Journal of Medical Internet Research,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 28, 2024
Escalating
mental
health
demand
exceeds
existing
clinical
capacity,
requiring
scalable
digital
solutions.
However,
engagement
remains
challenging.
Conversational
agents
enhance
by
making
programs
more
interactive
and
personalized
but
have
not
been
widely
used.
This
study
evaluated
a
program
for
anxiety
against
external
comparators.
The
used
an
AI-driven
conversational
agent
to
deliver
clinician-written
content
via
machine
learning,
with
clinician
oversight
user
support.
aimed
evaluate
the
engagement,
effectiveness,
safety
of
this
structured,
evidence-based
human
support
mild,
moderate
severe
generalized
anxiety.
Statistical
analyses
determine
whether
reduced
than
propensity-matched
waiting
control
was
statistically
non-inferior
real-world
face-to-face
typed
cognitive
behavioral
therapy
(CBT).
Prospective
participants
(N=299)
were
recruited
from
NHS
or
social
media
in
UK
given
use
up
9
weeks
(study
conducted
October
2023
May
2024).
Endpoints
collected
before,
during
after
program,
at
one-month
follow-up.
External
comparator
groups
generated
through
propensity-matching
sample
Talking
Therapies
(NHS
TT)
data
ieso
Digital
Health
(typed-CBT)
Dorset
Healthcare
University
Foundation
Trust
(DHC)
(face-to-face
CBT).
Superiority
non-inferiority
compare
symptom
reduction
(change
on
GAD-7
scale)
group
groups.
included
time
spent
per
participant
calculated.
Participants
median
6
hours
over
53
days,
78%
(n=232)
engaged
(i.e.
completed
2
14
days).
There
large
clinically
meaningful
symptoms
(per-protocol
(PP;
n=169):
change
=
-7.4,
d
1.6;
intention-to-treat
(ITT;
n=299):
-5.4,
d=1.1).
PP
effect
superior
(d
1.3),
CBT
(p
<.001)
typed-CBT
<.001).
Similarly,
ITT
sample,
showed
superiority
(d=0.8)
(p=.002)
approaching
significance
(p=.06).
Effects
sustained
Clinicians
overseeing
mean
1.6
(31
-
200
minutes)
sessions
participant.
By
combining
AI
support,
achieved
outcomes
comparable
human-delivered
care
while
significantly
reducing
required
8
times
relative
global
estimates.
These
findings
highlight
potential
technology
scale
healthcare,
address
unmet
need,
ultimately
impact
quality
life
economic
burden
globally.
ISRCTN
id:
52546704.
Journal of Eating Disorders,
Journal Year:
2025,
Volume and Issue:
13(1)
Published: March 11, 2025
Abstract
Background
Early
treatment
is
critical
to
improve
eating
disorder
prognosis.
Single
session
interventions
have
been
proposed
as
a
strategy
provide
short
term
support
people
on
waitlists
for
treatment,
however,
it
not
always
possible
access
this
early
intervention.
Conversational
artificial
intelligence
agents
or
“chatbots”
reflect
unique
opportunity
attempt
fill
gap
in
service
provision.
The
aim
of
research
was
co-design
novel
chatbot
capable
delivering
single
intervention
adults
the
waitlist
across
diagnostic
spectrum
and
ascertain
its
preliminary
acceptability
feasibility.
Methods
A
Double
Diamond
approach
employed
which
included
four
phases:
discover,
define,
develop,
deliver.
There
were
17
participants
total
Australia;
ten
with
lived
experience
an
seven
registered
psychologists
working
field
disorders,
who
participated
online
interviews
workshops.
Thematic
content
analyses
undertaken
interview/workshop
transcriptions
findings
from
previous
phase
informing
ideas
development
next
phase.
final
prototype
presented
deliver
Results
identified
main
themes
that
present
phases
interviews/workshops:
conversational
tone,
safety
risk
management,
user
journey
structure,
content.
Conclusions
Overall,
feedback
positive
throughout
process
both
psychologists.
Incorporating
allowed
refinement
chatbot.
Further
required
evaluate
chatbot’s
efficacy
settings.
Family Relations,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 27, 2025
Abstract
Objective
We
aim
to
describe
the
development
of
a
conversational
agent
(CA)
for
parenting,
termed
PAT
(Parenting
Assistant
platform),
demonstrate
how
artificial
intelligence
(AI)
can
enhance
parenting
skills.
