Advancements in Autophagy Modulation for the Management of Oral Disease: A Focus on Drug Targets and Therapeutics

Biomedicines, Journal Year: 2024, Volume and Issue: 12(11), P. 2645 - 2645

Published: Nov. 19, 2024

Autophagy is an intrinsic breakdown system that recycles organelles and macromolecules, which influences metabolic pathways, differentiation, thereby cell survival. Oral health essential component of integrated well-being, it critical for developing therapeutic interventions to understand the molecular mechanisms underlying maintenance oral homeostasis. However, because complex dynamic relationship between autophagy health, associated treatment modalities have not yet been well elucidated. Determining how affects at level may enhance understanding prevention targeted diseases. At level, hard soft tissues develop interactions epithelial mesenchymal cells. Aging contributes progression various disorders including periodontitis, cancer, periapical lesions during aging. levels decrease with age, thus indicating a possible association In this review, we critically review aspects their significance in context diseases lesions, periodontal conditions, candidiasis. A better its can guide us new preventative strategies management

Language: Английский

The enigma of mitochondrial epigenetic alterations in air pollution-induced neurodegenerative diseases

NeuroToxicology, Journal Year: 2024, Volume and Issue: 105, P. 158 - 183

Published: Oct. 5, 2024

Language: Английский

Air Pollution-Linked Epigenetic Modifications in Placental DNA: Prognostic Potential for Identifying Future Foetal Anomalies

Reproductive Toxicology, Journal Year: 2024, Volume and Issue: 129, P. 108675 - 108675

Published: July 27, 2024

Language: Английский