Specimen and data sharing to advance research and development on Zika virus

The Lancet Microbe, Journal Year: 2025, Volume and Issue: unknown, P. 101057 - 101057

Published: Feb. 1, 2025

For diseases with epidemic potential, specimen and data sharing is crucial for sustained research development of medical countermeasures such as diagnostics, therapeutics, vaccines. In the case Zika virus, although a global framework to advance highly desirable, challenges related legal, ethical, intellectual property issues persist. Since 2015-16 virus outbreak, regional laboratory networks partnerships have made some progress in among virus-endemic countries. Pragmatic steps securing funds augmenting capacity, building biobanks within public health infrastructures low-income middle-income countries, clearly defining specimens that need be collected, developing standardised protocols, harmonising system interoperability facilitate sharing, mechanisms benefit will pave way timely deployment emergencies.

Language: Английский

Federated systems for automated infection surveillance: a perspective

Antimicrobial Resistance and Infection Control, Journal Year: 2024, Volume and Issue: 13(1)

Published: Sept. 27, 2024

Automation of surveillance infectious diseases-where algorithms are applied to routine care data replace manual decisions-likely reduces workload and improves quality surveillance. However, various barriers limit large-scale implementation automated (AS). Current strategies for AS in networks include central (i.e. collecting all centrally, algorithm application case ascertainment) or local sharing results with the network coordinating center). In this perspective, we explore whether current challenges can be solved by federated AS. AS, scripts analyses developed centrally locally. We focus on potential context healthcare associated infections (AS-HAI) severe acute respiratory illness (AS-SARI). AS-HAI AS-SARI have common specific requirements, but both would benefit from decreased burden, alignment increased oversight, improved access while preserving privacy. Federated combines some benefits a implemented system, such as standardization an easily scalable methodology, locally system including (near) real-time flexibility algorithms, meeting different information needs improving sustainability, allowance broader range clinically relevant case-definitions. From global it promote development where is not currently possible foster international collaboration.The necessary transformation source likely will place significant burden facilities. may outweighed benefits: comparability results, reuse multiple purposes. Governance stakeholder agreement address accuracy, accountability, transparency, digital literacy, protection, warrants clear attention create acceptance methodology. conclusion, seems solution AS-SARI. Prerequisites successful validation evaluation requirements participants govern understanding

Language: Английский

Toward Better Semantic Interoperability of Data Element Repositories in Medicine: Analysis Study

JMIR Medical Informatics, Journal Year: 2024, Volume and Issue: 12, P. e60293 - e60293

Published: Sept. 30, 2024

Background Data element repositories facilitate high-quality medical data sharing by standardizing and enhancing semantic interoperability. However, the application of is confined to specific projects institutions. Objective This study aims explore potential issues promote broader within field evaluating analyzing typical repositories. Methods Following inclusion 5 through a literature review, novel analysis framework consisting 7 dimensions 36 secondary indicators was constructed used for evaluation analysis. Results The study’s results delineate unique characteristics different uncover in their construction. These include absence reuse protocols insufficient information regarding scenarios efficacy elements. fully comply with only 45% (9/20) subprinciples Findable Reusable FAIR principle, while achieving 90% (19/20 subprinciples) compliance rate Accessible 67% (10/15 Interoperable. Conclusions recommendations proposed this address improve construction repositories, offering valuable insights managers, computer experts, other pertinent stakeholders.

Language: Английский