowledge,
latest
scientific
evidence,
patient
perspectives
can
be
translated
patient-centered
care.
Journal of Clinical Medicine,
Journal Year:
2025,
Volume and Issue:
14(4), P. 1166 - 1166
Published: Feb. 11, 2025
Background:
Tinnitus
can
significantly
impact
a
patient's
quality
of
life.
As
no
evidence-based
curative
treatments
exist,
therapies
such
as
cognitive
behavioral
therapy,
tinnitus
retraining
acceptance
and
commitment
mindfulness-based
interventions
aim
to
minimize
severity
have
been
shown
effective.
Since
traditional
delivery
be
costly
time-consuming
often
has
limited
accessibility,
might
also
provided
via
eHealth.
This
study
investigates
the
change
in
measured
by
Functional
Index
(TFI)
score
after
participation
an
online
self-paced
("Still
Tinnitus")
course.
The
secondary
was
identify
predictors
for
clinically
relevant
improvement
this
Methods:
retrospective
record
included
patients
from
Still
course
between
March
2023
July
2024.
Patients
were
recruited
website.
Differences
TFI
scores
baseline
completing
fifth
(last)
module
calculated
investigate
over
time.
Multivariate
logistic
analyses
performed
possible
completion
Results:
In
total,
122
study.
analysis
revealed
reduction
27.2
points.
Multiple
regression
showed
that
"duration
tinnitus"
(OR
5.0;
95%CI:
1.537-16.240;
p
=
0.007)
"female
sex"
1.9;
95%CI
0.111-7.637;
0.030)
are
improvement.
Conclusions:
convenience
sample
patients,
may
contribute
severity.
A
shorter
duration
female
sex
identified
significant
predictors.
Seminars in Hearing,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 21, 2025
Abstract
This
article
is
the
second
in
a
two-part
series
intended
to
provide
guidance
related
essential
components
of
establishing
comprehensive
tinnitus
care
pathway
your
clinic.
Please
see
“Part
1:
Essential
Components”
for
relevant
background
information
detailing
why
each
described
this
were
included.
BMC Psychology,
Journal Year:
2025,
Volume and Issue:
13(1)
Published: March 26, 2025
The
aim
of
this
study
was
to
evaluate
the
use
applications
accessed
through
internet
browsers
as
tools
for
neuropsychiatric
treatment,
well
verify
benefits
and
efficacy
virtual
support
a
therapeutic
approach.
A
broad
review
MEDLINE
(PubMed),
SciELE
Cochrane
databases
articles
conducted.
Articles
involving
browser-based
neurological
psychiatric
with
available
texts
on
selected
platforms
no
language
or
year
restrictions,
were
included.
total
83
reviews
included
in
study.
Due
homogeneity
information
between
some
articles,
research
grouped
according
following
revised
themes:
mindfulness,
tinnitus,
electronic
health
(eHealth),
youth
students'
mental
health,
mobile
(mHealth),
depression,
anxiety
stress,
psychoactive
substances,
sleep
quality,
chronic
diseases
disorders.
findings
suggest
that
helps
improving
well-being
quality
life
these
patients.
Communications Medicine,
Journal Year:
2025,
Volume and Issue:
5(1)
Published: April 28, 2025
Abstract
Background
Bimodal
neuromodulation
combining
sound
therapy
with
electrical
tongue
stimulation
using
the
Lenire®
device
is
emerging
as
an
effective
treatment
for
tinnitus.
Methods
A
single-arm
retrospective
chart
review
of
220
patients
tinnitus
from
Alaska
Hearing
&
Tinnitus
Center
examines
real-world
outcomes
recently
FDA-approved
Lenire
treatment.
To
best
our
knowledge,
this
first
assessment
a
clinic
in
United
States.
The
primary
endpoint
responder
rate
and
mean
change
Handicap
Inventory
(THI)
after
~12
weeks
eligible
moderate
or
worse
represents
THI
improvement
greater
than
seven
points
(i.e.,
minimal
clinically
important
difference,
MCID).
