Ruthenium catalyst with a planar-chiral arene ligand: synthesis, separation of enantiomers, and application in C-H activation of N-methoxy-benzamides DOI Creative Commons
Mikhail A. Boym, Roman A. Pototskiy, Evgeniya Podyacheva

et al.

Published: Jan. 11, 2024

Heating tert-butyl-tetraline with [(p-cymene)RuCl2]2 produces the racemic complex [(arene)RuCl2]2, which can be separated into enantiomers by chromatography of its diastereomeric adducts chiral phosphine ligand. The resolved catalyzes C-H activation N-methoxy-benzamides and their annulation N-vinyl-pivaloyl amide giving dihydroisoquinolones in 50-90% yields 70:30-90:10 enantiomeric ratio.

Language: Английский

Ruthenium catalyst with a planar-chiral arene ligand: synthesis, separation of enantiomers, and application in C-H activation of N-methoxy-benzamides DOI Creative Commons
Mikhail A. Boym, Roman A. Pototskiy, Evgeniya Podyacheva

et al.

Published: Jan. 11, 2024

Heating tert-butyl-tetraline with [(p-cymene)RuCl2]2 produces the racemic complex [(arene)RuCl2]2, which can be separated into enantiomers by chromatography of its diastereomeric adducts chiral phosphine ligand. The resolved catalyzes C-H activation N-methoxy-benzamides and their annulation N-vinyl-pivaloyl amide giving dihydroisoquinolones in 50-90% yields 70:30-90:10 enantiomeric ratio.

Language: Английский

Citations

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