The Role of Physical Exercise in Chronic Kidney Disease DOI Creative Commons

Cláudia Antunes,

Daniela Antunes, Ana Ponciano

et al.

Portuguese Journal of Nephrology & Hypertension, Journal Year: 2023, Volume and Issue: 37

Published: June 28, 2023

Chronic kidney disease (CKD) affects more than 10% of the general population worldwide, amounting to 800 million individuals. Some important conditions associated with CKD are hypertension, diabetes, dyslipidemia, sedentary lifestyle, and smoking. According World Health Organization (WHO), regular physical activity helps prevent manage non-communicable diseases such as diabetes weight reduction. It is known that a decrease in systolic blood pressure significant reduction all causes mortality major cardiovascular events. As far concerned, beyond first-line medication, healthy lifestyle behaviours should be considered, which included. Training leads improved skeletal muscle response increased expression proteins involved glucose metabolism insulin sensitivity. Concerning one recommended interventions encompasses noting patients low, moderate, or high risk, depending on LDL value, treatment involves loss its association pharmacotherapy. have some particularities condition exercise prescription interpretation benefits. This review intended systematize importance determinants.

Language: Английский

Consensus Guidance for Monitoring Individuals With Islet Autoantibody–Positive Pre-Stage 3 Type 1 Diabetes DOI Open Access
Moshe Phillip, Peter Achenbach, Ananta Addala

et al.

Diabetes Care, Journal Year: 2024, Volume and Issue: unknown

Published: June 24, 2024

Given the proven benefits of screening to reduce diabetic ketoacidosis (DKA) likelihood at time stage 3 type 1 diabetes diagnosis, and emerging availability therapy delay disease progression, programs are being increasingly emphasized. Once broadly implemented, initiatives will identify significant numbers islet autoantibody-positive (IAb+) children adults who risk for (confirmed single IAb+) or living with (multiple early-stage (stage 2) diabetes. These individuals need monitoring progression; much this care happen in nonspecialized settings. To inform monitoring, JDRF, conjunction international experts societies, developed consensus guidance. Broad advice from guidance includes following: 1) partnerships should be fostered between endocrinologists primary providers people IAb+; when IAb+ initially identified, there is a confirmation using second sample; 3) lower progression than multiple individuals; 4) have periodic medical including regular assessments glucose levels, education about symptoms DKA, psychosocial support; 5) interested 2 offered trial participation approved therapies; 6) all health professionals involved responsibility provide education. The also emphasizes unmet needs further research on increase rigor future recommendations clinical care.

Language: Английский

Citations

21

Asociaciones de la actividad física, la conducta sedentaria y la condición física con la salud glucémica y cardiometabólica en jóvenes con diabetes tipo 1 DOI Creative Commons
Nidia Huerta‐Uribe

Published: Jan. 10, 2025

The main purpose of this doctoral thesis was to determine whether the physical activity (PA), sedentary behavior and fitness were associated with glycemic control cardiovascular risk factors in children adolescents T1D, if these parameters differed from those apparently healthy peers. In order fulfill objective answer a variety questions that arose during execution project, series reviews existing data analyses our own carried out reported. Thus, Diactive-1 Cohort Study gave rise four studies: First study: Youth type 1 diabetes mellitus are more inactive than peers: A systematic review meta-analysis. Aim: To conduct meta-analysis differences PA, behavior, between T1D their Conclusions: Keeping mind heterogeneity studies design, population assessment, findings show seem be less active, sedentary, have lower CRF levels Second Is fear hypoglycemia major barrier an active lifestyle diabetes? Study. evaluate relationship (FoH) PA metrics T1D. Children FoH had similar without fear. Our results therefore suggest may previously believed. Third Association Between Physical Activity, Sedentary Behavior Fitness Glycated Hemoglobin Type Diabetes: Systematic Review Meta-analysis. meta-analyze association A1c Low extensive explain part variance for poor youth Fourth Handgrip strength, cardiometabolic risk, body composition diabetes. explore handgrip Healthy strength provides significant benefits This tool could considered potential clinical value incorporating assessments like tests monitor intervene regarding health.