Background
Behavioral
problems
are
most
common
issues
in
childhood
mental
health.
Developing
and
disseminating
scalable
interventions
address
early‐stage
behavioral
high
priority.
Artificial
(AI)‐based
CAs
offer
innovative
methods
deliver
reduce
problems.
have
capability
interact
through
text
or
voice
conversations
undergo
training
using
evidence‐based
programs.
However,
research
on
is
limited.
Experience
The
consisted
three
phases:
Phase
1
was
purely
rule‐based,
2
hybrid
(rule‐based
format
plus
large
language
models),
3
featured
an
agentic
architecture.
latest
version
includes
prompt
engineering,
guardrails,
retrieval‐augmented
generation,
few‐shots
learning,
context,
memory
management
Although
comprehensive
empirical
results
pending,
iterative
enhancement
indicate
potential
effective
digital
intervention.
architecture
aims
provide
robust,
context‐aware
interactions
support
challenges.
Implications
reach
broader
population
parents
personalized
tailored
their
specific
needs.
Moreover,
structured
timely
support,
which
family
dynamics
contribute
improved
long‐term
outcomes
both
children.
Conclusion
AI‐based
be
used
as
alternatives
waitlists;
cotherapists;
implemented
health
care,
health,
school
settings.
benefits
risks
different
types
CA
features
discussed.
Translational Behavioral Medicine,
Journal Year:
2025,
Volume and Issue:
15(1)
Published: Jan. 1, 2025
Abstract
Background
Digital
health
(DH)
technologies
provide
scalable
and
cost-effective
solutions
to
improve
population
but
face
challenges
of
uneven
adoption
high
attrition,
particularly
among
vulnerable
minority
groups.
Purpose
This
study
explores
factors
influencing
DH
in
a
multicultural
identifies
strategies
equitable
access.
Methods
Using
Patient
Public
Involvement
approach,
lay
facilitators
engaged
adults
at
public
eateries
Singapore
discuss
motivations
barriers
adoption.
A
semi-structured
guide
facilitated
discussions,
followed
by
an
optional
socio-demographic
survey.
Data
were
analyzed
through
inductive
thematic
analysis
mapped
behavior
change
theory
identify
mechanisms
action
(MoA)
techniques
(BCTs)
support
Results
Facilitators
118
participants
between
November
2022
February
2023.
Five
key
themes
identified
from
the
discussions:
(a)
awareness
solutions,
(b)
weighing
benefits
against
burdens,
(c)
accessibility,
(d)
trust
developers
technology,
(e)
impact
user
experience.
These
13
MoA
26
BCTs,
informing
five
enhance
adoption:
community-based
promotion
credible
digital
literacy
training,
brief
counselling
opportune
moments
healthcare
settings,
variable
rewards
tied
personal
values,
policies
ensuring
accessibility
regulation,
gamified,
user-friendly
designs
emphasizing
feedback
behavioral
cues.
Conclusion
Designing
implementing
that
are
accessible,
trustworthy,
motivating—integrated
within
services
promoted
community
efforts—can
address
diverse
communities
may
help
narrow
divide.
International Journal of Law and Psychiatry,
Journal Year:
2025,
Volume and Issue:
101, P. 102105 - 102105
Published: May 3, 2025
The
current
and
potential
impact
of
various
applications
artificial
intelligence
(AI)
to
the
field
academic
publishing
in
psychiatry
is
subject
increasing
attention.
At
present,
AI
algorithms
assist
data
analysis,
allowing
researchers
process
large
datasets
quickly
uncover
complex
patterns
that
would
be
challenging
detect
manually.
In
psychiatry,
this
capability
can
potentially
help
integrate
from
genetics,
neuroimaging,
clinical
assessments.
AI-driven
natural
language
processing
(NLP)
tools
might
also
facilitate
systematic
reviews
meta-analyses
by
automating
extraction
synthesis
information
vast
bodies
published
literature.
publishing,
streamline
publication
certain
ways.
Automated
systems
screen
manuscripts
for
methodological
rigor,
ethical
compliance,
conflicts
interest,
thereby
reducing
burden
on
editors
prompting
them
consider
matters,
possibly
accelerating
timeline.
