
Journal of Education and Health Promotion, Journal Year: 2025, Volume and Issue: 14(1)
Published: March 1, 2025
BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has resulted in high mortality among hospitalized patients; thus, identifying markers treating these patients is essential. To evaluate the association between viral load and serum biomarkers with COVID-19. MATERIALS AND METHODS: A retrospective cohort study was conducted 198 inpatient records from a tertiary hospital Mexico City January April 2021. severe acute respiratory syndrome 2 (SARS-CoV-2) death due to COVID-19 assessed using Cox regression models. RESULTS: median age 54.9 years, 61.6% were males. rate 43.4%. After adjusting for potential confounders, higher [adjusted hazard ratio (aHR) = 1.56; 95% confidence interval (95% CI) 1.01, 2.42; P value 0.041]; concentrations of BUN (aHR 4.87;95% CI 2.70, 8.79; 0.001), creatinine 1.60;95% 2.54; 0.043), osmolality 4.37;95% 2.34, 8.14; glucose 2.41;95% 1.40, 4.18; 0.001) more likely have fatal prognosis. Conversely, risk lower lymphocytes 0.47;95% 0.30, 0.72; 0.001). CONCLUSION: SARS-CoV-2 such as BUN, creatinine, glucose, osmolarity, could help physicians identify individuals who require closer monitoring.
Language: Английский