Language: Английский

Citations

0

Adipocentric Strategy for the Treatment of Type 2 Diabetes Mellitus DOI Open Access
Juan José Gorgojo Martínez

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(3), P. 678 - 678

Published: Jan. 21, 2025

The global prevalence of obesity and type 2 diabetes mellitus (T2D) has risen in parallel over recent decades. Most individuals diagnosed with T2D exhibit adiposopathy-related (ARD), a condition characterized by hyperglycemia accompanied three core features: increased ectopic visceral fat deposition, dysregulated adipokine secretion favoring pro-inflammatory state, insulin resistance. Despite advancements precision medicine, international guidelines for continue to prioritize individualized therapeutic approaches focused on glycemic control complications, many healthcare providers predominantly maintain glucocentric strategy. This review advocates an adipocentric treatment paradigm most T2D, emphasizing the importance prioritizing weight loss reduction as key drivers intensification. By combining lifestyle modifications pharmacological agents that promote loss—including SGLT-2 inhibitors, GLP-1 receptor agonists, or dual GLP-1/GIP agonists—and, when appropriate, metabolic surgery, this approach offers potential disease remission patients shorter duration. For others, it enables superior compared traditional glucose-centered strategies while simultaneously delivering cardiovascular renal benefits. In conclusion, framework ARD, which represents majority cases, effectively integrates cardio-nephrocentric goals. constitutes optimal strategy ARD due its efficacy achieving remission, improving control, addressing obesity-related comorbidities, reducing morbidity mortality.

Language: Английский

Citations

0

Clinical outcomes of a real‐world prospective study using Dexcom ONE continuous glucose monitoring in people with diabetes treated with two or more insulin injections per day DOI Creative Commons
Daisy Elliott,

Chloe Husband,

Heydar Khadem

et al.

Diabetic Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 28, 2025

Abstract Aims This study assessed real‐world glycaemic outcomes associated with the use of Dexcom ONE in adults suboptimally controlled diabetes. Methods In this single‐site prospective study, type 1 (T1D) or 2 diabetes (T2D) taking two more insulin injections per day initiated CGM and attended follow‐up data collection visits after 3 6 months. During participants received usual care. Primary outcome was a change HbA1c at Additional included participant‐reported CGM‐derived time glucose range 3.9–10 mmol/L (TIR), above >10 (TAR), below <3.9 (TBR). Results There were 110 enrolled [T1D ( n = 34): mean age 36.6 years, 55.9% female; T2D 76): 54.9 38.2% female]. Mean significantly decreased from 90 mmol/mol (10.3%) to 79 (9.4%) months (∆‐12 mmol/mol, p < 0.001) T1D users 86 (10.1%) 67 (8.3%) (∆‐18 0.001). Perception health distress improved for both groups. had modest improvement TBR. exhibited clinically meaningful increase TIR (∆ + 9.0%). Conclusion Real‐world significant reductions months, along improvements outcomes. also improved, possibility there being greater than could be captured study. These findings support expanding access real‐time system.

Language: Английский

Citations

0

The Effectiveness of a Primary Care Diabetes Education and Self‐Management Program in Ireland: A 6‐Month Follow‐Up Study DOI Creative Commons
Clodagh Scannell, Terence W O’Neill, Anne Griffin

et al.

Endocrinology Diabetes & Metabolism, Journal Year: 2025, Volume and Issue: 8(2)

Published: Feb. 19, 2025

ABSTRACT Aims Self‐management education is recognised as an essential element of comprehensive diabetes care. This study aims to assess the impact DESMOND (Diabetes Education and Self‐Management for Ongoing Newly Diagnosed) structured self‐management programme administered by a registered dietitian in primary‐care setting on key clinical indicators (HbA1c, weight BMI) participants who returned locally developed 6‐month follow‐up session. Methods A retrospective analysis was conducted attended 6‐h during 2018 Midwest Ireland. Paired sample t‐tests McNemar chi‐square tests were used any differences between baseline 6 months post‐intervention. Results There 66 participants, mean age 63 years. At follow‐up, HbA1c reduced 6.45 mmol/mol (standard deviation (SD): 15.02 mmol/mol, p = 0.006). The number below 53 cut‐off increased from 52% at 71% ( < 0.001). reduction 1.4 kg (SD: 4.4 kg, 0.21) found follow‐up. Those overweight BMI category decreased 30.2% 26.4%, clinically significant result. Conclusion Better glycaemic control improvements seen among program supports emerging evidence effectiveness Further research required determine optimal contact time frequency sessions order sustain observed improvement outcomes.

