Applications and retention properties of alternative organic mobile phase modifiers in reversed-phase liquid chromatography DOI Creative Commons
Sanka N. Atapattu

Journal of Chromatography Open, Journal Year: 2024, Volume and Issue: 5, P. 100135 - 100135

Published: May 1, 2024

Reverse-phase liquid chromatography has been a widely used analytical technique in many laboratories around the world for several decades. In reverse-phase method development applications, majority of chemists, use organic phase modifiers is limited to acetonitrile and methanol. an effort minimise impact on environment while improving analyst health safety, seen rise interest greening procedures, including environmentally friendly alternative modifiers. Another focus exploring maximise selectivity space typically octadecylsiloxane-bonded silica stationary phase. The aim this review explore how chemists employed solvents as various applications their retention properties.

Language: Английский

Applications and retention properties of alternative organic mobile phase modifiers in reversed-phase liquid chromatography DOI Creative Commons
Sanka N. Atapattu

Journal of Chromatography Open, Journal Year: 2024, Volume and Issue: 5, P. 100135 - 100135

Published: May 1, 2024

Reverse-phase liquid chromatography has been a widely used analytical technique in many laboratories around the world for several decades. In reverse-phase method development applications, majority of chemists, use organic phase modifiers is limited to acetonitrile and methanol. an effort minimise impact on environment while improving analyst health safety, seen rise interest greening procedures, including environmentally friendly alternative modifiers. Another focus exploring maximise selectivity space typically octadecylsiloxane-bonded silica stationary phase. The aim this review explore how chemists employed solvents as various applications their retention properties.

Language: Английский

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