Regulation of colon injury and improvement of exercise performance in exhausted running mice by Lactobacillus pentosus CQZC02 DOI Creative Commons

Limin Cai,

Beibei Wang

Frontiers in Physiology, Journal Year: 2024, Volume and Issue: 15

Published: Sept. 20, 2024

In this study, strenuous forced exercise caused intestinal damage and reduced the capacity of mice. However, antioxidant anti-inflammatory properties Lactobacillus pentosus CQZC02 (LPCQZC02) were found to improve both barrier function in The effectiveness LPCQZC02 was confirmed through various methods, including kit detection, pathological observation, quantitative reverse transcription polymerase chain reaction (qRT-PCR), flora analysis. findings demonstrated that could control colonic index, lessen enlargement by intense exercise, extend running duration Serum levels total superoxide dismutase (T-SOD), glutathione (GSH), interleukin-10 (IL-10) elevated, whereas those malondialdehyde (MDA), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α) reduced. mRNA expression analysis revealed colons mice who remarkably exercised, increase zonula occludens-1 (ZO-1), occludin-1, claudin-1 genes. Additionally, skeletal muscle tissue, it downregulate TNF-α level upregulate copper/zinc (Cu/Zn-SOD) manganese (Mn-SOD) levels. Furthermore, reduce promote beneficial bacteria intestines undergoing exercise. conclusion, emerged as a functional probiotic notable advantage over sulfasalazine, medication for conditions, mitigating oxidative inflammation, repairing damage, enhancing motor subjected

Language: Английский

Comparative analysis of the impact of large yellow croaker roe phospholipids on the gut microbiota community structure in normal-diet mice DOI
Rongbin Zhong,

Xinhong Zheng,

Haoyu Zheng

et al.

Food Science of Animal Products, Journal Year: 2025, Volume and Issue: 3(2), P. 9240114 - 9240114

Published: April 8, 2025

Language: Английский

Citations

0
The structural characteristics, beneficial effects and biological mechanisms of food and medicinal plant polysaccharides on exercise-induced fatigue: A review DOI

Keer Yang,

Yishuo Zhang,

Fuhai FANG

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 144046 - 144046

Published: May 1, 2025

Language: Английский

Citations

0
Regulation of colon injury and improvement of exercise performance in exhausted running mice by Lactobacillus pentosus CQZC02 DOI Creative Commons

Limin Cai,

Beibei Wang

Frontiers in Physiology, Journal Year: 2024, Volume and Issue: 15

Published: Sept. 20, 2024

In this study, strenuous forced exercise caused intestinal damage and reduced the capacity of mice. However, antioxidant anti-inflammatory properties Lactobacillus pentosus CQZC02 (LPCQZC02) were found to improve both barrier function in The effectiveness LPCQZC02 was confirmed through various methods, including kit detection, pathological observation, quantitative reverse transcription polymerase chain reaction (qRT-PCR), flora analysis. findings demonstrated that could control colonic index, lessen enlargement by intense exercise, extend running duration Serum levels total superoxide dismutase (T-SOD), glutathione (GSH), interleukin-10 (IL-10) elevated, whereas those malondialdehyde (MDA), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α) reduced. mRNA expression analysis revealed colons mice who remarkably exercised, increase zonula occludens-1 (ZO-1), occludin-1, claudin-1 genes. Additionally, skeletal muscle tissue, it downregulate TNF-α level upregulate copper/zinc (Cu/Zn-SOD) manganese (Mn-SOD) levels. Furthermore, reduce promote beneficial bacteria intestines undergoing exercise. conclusion, emerged as a functional probiotic notable advantage over sulfasalazine, medication for conditions, mitigating oxidative inflammation, repairing damage, enhancing motor subjected

Language: Английский

Citations

0