AI-powered
are
already
used
with
dissemination
research
findings
generating
summaries
identifying
key
insights,
making
more
accessible
a
broader
audience.
future,
has
enhance
psychiatric
other
Predictive
analytics
identify
emerging
trends
gaps
literature,
guiding
future
studies
funding
priorities,
although
remains
speculative
now.
could
robust
collaborations
connecting
complementary
expertise
interests.
Additionally,
integration
digital
platforms
democratise
access
cutting-edge
research,
promote
global
knowledge
sharing,
accelerate
advancements
care.
As
continues
evolve,
its
hold
drive
significant
progress
understanding
treating
mental
disorders.
It
essential
these
developments
accompanied
openness
about
use
clear
declarations
authors
publishers
specific
work.
Journal of Medical Internet Research,
Journal Year:
2024,
Volume and Issue:
26, P. e53327 - e53327
Published: March 26, 2024
Background
The
increased
pervasiveness
of
digital
health
technology
is
producing
large
amounts
person-generated
data
(PGHD).
These
can
empower
people
to
monitor
their
promote
prevention
and
management
disease.
Women
make
up
one
the
largest
groups
consumers
self-tracking
technology.
Objective
In
this
scoping
review,
we
aimed
(1)
identify
different
areas
women’s
monitored
using
PGHD
from
connected
devices,
(2)
explore
personal
metrics
collected
through
these
technologies,
(3)
synthesize
facilitators
barriers
adoption
use
devices.
Methods
Following
PRISMA
(Preferred
Reporting
Items
for
Systematic
Reviews
Meta-Analyses)
guidelines
reviews,
searched
5
databases
articles
published
between
January
1,
2015,
February
29,
2020.
Papers
were
included
if
they
targeted
women
or
female
individuals
incorporated
tools
that
outside
a
clinical
setting.
Results
We
total
406
papers
in
review.
Articles
on
steadily
2015
focused
spanned
several
topics,
with
pregnancy
postpartum
period
being
most
prevalent
followed
by
cancer.
Types
used
collect
mobile
apps,
wearables,
websites,
Internet
Things
smart
2-way
messaging,
interactive
voice
response,
implantable
A
thematic
analysis
41.4%
(168/406)
revealed
6
themes
regarding
collecting
PGHD:
accessibility
connectivity,
design
functionality,
accuracy
credibility,
(4)
audience
adoption,
(5)
impact
community
service,
(6)
behavior.
Conclusions
Leading
COVID-19
pandemic,
address
concerns
was
steady
rise.
prominence
related
reflects
strong
focus
reproductive
research
highlights
opportunities
development
other
topics.
Digital
acceptable
when
it
relevant
target
audience,
seen
as
user-friendly,
considered
personalization
preferences
while
also
ensuring
measurements
credibility
information.
integration
technologies
into
care
will
continue
evolve,
factors
such
liability
provider
workload
need
be
considered.
While
acknowledging
diversity
individual
needs,
positively
self-care
numerous
journeys.
pandemic
has
ushered
acceptance
This
study
could
serve
baseline
comparison
how
field
evolved
result.
International
Registered
Report
Identifier
(IRRID)
RR2-10.2196/26110
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: July 17, 2024
Abstract
Escalating
global
mental
health
demand
exceeds
existing
clinical
capacity.
Scalable
digital
solutions
will
be
essential
to
expand
access
high-quality
healthcare.
This
study
evaluated
the
effectiveness
of
a
intervention
alleviate
mild,
moderate
and
severe
symptoms
generalized
anxiety.
structured,
evidence-based
program
combined
an
Artificial
Intelligence
(AI)
driven
conversational
agent
deliver
content
with
human
oversight
user
support
maximize
engagement
effectiveness.
The
was
compared
three
propensity-matched
real-world
patient
comparator
groups:
i)
waiting
control;
ii)
face-to-face
cognitive
behavioral
therapy
(CBT);
iii)
remote
typed-CBT.
Endpoints
for
effectiveness,
engagement,
acceptability,
safety
were
collected
before,
during
after
intervention,
at
one-month
follow-up.
Participants
(n=299)
used
median
6
hours
over
53
days.
There
large
clinically
meaningful
reduction
in
anxiety
group
(per-protocol
(n=169):
change
on
GAD-7
=
−7.4,
d
1.6;
intention-to-treat
(n=299):
−5.4,
1.1)
that
statistically
superior
control,
non-inferior
human-delivered
care,
sustained
By
combining
AI
support,
achieved
outcomes
comparable
care
while
significantly
reducing
required
clinician
time.
