Global, regional, and national burden of self-harm among adolescents aged 10-24 years from 1990 to 2021, temporal trends, health inequities and projection to 2041 DOI Creative Commons

Jiang Tan,

Yanping Shu, Qing Li

et al.

Frontiers in Psychiatry, Journal Year: 2025, Volume and Issue: 16

Published: March 17, 2025

Self-harm ranks as the third leading cause of disability-adjusted life years (DALYs) among adolescents globally, imposing substantial disease and economic burdens. Comprehensive analyses global temporal trends, health inequities, future projections are crucial for developing effective public policies interventions. This study analyzed global, regional, national age-standardized incidence, mortality, DALYs self-harm using data from Global Burden Disease (GBD) 2021 database. Significant burdens trends were assessed. Projections evaluations employed a combination inequities analysis, age-period-cohort (APC) socio-demographic index (SDI) Joinpoint regression Bayesian APC modeling. The burden demonstrated an overall downward trend. However, in 2021, increased with age is projected to decline further by 2041. analysis revealed generally decreasing trend, although some regions exhibited stable or slightly increasing trends. regional heterogeneities identified. High SDI region showed slight upward trend Southern Latin America experienced largest increase, Middle decrease. Conversely, East Asia most significant reductions both incidence mortality. Age effects pronounced Low-middle regions, while period cohort greater fluctuations regions. Notably, positive, fluctuating nonlinear relationship (r = 0.324, P < 0.001). Gender disparities also significant. Male bore higher whereas female Low disproportionately high incidence. Adolescents aged 15-24 carried greatest burden, females exhibiting males experiencing mortality rates. Despite decline, gender persist. lower particularly vulnerable. These findings underscore need targeted interventions addressing inequalities, optimizing healthcare resource allocation, improving education, reducing socioeconomic costs associated adolescents.

Language: Английский

Global, regional, and national burden of self-harm among adolescents aged 10-24 years from 1990 to 2021, temporal trends, health inequities and projection to 2041 DOI Creative Commons

Jiang Tan,

Yanping Shu, Qing Li

et al.

Frontiers in Psychiatry, Journal Year: 2025, Volume and Issue: 16

Published: March 17, 2025

Self-harm ranks as the third leading cause of disability-adjusted life years (DALYs) among adolescents globally, imposing substantial disease and economic burdens. Comprehensive analyses global temporal trends, health inequities, future projections are crucial for developing effective public policies interventions. This study analyzed global, regional, national age-standardized incidence, mortality, DALYs self-harm using data from Global Burden Disease (GBD) 2021 database. Significant burdens trends were assessed. Projections evaluations employed a combination inequities analysis, age-period-cohort (APC) socio-demographic index (SDI) Joinpoint regression Bayesian APC modeling. The burden demonstrated an overall downward trend. However, in 2021, increased with age is projected to decline further by 2041. analysis revealed generally decreasing trend, although some regions exhibited stable or slightly increasing trends. regional heterogeneities identified. High SDI region showed slight upward trend Southern Latin America experienced largest increase, Middle decrease. Conversely, East Asia most significant reductions both incidence mortality. Age effects pronounced Low-middle regions, while period cohort greater fluctuations regions. Notably, positive, fluctuating nonlinear relationship (r = 0.324, P < 0.001). Gender disparities also significant. Male bore higher whereas female Low disproportionately high incidence. Adolescents aged 15-24 carried greatest burden, females exhibiting males experiencing mortality rates. Despite decline, gender persist. lower particularly vulnerable. These findings underscore need targeted interventions addressing inequalities, optimizing healthcare resource allocation, improving education, reducing socioeconomic costs associated adolescents.

Language: Английский

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