Preliminary Pharmacological Screening of Corchorus olitorius Extracts for Anti-inflammatory and Wound Healing Activity
Pratap Chandra Pradhan,
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Mohan Lal Kori
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International Journal of Pharmaceutical Sciences and Drug Research,
Journal Year:
2023,
Volume and Issue:
unknown, P. 556 - 563
Published: Sept. 30, 2023
Aim
of
present
study
was
to
investigate
the
preliminary
screening
aerial
part
Corchorus
olitorius
extracts
for
anti-inflammatory
and
wound-healing
activity
on
experimental
animals.
Different
with
respective
solvents
i.e.
petroleum
ether,
chloroform,
ethyl
acetate,
ethanol
aqueous
C.
were
obtained
by
successive
solvent
extraction.
All
screened
using
Xylene-induced
ear
edema
in
mice
wound
healing
effect
studied
incision
model
mice.
The
weight
lobes
biochemical
measurements,
nitric
oxide
(NO)
levels
MPO
tissue
sample
used
detect
effect.
observed
measurement
tensile
strength
protein
hydroxyproline
level
assessment
healed
tissues.
Observations
confirmed
that
extract
(EECO)
showed
significant
(p<0.05)
inhibition
NO
decreased
significantly
EECO-treated
Wound
potential
improvement
as
well
In
conclusion,
found
most
effective
through
reduction
Language: Английский
QUALITATIVE AND QUANTITATIVE ANALYSIS OF PHYTOCONSTITUENTS IN THE UNANI FORMULATION HABB-E-BUKHAR
Seema Firdouse,
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Shiny Ahmed,
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MOHAMMED ABDUL MUNAIM
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et al.
International Journal of Current Pharmaceutical Research,
Journal Year:
2024,
Volume and Issue:
unknown, P. 36 - 41
Published: May 15, 2024
Objective:
Habb-e-Bukhar
is
a
specific
medication
regimen
in
the
traditional
unani
system
for
treating
fever
caused
by
conditions
such
as
elephantiasis
and
intestinal
diseases.
It
acts
both
an
Antipyretic
Diaphoretic
to
address
acute
fever.
Methods:
The
current
research
aims
analyze
qualitative
quantitative
composition
of
assess
primary
secondary
metabolites
present
sample
extract.
study
utilized
range
advanced
analytical
methods
FTIR,
AAS,
HPLC,
GC-MS
analysis.
was
prepared
through
maceration
method,
initial
phytochemical
screening
revealed
presence
Alkaloids,
Carbohydrates,
Volatile
oils,
Flavonoids,
Glycosides,
Steroids,
triterpenoids.
Results:
Fourier-transform
infrared
spectroscopy
reveals
identification
functional
groups
at
wavenumbers:
3960.26
Amide,
3687.85
Alcohol,
2765.05
Aliphatic,
2099.54
Alkynes;
well
as,
wavelength
1641.55
denoting
Alkenes
(C=C).
Moreover,
findings
from
Atomic
Absorption
spectrometer
suggest
that
drug
contains
notable
levels
certain
heavy
metals,
chromium
0.00642
ppm,
lead
10.00
argon
three
ppm
detected
with
precision
their
respective
wavelengths.
Conclusion:
technique
detect
characterize
phytochemicals
found
ethanolic
indicated
existence
seven
constituents.
Language: Английский