Effectiveness of the dual wavelength diode laser as an adjunct to non-surgical treatment in treating periodontal pocket in periodontitis patients: A randomized clinical study

Lasers in Medical Science, Journal Year: 2025, Volume and Issue: 40(1)

Published: Feb. 10, 2025

Language: Английский

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A drop-like Optical Fiber Salivary pH Sensor: A Rapid and Real-time Detection of Periodontal Disease

Analytical Biochemistry, Journal Year: 2025, Volume and Issue: 701, P. 115818 - 115818

Published: Feb. 20, 2025

Language: Английский

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Increased bacterial load of Filifactor alocis in deep periodontal pockets discriminate between periodontitis stage 3 and 4

Frontiers in Oral Health, Journal Year: 2025, Volume and Issue: 6

Published: March 27, 2025

Introduction Increasing evidence supports the association of Filifactor alocis with periodontitis; therefore, this work was conducted to assess prevalence and proportion F. in subgingival biofilm samples from patients periodontitis stage 3 4, its potential differentiate between these stages. Methods This cross-sectional study included 50 whom were collected using paper points. followed by recording clinical periodontal parameters including plaque index, bleeding on probing, probing pocket depth (PPD), attachment loss (CAL). The total loads bacteria determined via quantitative PCR. Results All diagnosed 3/4 grade B/C, a 727 pockets, which pooled ( n = 114) for microbiological analysis. Qualitative analyses indicated that bacterial load highest 4 C cases, also increased increasing PPD severity CAL. An ROC analysis both concentration could significantly discriminate periodontitis. regression model suggested one-unit increase PPD, CAL explain 23.9% 14.9% concentration, respectively. Conclusion results demonstrate is severe mainly at sites deep pockets greater loss. Additionally, bacterium possesses diagnostic cases different severities.

Language: Английский

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Microbiological and Salivary Biomarkers Successfully Predict Site-Specific and Whole-Mouth Outcomes of Nonsurgical Periodontal Treatment

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(14), P. 4256 - 4256

Published: July 21, 2024

Background/Objectives: Nonsurgical periodontal treatment (NSPT) is the gold-standard technique for treating periodontitis. However, an individual's susceptibility or inadequate removal of subgingival biofilms could lead to unfavorable responses NSPT. This study aimed assess potential salivary and microbiological biomarkers in predicting site-specific whole-mouth outcomes Methods: A total 68 periodontitis patients exhibiting 1111 pockets 4 6 mm depth completed active phase treatment. Clinical parameters, saliva, biofilm samples were collected from each patient at baseline three months after quantitative PCR assay was used detect presence Fusobaterium nucleatum Porphyromonas gingivalis samples. Salivary including matrix metalloproteinase (MMP)-9, glutathione S-transferase (GST), Annexin-1 assayed both qualitatively (Western blot analysis) quantitively (ELISA). Results: NSPT yielded significant improvements all clinical a reduction bacterial load decreased levels MMP-9 together with increased concentrations GST Annexin-1. The binary logistic regression suggested that overall accuracy P. identification, probing pocket depth, interproximal sites 71.1% successful outcomes. biomarker model 79.4% following Conclusions: At baseline, shallow interdental locations lower abundance predictive favorable response site level. Decreased associated can predict

Language: Английский

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Association of salivary Interleukin-6 levels in smokers with periodontitis

Journal of Baghdad College of Dentistry, Journal Year: 2024, Volume and Issue: 36(4), P. 39 - 49

Published: Dec. 15, 2024

Background: Periodontal disease is caused by a combination of factors, with plaque being the primary causative factor. Although periodontal bacteria play significant contribution in onset periodontitis, sustained inflammatory immune reaction, which mostly directed elevation pro-inflammatory cytokines, component responsible for tissue damage associated periodontitis. Interleukin (IL)-6 pleiotropic cytokine, and it released variety cell types. IL-6 crucial processes that lead to has also been linked migration cells. Smoking key potential factor disorders an increase both severity this studay aims assess association between smoking cigarettes salivary levels patients periodontitis comparison healthy controls. Materials Methods: The sample population consisted seventy-four males, they were separated into four different groups: clinically periodontium non-smoker group (n=12), smoker (n=25) (n=25). All participants' saliva samples taken, then clinical parameters looked at (plaque index, bleeding on probing, probing pocket depth attachment level). Biochemical analysis Enzyme-Linked Immunosorbent Assay (ELISA) was used find out how much saliva. Results: found be greater groups compared control non-smoking groups. Most measures correlated significantly concentration saliva.Conclusion: This research revealed smokers (both without periodontitis) have higher amounts their than nonsmokers periodontitis). shows had boosting effect

Language: Английский

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E-cadherin Single Nucleotide Variants Are Associated with Increasing Susceptibility to Periodontitis

European Journal of Dentistry, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 7, 2024

To investigate the association of

Language: Английский

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