Language: Английский

Citations

0

Incorporating Complementary Therapies Into Diabetes Care DOI Creative Commons
Julia E. Blanchette,

Forrest Paquin,

B. Dobbs

et al.

The Journal of Clinical Endocrinology & Metabolism, Journal Year: 2025, Volume and Issue: 110(Supplement_2), P. S137 - S146

Published: Feb. 25, 2025

Abstract Context Current diabetes care and education programs expert clinical management guidelines focus on self-care behaviors have yet to incorporate complementary therapies. Complementary therapies, such as music therapy, yoga, mindfulness, art been used globally for centuries positive metabolic glycemic outcomes. In this mini-review, we describe therapies successfully in diabetes, identify current evidence-based practice gaps, provide recommendations incorporating into care. Evidence Acquisition We thoroughly searched relevant PubMed Google Scholar studies from 2004 2024. Our inclusion criteria were trial using the search terms “diabetes self-management” OR “metabolic outcomes” “diabetes” “type of therapy (music yoga or therapy) population (type 1 type 2 prediabetes, diabetes).” Synthesis synthesized evidence determine that benefit individuals with diabetes. Findings showed support diabetes-related psychological cardiometabolic outcomes enhance Association Diabetes Care Education Specialists 7 Self-Care Behaviors self-management, specifically healthy coping, monitoring, reducing risks, problem-solving. Critical gaps included lack large-scale randomized controlled trials North American self-management programs. Conclusion physiological health benefits people living more are needed assess their effectiveness a large scale. interim, can be integrated education, adjunctive hands-on meet goals.

Language: Английский

Citations

0

Comparative Analysis of AI Tools for Disseminating ADA 2025 Diabetes Care Standards: Implications for Cardiovascular Physicians DOI Creative Commons
Tengfei Zheng

Journal of Diabetes, Journal Year: 2025, Volume and Issue: 17(3)

Published: March 1, 2025

Language: Английский

Citations

0

Phenotypic Consensus Clustering and Treatment Heterogeneity Analysis in Critically Ill Patients with Comorbid Type 2 Diabetes Mellitus DOI Creative Commons
Xiujuan Chen, Jiaqi Sun, Huixian Li

et al.

Archives of Medical Research, Journal Year: 2025, Volume and Issue: 56(5), P. 103197 - 103197

Published: March 10, 2025

Language: Английский

Citations

0

Type 2 Diabetes Self-Care in Oxcutzcab, Yucatan, Mexico: The Role of Mental Health DOI

Pardo Aguilar,

Jenifer J. Thomas, Antonio Vicente Yam Sosa

et al.

Journal of Transcultural Nursing, Journal Year: 2025, Volume and Issue: unknown

Published: March 18, 2025

Introduction: Understanding mental health in the context of type 2 diabetes self-care behaviors may lead to improvements disease prognosis, overall well-being, and delivery services. The purpose this study was understand differences adherence treatment among individuals who report anxiety, anger, depression. Methods: Questionnaires were administered 111 with Oxcutzcab, Yucatan, Mexico. Participants completed State-Trait Anxiety Inventory, Anger Expression Inventory-2, Beck Depression Scale Adherence Diabetes Mellitus Type Treatment. Results: Independent-samples t -test used determine mean variables for variables. Overall, reported levels depression differed certain adherence-related experiences. Discussion: Our results indicate importance assessment support as part management process Yucatan.

Language: Английский

Citations

0

Public Health Impact and Environmental Sustainability of Low/No Calorie Sweeteners’ Use as Food and Beverage Reformulation Tools DOI
Vasiliki Pyrogianni

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Abstract Creating healthier food environments has been identified as a key objective to help halt the global rise of obesity and related chronic diseases. One strategy achieve this goal is reformulate beverage products improve their nutritional profile. Low/no-calorie sweeteners (LNCS) have long used dietary tool for sugar reduction in formulations because ability provide sweet taste with substantial reductions sugars calories. However, despite authorisation use additives following stringent safety assessments ongoing re-evaluations by authorities, concerns about health effects remain. Their benefits weight glucose management also questioned due discrepancies literature resulting from mismatch between evidence randomised controlled trials, which consistent support LNCS substitution sugars, observational studies that report mixed results. At same time, there increased interest environmental impact replacing sweeteners. This case study discusses how using might affect both sustainability providing an overview available on safety, effects, benefits, LNCS. Information © The Author 2025

Language: Английский

Citations

0