Health Benefits of Probiotics and Prebiotics Interaction DOI

Ragala Venkata Nandha,

A. R. Heamchandsaravanan,

Priyadarshene Kamalanathan

et al.

Published: Jan. 1, 2024

Language: Английский

The role and mechanism of gut-lung axis mediated bidirectional communication in the occurrence and development of chronic obstructive pulmonary disease DOI Creative Commons

Xiaofan Song,

Xina Dou,

Jiajing Chang

et al.

Gut Microbes, Journal Year: 2024, Volume and Issue: 16(1)

Published: Oct. 24, 2024

The current studies have shown that the occurrence and development of chronic obstructive pulmonary disease (COPD) are closely related to changes in gut health its microenvironment, even some diseases significant clinical correlation with COPD. dysbiosis microbiota observed COPD patients also suggests a potential bidirectional interaction between lung. Communication lung may occur through circulating inflammatory cells, microbial metabolites, mediators, but mechanism communication is still under study. Therefore, more research needed this area. In review, we summarize recent animal models on role gut-lung axis mechanisms, so as provide ideas for further field. addition, summarized negative effects medication risk factors proposed prevention treatment strategies.

Language: Английский

Citations

4
System Overview from Physiological and Pathological Standpoints DOI
Gustavo Rodrigues Pedrino,

Luíza Toubas Chaul,

Virgínia Farias Alves

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Confrontation of the ambivalent roles of the intestinal microbiota in carcinogenesis: Oncogenic or anticancer agents? DOI
Fatouma Mohamed Abdoul‐Latif, Ayoub Ainane,

Omaima Saoudi

et al.

Journal Of Advanced Pharmacy Education And Research, Journal Year: 2025, Volume and Issue: 15(2), P. 16 - 30

Published: Jan. 1, 2025

Language: Английский

Citations

0
Parabacteroides johnsonii Inhibits the Onset and Progression of Colorectal Cancer by Modulating the Gut Microbiota DOI
Jing Liu, Yong Zhang, Li–Yan Xu

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: April 7, 2025

Abstract Background Colorectal cancer (CRC) is the third most prevalent malignant tumor and second leading cause of cancer-related deaths globally. The genus Parabacteroides an important component gut microbiota. P. distasonis goldsteinii are reported probiotics, their roles in CRC have been investigated related studies. However, association between johnsonii remains unknown. Methods (10–42) Lactococcus formosensis (22–2) were isolated from healthy human feces. 25 mice that demonstrated normal feeding activity randomly assigned to four groups : control (NC group), model (IC (PJ L. (LO group). Colonic tissues IC, PJ, LO colon NC group then collected for HE staining immunohistochemical staining. Fecal samples during hyperproliferative adenoma phases Metagenomic sequencing metabolite analysis. Results intervention reduced number slowed growth colonic tumors, improved histological scores, decreased microenvironmental inflammation levels. composition intestinal flora with cancer, increased microbial species diversity, maintained microbiota stability. Furthermore, abundance Bifidobacterium pseudolongum Lactobacillus, which play a role ameliorating AOM/DSS-induced dysbiosis. affected metabolic pathways, including amino sugar degradation galactose metabolism, sphingolipid synthesis, acid polyphenol synthesis tryptophan metabolism pathway as primary being affected. Conclusion Our study profiled administration reduces tumors lower staging by modulating its metabolites at early stages.

Language: Английский

Citations

0
COVID-19, Long COVID, and Gastrointestinal Neoplasms: Exploring the Impact of Gut Microbiota and Oncogenic Interactions DOI Open Access
Amália Cínthia Meneses do Rêgo, Irami Araújo-Filho

Archives of Cancer Science and Therapy, Journal Year: 2024, Volume and Issue: 8(1), P. 054 - 062

Published: Sept. 4, 2024

Background: The impact of COVID-19 and long-term on gastrointestinal neoplasms remains underexplored. current review investigates the potential link between these conditions role gut microbiota in mediating oncogenic processes. Dysbiosis, characterized by alterations microbial composition, may exacerbate inflammation immune dysregulation, contributing to cancer development. Methods: A comprehensive literature was conducted using databases including PubMed, Scopus, Embase, SciELO, Web Science. Inclusion criteria encompassed studies published 2020 2024 that explored intersection COVID-19, cancers. articles were critically appraised for quality relevance, data synthesized elucidate common mechanisms outcomes. Results: identifies several which influence risk patients. Persistent inflammation, oxidative stress, dysfunction observed Long COVID associated with dysbiosis. Specific metabolites, such as secondary bile short-chain fatty acids, implicated promoting tumorigenesis. Comparative analysis suggests SARS-CoV-2-induced dysbiosis heighten susceptibility cancers, particularly patients prolonged post-infection symptoms. Conclusion: findings underscore need further research clarify development among These could inform preventative strategies therapeutic interventions, those experiencing COVID. highlights gaps knowledge advocates longitudinal assess effects health.

Language: Английский

Citations

0
Health Benefits of Probiotics and Prebiotics Interaction DOI

Ragala Venkata Nandha,

A. R. Heamchandsaravanan,

Priyadarshene Kamalanathan

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

0