These
findings
highlight
immense
potential
technology
scale
effective
healthcare,
address
unmet
need,
ultimately
impact
quality
life
economic
burden
globally.
International Journal of Law and Psychiatry,
Journal Year:
2024,
Volume and Issue:
94, P. 101984 - 101984
Published: March 23, 2024
Throughout
human
history,
all
new
technology
has
been
met
with
surprise,
anxiety,
panic,
and
-
eventually
prudent
adoption
of
certain
aspects
specific
technological
advances.
This
pattern
is
evident
in
the
histories
most
technologies,
ranging
from
steam
power
nineteenth
century,
to
television
twentieth
now
'artificial
intelligence'
(AI)
twenty-first
century.
Each
generation
believes
that
advances
its
era
are
quantitatively
qualitatively
different
those
previous
generations,
but
underlying
phenomenon
same:
shock
new,
followed
by
more
gradual
adjustment
(and
of)
technology.
These
concerns
apparent
today
relation
AI,
which
reflects
interesting
incremental
on
existing
rather
than
stand-alone
developments.
The
usual
technologies
(e.g.,
they
will
replace
function)
are,
perhaps,
concerning
fields
such
as
mental
capacity
law,
often
applies
people
impaired
decision-making
who
might
be
especially
vulnerable
appear
capable
encroaching
disproportionately
or
other
areas
core
function.
paper
approaches
this
topic
an
historical
standpoint,
noting
both
panics
past
possibilities
offered
AI
today,
provided
it
approached
a
proportionate,
prudent,
person-centered
way,
underpinned
appropriate
ethical
guidance
active
awareness
clinical
legal
practice.
UNSTRUCTURED
Mental
health
services
face
a
multitude
of
challenges,
such
as
increasing
demand,
underfunding
and
limited
workforce
capacity.
The
accelerated
digital
transformation
public
is
positioned
by
government,
private
sector
some
academic
researchers
the
solution.
Alongside,
human-centred
design
(HCD)
has
emerged
guiding
paradigm
for
this
to
ensure
user
needs
are
met.
We
define
what
HCD
are,
how
they
implemented
in
UK
policy
context,
their
role
within
evolving
delivery
mental
services.
Our
co-author’s
involvement
these
policies
over
past
five
years
provides
unique
insights
into
decision-making
process
story.
review
promises,
pitfalls
ongoing
challenges
identified
across
multi-disciplinary
literature.
Finally,
we
propose
future
research
questions
options
that
designed
delivered
meet
population.
Background:
Blended
mobile
health
(mHealth)
interventions
–
combining
self-guided
and
human
support
components
could
play
a
major
role
in
preventing
non-communicable
diseases
(NCDs)
common
mental
disorders
(CMDs).
This
protocol
paper
describes
sequential,
multiple
assignment,
randomised
trial
aimed
at
(i)
evaluating
the
effectiveness
cost-effectiveness
of
LvL
UP,
an
mHealth
lifestyle
intervention
for
prevention
NCDs
CMDs,
(ii)
establishing
optimal
blended
approach
UP
that
balances
effective
personalised
with
scalability.Methods:
is
6-month
holistic
targeting
physical
activity,
diet,
emotional
regulation.
In
this
trial,
young
middle-aged
Singaporean
adults
risk
developing
or
CMDs
will
be
randomly
allocated
to
one
two
initial
conditions
(‘LvL
UP’
‘comparison’).
After
4
weeks,
participants
categorised
as
non-responders
from
group
re-randomised
into
second-stage
conditions:
continuing
(LvL
UP)
additional
motivational
interviewing
(MI)
sessions
by
trained
coaches
+
adaptive
MI).
The
primary
outcome
well-being
(via
Warwick-Edinburgh
Mental
Wellbeing
Scale).
Secondary
outcomes
include
anthropometric
measurements,
resting
blood
pressure,
metabolic
profile,
status,
behaviours
(physical
diet),
work
productivity,
healthcare
utilisation.
Outcomes
measured
baseline,
6
months
(post-intervention),
12
(follow-up).Discussion:
addition
proposed
study
design
contribute
increasing
evidence
on
how
introduce
maximise
their
while
remaining
scalable.Trial
registration:
Pilot
was
prospectively
registered
ClinicalTrials.gov
(NCT06360029)
7
April
2024.