Factors influencing COVID-19 vaccine acceptability among household heads in northern Nigeria: a community-based cross-sectional study

BMJ Open, Journal Year: 2025, Volume and Issue: 15(1), P. e083470 - e083470

Published: Jan. 1, 2025

Objectives COVID-19 vaccine was rolled out for the public in August 2021 Zamfara state, Northen Nigeria. We determined factors influencing acceptance. Settings executed a community-based analytical cross-sectional study during first 4 months of second phase (Oxford/AstraZeneca) mass vaccination campaign state. Participants used multistage sampling to select 910 household heads. Outcome measures semistructured electronic questionnaire collect data on sociodemographic characteristics, uptake and acceptance between 12 October 20 December 2021. calculated frequencies, proportions, adjusted ORs 95% CIs using logistic regression. Results Our respondents had median age 48 years (IQR: 37–55), 78.1% (711) were men, majority more than 30 years, only 8.9% (81) received vaccine. Of 829 unvaccinated respondents, 10.1% (84) accepted take vaccine, current week interview while 12.2% (101) rejected Individuals aged older (adjusted OR (aOR)=2.39, CI 1.16 4.94, p=0.018), who owned mobile phone (aOR=25.35, 11.23 57.23, p<0.001) television (aOR=3.72, 1.09 12.69, p=0.036), with medium–high levels trust (aOR=7.41, 3.10 17.74, p<0.001), those (positive) attitude (aOR=1.82, 1.06 3.11, p=0.029) likely accept Also, been vaccinated other vaccines (aOR=2.2, 4.43, p=0.027) previously tested (aOR=2.0, 1.10 3.66, p=0.023) also it. Conclusion poor Factors such as age, awareness, previous experience played significant role recommended targeted health campaigns, improving community engagement building leaders, healthcare providers institutions.

Language: Английский

Cost-effectiveness of a behavioral insights-informed digital campaign to increase HPV vaccination in Bangladesh

Human Vaccines & Immunotherapeutics, Journal Year: 2025, Volume and Issue: 21(1)

Published: May 5, 2025

Digital platforms like social media are increasingly used to promote vaccine uptake in low- and middle-income countries (LMICs), yet limited evidence exists on their economic value. This study estimates the cost-effectiveness of a behavioral insights-informed campaign designed increase HPV among adolescent girls ages 9-14 Bangladesh. A static analysis was conducted from health system perspective. Inputs included delivery costs, procurement distribution, treatment costs averted through cervical cancer prevention. Disability-adjusted life years (DALYs) per vaccinated girl were modeled using global burden-of-disease parameters. Effectiveness drawn quasi-experimental evaluation campaign, which reported 9.5 percentage-point one arm 5.3 another, relative control group. These findings preceded by posttest Dhaka Division, showed strong association between exposure vaccination behavior. The incremental cost $6.02, DALY - i.e. Incremental Cost-Effectiveness Ratio (ICER) $39.57. falls well below established thresholds, including 40% GDP capita, commonly applied LMICs. suggest that digital campaigns guided insights can represent highly cost-effective approach addressing persistent immunization coverage gaps. results support integration such strategies into national programs, particularly contexts where traditional outreach methods may face financial constraints.

Language: Английский

Evaluating hepatitis B screening, prevalence, vaccination coverage, and linkage to care in Abuja, Nigeria: insights from a cross-sectional study

BMC Public Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: Dec. 18, 2024

Hepatitis B virus (HBV) is a major global health threat, especially in Sub-Saharan Africa, where Nigeria has prevalence exceeding 8%. Despite the availability of effective vaccines, inadequate coverage and lack awareness have resulted high rates chronic infections HBV-attributable liver disease. The study aimed to raise HBV, enroll participants for HBV screening, determine across various communities, vaccinate negative cases link positive care. A cross-sectional was conducted 16 districts Abuja from April 2022 March 2023. Participants aged 18 over were screened hepatitis B, those testing offered on-site vaccination. Blood samples collected tested using immunochromatographic tests real-time polymerase chain reaction (RT-PCR) DNA quantification. Data through interviews analyzed R software, with descriptive statistics calculated continuous categorical variables. Associations between socio-demographic factors B/vaccine status assessed Chi-square test independence. Out 3,245 individuals screened, 141 (4.3%) HBV. highest observed 20–39 age group (5.9%), males showing higher infection rate (5.4%) compared females (3.7%) [p = 0.02]. mean HBV-positive significantly lower (30.8 years) than (36.2 < 0.001]. Among 2,506 who consented vaccination, 2,488 received first dose (99.3%), 1,834 second (73.2%), 1,100 third (43.9%). Vaccination uptake declined each subsequent dose, but more older completed dose. similar pattern gender groups. reveals 4.3% among years, females. Although vaccination adherence doses. These findings highlight need targeted public interventions, particularly younger adults males, improve completion. Enhanced community engagement sustained efforts are crucial reducing transmission achieving better coverage.

Language: Английский