Impact of COVID-19 Disease on the Development of Osteomyelitis of Jaws: A Systematic Review

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(15), P. 4290 - 4290

Published: July 23, 2024

Background/Objectives: Osteomyelitis is characterized by an inflammatory process affecting both bone and marrow, leading to cell death the formation of sequestrum. Recent literature from past five years has documented instances osteomyelitis following infections SARS-CoV-2. This systematic review explores link between jaw (OMJ) COVID-19 infections. Methods: adhered PRISMA guidelines, systematically analyzing 2020 2024 sourced databases including Medline, Embase, Scopus, Web Science. PROSPERO ID: CRD42024526257. Results: The selected 42 articles, detailing 201 cases related (COMJ). demographic breakdown included 195 male (74.4%) 67 female patients (25.6%), with a median age 52.7 years, ranging 24 71 years. A significant portion COMJ (41.5%) were hospitalized due COVID-19, 58.5% received corticosteroid therapy. Diabetes mellitus was common comorbidity among (65.1%). Most involved maxilla (182 cases; 90.5%), nearly half showing sinus involvement (49.4%). mandible affected in 19 (9.5%). Mucormycosis aspergillosis emerged as predominant fungal infections, identified 103 (51.2%) 50 (24.9%) cases, respectively. Conclusions: Individuals pre-existing health conditions such diabetes who have been treated for are at increased risk developing OMJ, particularly maxillary osteomyelitis. poses diagnostic therapeutic challenge dental maxillofacial professionals, often first encounter these cases.

Language: Английский

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Severe acute respiratory syndrome coronavirus 2 pathology and cell tropism in tongue tissues of COVID-19 autopsies

Frontiers in Cellular and Infection Microbiology, Journal Year: 2024, Volume and Issue: 14

Published: June 21, 2024

Since 2019, Coronavirus Disease 2019(COVID-19) has affected millions of people worldwide. Except for acute respiratory distress syndrome, dysgeusis is also a common symptom COVID-19 that burdens patients weeks or permanently. However, the mechanisms underlying taste dysfunctions remain unclear. Here, we performed complete autopsies five who died COVID-19. Integrated tongue samples, including numerous buds, salivary glands, vessels, and nerves were collected to map pathology, distribution, cell tropism, receptor distribution severe syndrome coronavirus 2 (SARS-CoV-2) in tongue. Our results revealed all had moderate lymphocyte infiltration around glands lamina propria adjacent mucosa, pyknosis epithelia buds glands. This may be because serous acini, gland ducts, are primary sites SARS-CoV-2 infection. Multicolor immunofluorescence showed readily infects Keratin (KRT)

Language: Английский

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Oral pressure injuries in patients hospitalized during the COVID-19 pandemic and associated factors: a cross-sectional study

Concilium, Journal Year: 2024, Volume and Issue: 24(4), P. 1 - 14

Published: Feb. 26, 2024

Background: Patients critically ill with coronavirus disease (COVID) who are admitted to intensive care unit (ICU) susceptible a vast number of complications that life-threatening. Objective: To investigate the frequency oral cavity pressure injuries (OPI) in adult patients hospitalized for COVID an ICU and associated factors. Method: A retrospective cross-sectional study was carried out using electronic medical records ICU, whether due or other conditions (NO COVID), São Luís, Maranhão, Brazil. Demographic data, comorbidities, length stay, intubation time, O2 saturation, use vasoactive drugs, hospitalization (due NO OPI were extracted from records. The data subjected descriptive statistics, Chi-square test, Mann-Whitney test Poisson regression (α=5%). Results: 38.5%. most frequent comorbidities both groups hypertension diabetes mellitus. drugs more group (p=0.010; p=0.021). average stay significantly longer (15.8 days) compared (10.6 (p=0.025). higher (p=0.003; p<0.001). In adjusted analysis, factor suggestive explaining (PR=2.547; CI=1.423-4.558). Conclusion: Longer times responsible cavity, demonstrating need continuous assessment order prevent establishment these injuries.

Language: Английский

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Painful ulcerations associated with COVID-19 in an adolescent patient: a case report

Frontiers in Dental Medicine, Journal Year: 2024, Volume and Issue: 5

Published: Aug. 2, 2024

Oral lesions associated with SARS-CoV-2 (COVID-19) include aphthous-like ulcers, herpetiform eruption of vesicles and erosions other findings. Reactive infectious mucocutaneous (RIME) has recently been used to describe non- Mycoplasma pneumoniae pathogens that can lead rash mucositis. RIME secondary infection is consistent reports in the literature. The patient this case report significant it involves only oral mucosa, although there are cases reported where mucosal involvement limited one site. degree our was presence an acute COVID-19 without ocular or genital involvement. vary presentation. This paper adds understanding systemic manifestations provides a reference clinical findings, management, interdisciplinary collaboration for caring patient.

Language: Английский

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Characteristics of Oral Adverse Effects following COVID-19 Vaccination and Similarities with Oral Symptoms in COVID-19 Patients: Taste and Saliva Secretory Disorders

Medical Principles and Practice, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 33

Published: Dec. 19, 2024

Although COVID-19 vaccines exhibit diverse side effects, taste and saliva secretory disorders have remained poorly understood despite their negative impact on the overall quality of life. The present study aimed to characterize oral adverse effects following vaccination assess similarities with symptoms in patients. A literature search was conducted databases, including PubMed, LitCovid, Google Scholar, retrieve relevant studies. narrative review indicated that a certain number vaccinated people develop ageusia, dysgeusia, hypogeusia, xerostomia, dry mouth, while they are rare compared symptoms. prevalence varies by country/region such geographical differences may be related type vaccine used. Similar SARS-CoV-2 infection, adversely affects perception salivary secretion females older subjects more frequently than males younger subjects. Their impairments mostly appear withing three days after vaccination, bitter is specifically impaired some cases. Considering share characteristics patients, it speculated spike protein derived from infection pathophysiologically responsible for disorders. This because has potential interact ACE2 expressed cells, produce proinflammatory cytokines, form antiphospholipid antibodies. Our results do not deny advantage but attention should paid post-vaccination addition

Language: Английский

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Comparison of Oral Manifestations in Hospitalized COVID-19 Positive Patients and COVID-19 Negative Dental Outpatients. A Case Series Study and Literature Review

International Journal of Otolaryngology and Head &amp Neck Surgery, Journal Year: 2024, Volume and Issue: 13(03), P. 225 - 250

Published: Jan. 1, 2024

Language: Английский

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