Results
Here
we
show
that,
out
212
available
data,
there
was
high
91.5%
(95%
CI:
86.9%,
94.5%)
27.8
±
1.3
(SEM)
points,
no
device-related
serious
adverse
events.
Furthermore,
MCID
consistent
criterion
clinical
benefit
based
on
evidence
practice
settings.
Conclusions
These
findings
that
can
be
used
to
safely
effectively
reduce
setting.
Frontiers in Neuroscience,
Journal Year:
2025,
Volume and Issue:
19
Published: May 9, 2025
Background
Tinnitus,
defined
as
the
perception
of
sound
without
an
external
auditory
stimulus,
affects
millions
worldwide,
significantly
diminishing
their
quality
life.
Cognitive
behavioral
therapy
(CBT)
is
most
evidence-based
treatment
for
tinnitus
management,
proven
effective
in
reducing
tinnitus-related
distress
and
severity.
This
study
aims
to
evaluate
current
status,
emerging
trends,
research
hotspots
CBT
using
bibliometric
methods,
offering
valuable
insights
future
studies
this
field.
Methods
Publications
related
were
retrieved
from
Web
Science
Core
Collection
(WoSCC)
database
1985
2024.
Bibliometric
analysis
visualization
performed
VOSviewer,
CiteSpace,
R
package
“bibliometrix.”
Results
A
total
209
publications
included
study.
Research
on
has
shown
a
steady
upward
trend.
Sweden,
United
Kingdom
States
have
made
notable
contributions
Linköping
University
Karolinska
Institute
are
leading
institutions.
Gerhard
Andersson
prolific
author
ranks
first
citation
frequency.
The
journal
American
Journal
Audiology,
while
Ear
Hearing
frequently
co-cited
journal.
highly
cited
references
primarily
encompass
clinical
trials,
systematic
reviews,
meta-analyses
that
focus
cognitive-behavioral
interventions.
Recent
keyword
trends
highlight
topics
such
“mindfulness,”
“acceptance
commitment
therapy,”
“internet-based
interventions.”
Addressing
psychological
comorbidities
tinnitus,
including
depression
anxiety,
identified
focus.
Conclusion
provides
comprehensive
overview
landscape
management.
Current
emphasizes
various
modalities
treat
associated
with
tinnitus.
Future
should
prioritize
high-quality
confirm
long-term
efficacy
Telemedicine Journal and e-Health,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 25, 2024
:
e-Health
or
web-based
systems
in
the
field
of
tinnitus
have
gained
increasing
interest.
Cognitive
behavioral
therapy
(CBT)
delivered
via
internet
is
currently
witnessing
a
surge
both
attention
and
offerings.
This
systematic
review
analyzed
efficacy
sustainability
internet-based
therapies
aimed
at
reducing
distress
comorbidities
such
as
anxiety,
depression,
sleep
disorders.
The
exclusively
considered
randomized
controlled
trials
(RCTs)
which
trained
personnel
were
actively
involved
during
intervention.
Telemedicine Journal and e-Health,
Journal Year:
2023,
Volume and Issue:
30(2), P. 307 - 320
Published: Aug. 11, 2023
The
use
of
telerehabilitation
for
the
treatment
speech
and
language
disorders
in
field
hearing
is
increasing.
A
comprehensive
study
comparing
telerehabilitation's
effectiveness
with
traditional
rehabilitation
can
help
us
understand
it
better.
Therefore,
this
systematic
review
aimed
to
compare
children
disabilities
2023.
Journal of Personalized Medicine,
Journal Year:
2024,
Volume and Issue:
14(8), P. 813 - 813
Published: July 31, 2024
Tinnitus
presents
a
major
public
health
challenge,
impacting
quality
of
life.
With
conventional
therapies
being
often
time-consuming
and
costly,
interest
in
Internet-based
treatments,
such
as
auditory
treatments
cognitive
behavioral
therapy,
has
grown
due
to
their
improved
patient
adherence.
This
meta-analysis
aims
review
existing
scientific
literature
assess
the
effectiveness
(IBTs)
treating
tinnitus.
