The Interplay of Selenium and Human Health DOI
Samy G. Alamir, Ahmed Al‐Harrasi, Adel Ehab Ibrahim

et al.

IntechOpen eBooks, Journal Year: 2025, Volume and Issue: unknown

Published: April 23, 2025

This chapter delves into the intriguing dual nature of selenium (Se), a vital yet paradoxical essential trace element for human health. While indispensable numerous physiological processes, Se has an extremely narrow margin between its benefits and potential toxicity, making intake delicate balancing act. Still, consumption varies globally due to dietary habits, geographic differences, environmental conditions. Se’s history, sources, biomarkers, nutritional guidelines, deficiency toxicity implications are discussed. It also provides in-depth look at pivotal role selenoproteins, including their synthesis, various types, functions, concerns arising from or genetic variations. From supporting brain, fertility, development, immunity regulating thyroid function, these proteins illustrate multifaceted importance in biology. Notably, emerged as contaminant that warrants attention. To address this challenge, contamination remediation strategies, analysis methods were summarized.

Language: Английский

Interactive effect between Selenium and Vitamin C levels on risk of hypertension among adult women in the United States: evidence from NHANES 2011 to 2020 DOI Creative Commons
Dong-Fang Wu, Ping Fan,

Sze Wan Ching

et al.

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: March 13, 2025

Background Hypertension poses an imperative global health risk, affecting over 1 billion people and contributing to cardiovascular disease, especially for women. While previous studies suggest micronutrients such as Vitamin C or Selenium can help reduce blood pressure, research on their interactive effects remains limited. Methods This cross-sectional study analyzed data from 9,343 women aged 20 years older in NHANES (2011–2020). Logistic regression analysis was conducted evaluate the effect of each micronutrient hypertension. To account potential interactions between micronutrients, we calculated relative excess risk due interaction, which assessed combined Results We confirmed individual associations with hypertension, showing significant negative correlations ( p < 0.05). Participants were then divided into four groups, those high intakes both had a significantly lower hypertension 0.05), supporting association intake these nutrients though no synergistic observed. Conclusion The findings support prevention, broadening thoughts level nutrition treatment These results adequate supplementation pressure. However, further rigorous clinical are essential validate strengthen findings.

Language: Английский

Citations

0
The Interplay of Selenium and Human Health DOI
Samy G. Alamir, Ahmed Al‐Harrasi, Adel Ehab Ibrahim

et al.

IntechOpen eBooks, Journal Year: 2025, Volume and Issue: unknown

Published: April 23, 2025

This chapter delves into the intriguing dual nature of selenium (Se), a vital yet paradoxical essential trace element for human health. While indispensable numerous physiological processes, Se has an extremely narrow margin between its benefits and potential toxicity, making intake delicate balancing act. Still, consumption varies globally due to dietary habits, geographic differences, environmental conditions. Se’s history, sources, biomarkers, nutritional guidelines, deficiency toxicity implications are discussed. It also provides in-depth look at pivotal role selenoproteins, including their synthesis, various types, functions, concerns arising from or genetic variations. From supporting brain, fertility, development, immunity regulating thyroid function, these proteins illustrate multifaceted importance in biology. Notably, emerged as contaminant that warrants attention. To address this challenge, contamination remediation strategies, analysis methods were summarized.

Language: Английский

Citations

0