Global, regional, and national burden of self-harm among adolescents aged 10-24 years from 1990 to 2021, temporal trends, health inequities and projection to 2041

Frontiers in Psychiatry, Journal Year: 2025, Volume and Issue: 16

Published: March 17, 2025

Self-harm ranks as the third leading cause of disability-adjusted life years (DALYs) among adolescents globally, imposing substantial disease and economic burdens. Comprehensive analyses global temporal trends, health inequities, future projections are crucial for developing effective public policies interventions. This study analyzed global, regional, national age-standardized incidence, mortality, DALYs self-harm using data from Global Burden Disease (GBD) 2021 database. Significant burdens trends were assessed. Projections evaluations employed a combination inequities analysis, age-period-cohort (APC) socio-demographic index (SDI) Joinpoint regression Bayesian APC modeling. The burden demonstrated an overall downward trend. However, in 2021, increased with age is projected to decline further by 2041. analysis revealed generally decreasing trend, although some regions exhibited stable or slightly increasing trends. regional heterogeneities identified. High SDI region showed slight upward trend Southern Latin America experienced largest increase, Middle decrease. Conversely, East Asia most significant reductions both incidence mortality. Age effects pronounced Low-middle regions, while period cohort greater fluctuations regions. Notably, positive, fluctuating nonlinear relationship (r = 0.324, P < 0.001). Gender disparities also significant. Male bore higher whereas female Low disproportionately high incidence. Adolescents aged 15-24 carried greatest burden, females exhibiting males experiencing mortality rates. Despite decline, gender persist. lower particularly vulnerable. These findings underscore need targeted interventions addressing inequalities, optimizing healthcare resource allocation, improving education, reducing socioeconomic costs associated adolescents.

Language: Английский

Randomised clinical trial investigating memory training for recovery-adolescents in addressing psychiatric concerns among adolescents in Iraq

Journal of Global Health, Journal Year: 2025, Volume and Issue: 15

Published: May 4, 2025

In this randomised clinical trial, we investigated the efficacy of MEmory Training for Recovery-Adolescent (METRA) in improving psychiatric symptoms among adolescents Iraq. study, included aged 10-19 years with heightened distress living Kirkuk. It was a parallel-group trial comparing METRA treatment as usual (TAU), three-month follow-up. The study occurred between July 2023 and January 2024. Participants assigned to received 10-session group-intervention comprised memory specificity training writing recovery. Assessments at baseline, post-intervention, three months after treatment. Primary outcome measures were self-reported posttraumatic stress disorder (PTSD) depression post-intervention. Secondary outcomes anxiety difficulties. We also examined costs affordability humanitarian context. sample size primary analyses 67 group 65 TAU. Following intention-to-treat principle, linear mixed effects models found post-intervention had 10.96-point decrease (95% confidence interval (CI) = -13.82, -8.09) PTSD 3.27-point CI -4.67, -1.87) symptoms. Improvements maintained While time main significant (P < 0.001), × interactions not 0.61 P 0.71 depression); thus, there no evidence that these improvements superior symptom observed while more effective than TAU, it less costly, offering an option replacing current practice. findings highlight need further research area global mental health. Australian New Zealand Clinical Trials Registry (ACTRN12622001413718).

Language: Английский