Ni-catalysed acceptorless dehydrogenative aromatisation of cyclohexanone derivatives enabled by concerted catalysis specific to supported nanoparticles

Published: Feb. 19, 2024

The dehydrogenative aromatisation of cyclohexanone derivatives has had a transformative influence on the synthesis aromatic compounds because functional groups can be easily introduced at desired positions via classic organic reactions without being limited by ortho-, meta- or para-orientations. However, research is still acceptorless aromatisation, especially with regard to nonprecious-metal catalysts. Ni promising candidate catalyst as congener Pd, but thermally Ni-catalysed not been reported even in an oxidative manner difficulty β-hydride elimination and fast re-insertion Ni–H species. Here, we report CeO2-supported Ni(0) nanoparticle for derivatives. This widely applicable various such cyclohexanols, cyclohexylamines, N-heterocycles, enamines N-alkyl piperidones. Through experiments, demonstrate that present reaction was achieved concerted catalysis utilizing metal ensembles unique supported

Language: Английский

Strategies for synthesizing meta-substituted phenols and phenyl ethers: overcoming the ortho-para positioning challenge in benzene rings

New Journal of Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Recent research progress concerning the synthetic methods of meta -substituted phenols and phenyl ethers is reviewed, as well associated reaction mechanisms applications in drug preparation.

Language: Английский